Potential of irrigants and medicaments in regenerative endodontics: insights from a systematic review on dentin growth factor release [0.03%]
根管内冲洗剂和药物在再生性根尖手术中的潜能——关于牙髓分化因子释放的系统性回顾分析的新见解
Cynthia Luiza Lopes de Oliveira,Farley Mendes Ferreira,Julia Puppin-Rontani et al.
Cynthia Luiza Lopes de Oliveira et al.
The included studies investigated growth factor release associated with irrigants or intracanal medicaments in human dentin. QUIN tool assessed methodological quality. Of the three-thousand-seven-hundred-and-seventy-four screened, seventeen studies were included in the review.
Evaluation of Antibacterial and Cytotoxic Potency of Polyherbal Gel Formulation Containing Achyranthes Aspera and Trachyspermum Ammi as Intracanal Medicament: An in vitro Study [0.03%]
含阿福TestCategory和山奈 Tribe的多药草凝胶制剂作为根管内药物的抗菌和细胞毒性潜力的体外研究
Ram Surath Kumar,Anil V Ankola,Mahantesh B Nagamoti et al.
Ram Surath Kumar et al.
Background: The overwhelming increase of antibiotic-resistant bacteria, and the adverse reactions of using synthetic drugs such as chlorhexidine (CHX) and calcium hydroxide (Ca(OH2))- based intracanal medicaments have made it mandatory to search for effective substitutes....Purpose: Evaluate the antibacterial potential and cytotoxic effects of novel polyherbal gel containing A.aspera and T.ammi, CHX gel, and Ca(OH2) paste based intracanal medicaments in root canal treatment against Enterococcus faecalis (E.faecalis)....Results: Polyherbal gel containing A.aspera and T.ammi, CHX gel, and Ca(OH2) paste-based intracanal medicaments showed statistically significant antibacterial activity (p
Comparative evaluation of the effectiveness of various intracanal medicaments in eliminating Enterococcus faecalis from simulated internal resorption cavities [0.03%]
评价各种根管内药物消除模拟内部吸收腔肠球菌的效果比较研究
Mehmet Çorak,Arzu Kaya Mumcu,Aysel Gülbandılar
Mehmet Çorak
These findings suggest that incorporating these adjuncts into intracanal medicaments may improve disinfection outcomes, offering potential clinical benefits in managing internal root resorption cases.
Comparative Study
Scientific reports. 2025 Jun 5;15(1):19862. DOI:10.1038/s41598-025-03072-x 2025
Effect of continuous chelation irrigation on transforming growth factor-β1 release: An in vitro assay [0.03%]
连续螯合冲洗对转化生长因子-β1释放的影响：体外试验报告
Sree Varshini Sridhar,Karthick Kumaravadivel,Sankar Vishwanath et al.
Sree Varshini Sridhar et al.
Context: Root canal irrigants and medicaments influence the growth factors released from dentin and create a conducive environment for regeneration....Aim: This study assesses the transforming growth factor-beta 1 (TGF-β1) release after using clodronate and etidronate as continuous chelating agents with two different medicaments calcium hydroxide (CH) and triple antibiotic paste (TAP).
Evaluation of antimicrobial efficacy of sodium dichloroisocyanurate as an intracanal medicament against Enterococcus faecalis and Candida albicans [0.03%]
评价二氯异氰尿酸钠作为根管内杀菌药剂对耐甲氧西林粪肠球菌和白色念珠菌的抗菌效果：体外研究
Sangita Ilango,Anupama Ramachandran,Sadasiva Kadandale et al.
Sangita Ilango et al.
Background: Various formulations of medicaments have been used to eradicate Enterococcus faecalis and Candida albicans in secondary endodontic infection. Sodium dichloroisocyanurate (NaDCC) has proven potency to act against E. faecalis....These medicaments were placed inside the root canal using lentulo spirals, sealed, and incubated under aerobic conditions.
Comparative evaluation of transforming growth factor-beta 1 release from dentin matrix with double antibiotic paste, probiotics, and simvastatin as intracanal medicaments: An in vitro study [0.03%]
不同根管内药物诱导牙本质基质转化生长因子-β1释放的体外研究：双抗生素糊剂、益生菌和辛伐他汀的比较评估
K Hanisha Reddy,G Prasanthi,B Devipriya et al.
K Hanisha Reddy et al.
Samples were maintained at 37°C in 100% relative humidity for 7 days, and then the medicaments were removed with 20 mL of deionized water. TGF-β1 growth factor released was assessed by enzyme-linked immunosorbent assay kit.
Effectiveness of Novel Calcium Hydroxide Nanoparticles in the Different Vehicles against Mixed-species Biofilm: An In Vitro and Ex Vivo Study [0.03%]
新型氢氧化钙纳米颗粒在不同载体中对混合菌种生物膜的疗效：体外和体内的研究
Parinthron Rattanakijkamol,Patarawadee Promta,Phenphichar Wanachantararak et al.
Parinthron Rattanakijkamol et al.
Multispecies biofilms were inoculated in 50 root blocks with different medicaments (each n = 10). The colony-forming unit then assessed the viable cell counts.
Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline-1,2,3-Triazole-Anilines as Potential Antitubercular and Anti-HIV Agents [0.03%]
喹啉-1,2,3-三唑-苯胺类抗结核和抗HIV药物的合成、表征、生物评价及计算机辅助设计研究
Snethemba S Magwaza,Darian Naidu,Oluwatoba E Oyeneyin et al.
Snethemba S Magwaza et al.
Thus, better medicaments are required to manage these diseases. Quinolines have shown great potential due to their broad spectrum of biological activity. Thus, quinoline-1,2,3-triazole-aniline hybrids were synthesised in moderate to good yields.
Antibiotic Paste as an Intracanal Medicament in Infected Primary Teeth: A Systematic Review [0.03%]
抗生素糊剂作为乳牙感染根管内的封药：系统评价
Archita Barve,Laxmi Lakade,Preetam Shah et al.
Archita Barve et al.
Advanced formulations such as triple antibiotic paste (TAP), calcium hydroxide (Ca(OH)₂), clindamycin-modified TAP, and nanoparticle-based medicaments have been studied for microbial reduction and clinical outcomes....Out of 381 studies, 11 studies met the inclusion criteria, which evaluated medicaments such as TAP, Ca(OH)₂, clindamycin-modified TAP, 3C paste, chitosan chlorhexidine (CS-CHX) nanoparticles, and herbal alternatives....This study suggests the potential of tailored intracanal medicaments in pediatric endodontics.
Comparative Evaluation of Clinical and Radiographic Success of Pulpotec, Abscess Remedy, and Triple Antibiotic Paste as a Treatment Option in Necrotic Primary Molars: An In Vivo Study [0.03%]
比较评估Pulpotec、脓肿治疗剂和三抗生素糊剂作为处理坏死乳磨牙的临床和放射图形成功的方法：一项体内研究
Kalisipudi Sandeep,Satyam Martha,Punithvathy Rachuri et al.
Kalisipudi Sandeep et al.
Conclusion: All three medicaments demonstrated effectiveness as alternatives to conventional endodontic treatments for necrotic primary molars. Among them, TAP showed the highest efficacy....Clinical significance: This study supports the adoption of alternative medicaments in pediatric dental practice, potentially leading to improved management strategies for managing abscesses in primary teeth and contributing to better long-term oral health for children.
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