Characterization of prion strains and peripheral prion infectivity patterns in E200K genetic CJD patients [0.03%]
E200K基因遗传性克雅氏病患者的朊毒体菌株表征和外周组织朊病毒感染模式
Tomás Barrio,Jean-Yves Douet,Dana Žáková et al.
Tomás Barrio et al.
In this study, we characterized the prion strains responsible for E200K gCJD cases from Slovakia (n = 12), Spain (n = 9), and France (n = 3) using transgenic mouse models expressing human prion protein (PrP).
Li Jia,Lijuan Zhang,Dongjie Wang et al.
Li Jia et al.
Additionally, in vivo xenograft and metastatic mouse models were established. FISH was used to detect circRAPGEF5 expression in LUAD tissues. circRAPGEF5 knockdown inhibited LUAD cell proliferation, migration, and invasion as well as tumor growth and metastasis in vivo.
Structure Elucidation for MALDI Mass Spectrometry Imaging Using Infrared Ion Spectroscopy [0.03%]
基于红外离子谱学的基质辅助激光解析电离质谱成像结构阐明研究
Jelle L Schuurman,Lara van Tetering,Kas J Houthuijs et al.
Jelle L Schuurman et al.
We applied this technique alongside MALDI mass spectrometry imaging to analyse brain tissue from two knockout mouse models of l-lysine catabolism disorders: pyridoxine-dependent epilepsy (ALDH7A1) and glutaric aciduria type 1 (GCDH).
Bile acid accumulation induced by miR-122 deficiency in liver parenchyma promotes cancer cell growth in hepatocellular carcinoma [0.03%]
肝细胞癌中miR-122缺乏引起的肝实质胆汁酸堆积促进癌细胞生长
Jia-Hui Huang,Yi-Hang Li,Juan-Zhen Hong et al.
Jia-Hui Huang et al.
In vivo mouse models showed that miR-122 deficiency of liver parenchymal cells (hepatocytes) in paracancerous tissues resulted in significantly increased BA levels and altered hepatic BA spectrum, thus promoting liver tumor burden, which could be abated by administration of BA sequestrant.
Oxaliplatin-induced neuropathic pain in cancer: animal models and related research progress [0.03%]
奥沙利铂诱导的癌症神经病理性疼痛的动物模型及相关研究进展
Yuxin Jiang,Jie Shi,Wenping Wang et al.
Yuxin Jiang et al.
This review consolidates recent advancements in rat and mouse models of oxaliplatin-induced CINP, with the aim of enhancing modeling success rates and developing models that more accurately mirror disease progression.
Ovarian ROS-dependent IgG accumulation precedes lipofuscin deposition and follicular decline: comparative insights from the bitch and mouse models of ovarian aging [0.03%]
卵巢ROS依赖性IgG积累早于脂褐质沉积和卵泡衰退：来自母犬和小鼠模型的比较见解
Luís Montenegro,Natália Rigos,Catarina Brandão et al.
Luís Montenegro et al.
Introduction: In the ovaries, inflammation, oxidative stress, fibrosis and a unique population of multinucleated giant cells have been linked to aging. However, the role of IgG deposition is unknown. Using the dog to stud...
A refined comparative mouse model of acute and chronic atopic dermatitis [0.03%]
一种精细的老鼠急性期和慢性期特应性皮炎的比较模型
Jinok Kwak,Hyunok Doo,Eun Sol Kim et al.
Jinok Kwak et al.
Although both mouse models showed comparable symptoms and immunological responses, the model induced by the combination of DNCB and OVA more accurately represented canine and human AD compared to the model induced by DNCB alone.
Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells [0.03%]
侧重于成人齿状回神经干细胞的海马体新生神经元转录组分析调查
Laura Micheli,Maurizia Caruso,Giorgio D&#x;Andrea et al.
Laura Micheli et al.
This review is focused on transcriptomic studies that have faced these and other NSC issues by analyzing developmental trajectories of neural cells and NSCs gene expression profiles in specific experimental settings of hippocampal neurogenesis, and also in mouse models with deletion or overexpression
Network Pharmacology and Experimental Validation Reveal Mechanisms of Ilicis Cornutae Folium Water Extract in Treating Hyperuricemia [0.03%]
网络药理学与实验验证揭示了石韦水提物治疗高尿酸血症的机制
Xiaoqi Zhou,Nan Shi,Meihong Ding et al.
Xiaoqi Zhou et al.
Materials and methods: We established hyperuricemic mouse models using an adenine/potassium oxonate combination to evaluate ICFWE's therapeutic effects.
Narirutin downregulates USP15 to inhibit the NLRP3 ubiquitination in HDM-induced allergic rhinitis [0.03%]
narirutin通过下调USP15抑制HDM诱导的过敏性鼻炎中NLRP3泛素化
Jianing Yang,Longzhu Dai,Jingmei Chai et al.
Jianing Yang et al.
In vivo experiments, the AR mouse models were constructed using HDM induction, the nose touching and sneezing of AR mice were recorded.
耗时 0.26466 秒，为您在
48229835
条记录里面共找到 10000 篇文章 [XML]