Lipoplex-based RNA delivery system enhances RNAi efficiency for targeted Pest control in Spodoptera litura [0.03%]
基于lipoplex的RNA传递系统增强RNAi效率以实现对Spodoptera litura的目标防治
Yun-Heng Lu,Yun Liu,Yu-Chun Lin et al.
Yun-Heng Lu et al.
Our findings underscore the promise of Lipoplex nanoparticles as a robust nanocarrier system for RNAi-based pest control, offering both protection and efficient intracellular delivery of RNA molecules in target insect species.
Affinity-based controlled release of interleukin-4 from scaffolds via biotin-streptavidin interactions for immunomodulation [0.03%]
一种基于亲和力的控制释放体系：通过生物素-链霉亲和素相互作用使支架材料负载的干扰素-4可控释放用于免疫调控研究
Victoria A Nash,Juan F Cortes-Troncoso,Phoebe E Chua et al.
Victoria A Nash et al.
Although it is known that conjugation of biotin to large biomolecules reduces its binding affinity for avidin and avidin variants, the potential to control the release of biotinylated molecules by leveraging these changes in affinity interactions has not been thoroughly investigated.
USP47 enhances NRP1-mediated angiogenesis to promote gastric cancer progression [0.03%]
USP47通过增强NRP1介导的血管生成促进胃癌进展
Wei Chen,Huizhi Wang,Haitao Sun et al.
Wei Chen et al.
The limited prognosis for advanced GC patients underscores the need for new therapeutic strategies targeting key molecules involved in tumor progression.
Activated CD4+ T cells upregulate PD-L1 expression on B cells through CD40/CD40L signaling and direct contact in systemic lupus erythematosus [0.03%]
系统性红斑狼疮中活化的CD4+T细胞通过CD40/CD40L信号传导和直接接触上调B细胞PD-L1的表达
Siyuan Lai,Ning Li,Songyue Chen et al.
Siyuan Lai et al.
Flow cytometric analysis revealed that PD-L1+ B cells exhibited upregulated surface expression of the co-stimulatory molecules CD80 and CD86, alongside a concomitant downregulation in the expression of the antigen-presenting molecule human leukocyte antigen DR (HLA-DR).
A trypsin inhibitor from Poincianella pyramidalis (Tul) L.P Queiroz seeds exhibits antimicrobial and antibiofilm properties against Candida albicans and Candida tropicalis [0.03%]
一种从拜尔格红胶树种子中获得的胰蛋白酶抑制剂对白色念珠菌和热带念珠菌具有抗菌和抗生物被膜性能
Ismaell Avelino de Sousa Sobrinho,Claudiane Vilharroel Almeida,Patrícia Gomes et al.
Ismaell Avelino de Sousa Sobrinho et al.
Proteinase inhibitors are molecules with antifungal potential. We described the antifungal and antibiofilm activity, mechanisms of action, and toxicity of the Poincianella pyramidalis tripsin inhibitor (PpyTI), a kunitz inhibitor.
The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions [0.03%]
星形胶质细胞和神经元的表面共享蛋白质组及它们多细胞相互作用的分子基础
Ling Wu,Vijaya Pandey,Vanessa H Casha et al.
Ling Wu et al.
CS SPAN also included molecules dysregulated in diverse brain disorders.
Chemiluminescent semiconductor polymer nanoparticles for sensitive H2O2 detection based on chemiluminescence resonance energy transfer [0.03%]
基于化学发光共振能量转移的化学发光半导体聚合物纳米粒子H2O2检测体系研究
Ximin Mai,Jiahui Li,Pinyi Ma et al.
Ximin Mai et al.
Through the exploration of covalent linkage and optimal conformation, the distance between donor-acceptor molecules has been considerably shortened, thereby greatly enhancing the efficiency of chemiluminescence resonance energy transfer (CRET).
Lanthanide dopant-driven Bi-O covalency modification for optimizing microenvironment and promoting CO2 electrolysis to formate [0.03%]
通过稀土掺杂调控铋氧共价性以优化二氧化碳电还原制甲酸的微环境
Rongqian Ning,Fei Liu,Shuo Geng et al.
Rongqian Ning et al.
However, achieving excellent CO2RR performance necessitates that the adsorption strength of CO2 molecules and reaction intermediates, as well as interface behaviour of H2O, are precisely regulated.
Oxygen plasma induced MoS2/MoOx heterojunction for high performance SERS application [0.03%]
氧等离子体诱导的MoS2/MoOx异质结用于高性能表面增强拉曼散射应用
Xinru Zheng,Wenxi Wen,Yajian Wu et al.
Xinru Zheng et al.
The SERS performance of the substrate was evaluated by using the Rhodamine 6G (R6G) molecules as Raman reporters.
Regulation of epithelial-mesenchymal plasticity in pancreatic ductal adenocarcinoma: Role of key molecules in tumor differentiation and therapy [0.03%]
胰腺导管腺癌上皮间质转化的调控：肿瘤分化和治疗中关键分子的作用
Qi Ling,Meiching Ong,Björn Konukiewitz et al.
Qi Ling et al.
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers, with most patients diagnosed at advanced stages. Therefore, understanding tumor development and improving treatment strategies is critical. Tumor cell plasticity enab...
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