Microglial Refinement of A-Fiber Projections in the Postnatal Spinal Cord Dorsal Horn Is Required for Normal Maturation of Dynamic Touch [0.03%]
小胶质细胞对产后脊髓背角A纤维投射的精炼是动态触觉正常发育所必需的
Yajing Xu,Stephanie C Koch,Alexander Chamessian et al.
Yajing Xu et al.
Sensory systems are shaped in postnatal life by the refinement of synaptic connectivity. In the dorsal horn of the spinal cord, somatosensory circuits undergo postnatal activity-dependent reorganization, including the refinement of primary ...
Age-related LRRK2 G2019S Mutation Impacts Microglial Dopaminergic Fiber Refinement and Synaptic Pruning Involved in Abnormal Behaviors [0.03%]
年龄相关的LRRK2 G2019S突变影响小胶质细胞多巴胺能纤维精炼和突触修剪，进而参与异常行为产生
Qiuyang Zhang,Xiaojuan Cheng,Wei Wu et al.
Qiuyang Zhang et al.
LRRK2 G2019S mutation-induced aberrant microglial morphogenesis, with more branches and junctions per cell, resulted in excessive microglial refinement of dopaminergic (DAergic) fibers.