Anti-necroptotic effects of human Wharton's jelly-derived mesenchymal stem cells in skeletal muscle cell death model via secretion of GRO-α [0.03%]
人脐带华通胶间充质干细胞通过分泌GRO-α抑制骨骼肌细胞死亡模型中的坏死性凋亡效应
Sang Eon Park,Soo Jin Kwon,Sun Jeong Kim et al.
Sang Eon Park et al.
This demonstrates the anti-necroptotic therapeutic effect of GRO-α in the skeletal muscle cell death model. Furthermore, GRO-α also exhibited the anti-necroptotic effect in a Duchenne muscular dystrophy (DMD) mouse model.
The Role of Long Noncoding RNAs in Vascular Smooth Muscle Cell Phenotype and the Pathogenesis of Cardiovascular and Cerebrovascular Aneurysms [0.03%]
长非编码RNA在血管平滑肌细胞表型及心血管和脑血管瘤发病机制中的作用
Hao-Wei Deng,Zi-Ming Ye,Rui-Ting Hu et al.
Hao-Wei Deng et al.
The pathophysiology of aneurysms is complex and diverse, often associated with progressive vessel wall dysfunction resulting from vascular smooth muscle cell death and abnormal extracellular matrix synthesis and degradation.
Mode of cell death in the penile cavernous tissue of type 1 diabetes mellitus rats [0.03%]
糖尿病1型大鼠阴茎海绵体组织的细胞死亡方式研究
Jing Li,Qilan Jiang,Jun Jiang et al.
Jing Li et al.
Background: Diabetes mellitus commonly causes endothelial cell and smooth muscle cell death in penile cavernous tissue....Endothelial cell and smooth muscle cell death are not consistent at different stages of diabetes progression.
Zheng Yin,Jishou Zhang,Zican Shen et al.
Zheng Yin et al.
Regulated cell death (RCD) is a complex process that involves several cell types and plays a crucial role in vascular diseases. Vascular smooth muscle cells (VSMCs) are the predominant elements of the medial layer of blood vessels, and thei...
A Comprehensive Retrospective Study on the Mechanisms of Cyclic Mechanical Stretch-Induced Vascular Smooth Muscle Cell Death Underlying Aortic Dissection and Potential Therapeutics for Preventing Acute Aortic Aneurysm and Associated Ruptures [0.03%]
周期性机械牵张诱导主动脉夹层血管平滑肌细胞死亡的机制及预防急性主动脉瘤和相关破裂的潜在治疗的全面回顾研究
Jing Zhao,Masanori Yoshizumi
Jing Zhao
Acute aortic dissection (AAD) and associated ruptures are the leading causes of death in cardiovascular diseases (CVDs). Hypertension is a prime risk factor for AAD. However, the molecular mechanisms underlying AAD remain poorly understood....
Significantly Improved Cold Preservation of Rat Hind Limb Vascularized Composite Allografts Using the New PrC-210 Free Radical Scavenger [0.03%]
使用新的PrC-210自由基清除剂显著改善大鼠后肢复合组织移植的冷保存效果
William E Fahl,Zeeda H Nkana,Maya M Gitter et al.
William E Fahl et al.
A single 15 s perfusion of PrC-210-containing UW Solution conferred a dose-dependent reduction in CI-induced muscle cell death over 48 h.
ACETYL-COA PRODUCTION BY OCTANOIC ACID ALLEVIATES ACUTE COMPARTMENT SYNDROME-INDUCED SKELETAL MUSCLE INJURY THROUGH REGULATING MITOPHAGY [0.03%]
辛酸通过调节线粒体自噬减轻急性肌间隔综合征引起的骨骼肌损伤
Xiangkang Jiang,Shaoyun Liu,Jingyuan Yang et al.
Xiangkang Jiang et al.
Moreover, NaO treatment enhanced muscle blood perfusion, leading to the inhibition of apoptosis-related skeletal muscle cell death after ACS. In addition, NaO demonstrated the ability to halt skeletal muscle fibrosis and enhance the functional recovery of muscle post-ACS.
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm [0.03%]
血管紧张素1-7通过抑制平滑肌细胞凋亡保护腹主动脉瘤
Anshul S Jadli,Karina P Gomes,Noura N Ballasy et al.
Anshul S Jadli et al.
Abdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects of Ang 1-7 in a murine model of AAA and to investigate...
Differential Effects of High Fat Diets on Resilience to H2O2-Induced Cell Death in Mouse Cerebral Arteries: Role for Processed Carbohydrates [0.03%]
高脂饮食对小鼠脑动脉过氧化氢诱导的细胞死亡抗性的不同影响：加工碳水化合物的作用
Charles E Norton,Rebecca L Shaw,Steven S Segal
Charles E Norton
Inhibiting Src kinases reduced smooth muscle cell death along with [Ca2+]i response to H2O2 only in PCAs from CD mice and eliminated differences between diets. However, Src kinase inhibition did not alter endothelial cell death.
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