Cláudia Allegrini Kairalla,Milena Rodrigues Muniz,Letícia Oba Sakae et al. Cláudia Allegrini Kairalla et al.

Methods: Sprite Zero Sugar was modified with linear sodium polyphosphate (LPP-10g/L) and sodium trimetaphosphate (TMP-10g/L), individually or combined with calcium lactate pentahydrate (CLP-4.35 g/L).

Yashi Cao,Zhaozeng Chen,Yiming Yin et al. Yashi Cao et al.

In vivo, gilteritinib-treated mice exhibited elevated serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH) levels, alongside histopathological damage, all of which were mitigated in Atg7-deficient mice.

Jian Zhu,Huihui Wang,Yue Guan et al. Jian Zhu et al.

Results: DOX treatment increased creatine kinase isoenzyme-MB, lactate dehydrogenase, and brain natriuretic peptide levels, indicating cardiotoxicity.

Nashwa Cheema,Linh Pham,Alexa Nazarian et al. Nashwa Cheema et al.

In contracting myotubes, 810 nm treatment resulted in a significant ~30% increase in intracellular ATP levels and a 20% ± 12 reduction in lactate secretion into cell culture media. 810 nm treated myotubes also had a smaller change in myotube width during contractions, 5% ± 3, suggesting the myotubes

Zheyi Rong,Jingyi Yan,Junbo Wei Zheyi Rong

The impact of circFOXP1 on inflammation was measured by assessing levels of TNF-α, IL-1β, and IL-6, while the effects of circFOXP1 on oxidative stress were evaluated through measurements of reactive oxygen species (ROS), glutathione (GSH), and lactate dehydrogenase (LDH) levels.

Tie-Ning Zhang,Xin-Mei Huang,Linus Li et al. Tie-Ning Zhang et al.

Background: Serum lactate levels are used to evaluate tissue hypoxia and predict outcomes in cases of sepsis and septic shock. Lactate can participate in a posttranslational modification known as lactylation. Myocardial depression during sepsis and septic shock is common....Here, we investigated the role of lactate in sepsis-induced myocardial depression. Methods: Septic myocardial depression in rats was induced by lipopolysaccharide administration or cecal ligation and puncture....We confirmed that lactylation at these sites was influenced by lactate levels and inhibited the HADHA activity, which disturbed mitochondrial function, ATP production, and energy metabolism. This reduction in the contraction force of cardiomyocytes can influence heart function in vitro and in vivo.

Yuta Kano,Tetsuhito Muranaka,Wataru Saito et al. Yuta Kano et al.

The presence of liver metastasis and elevated lactate dehydrogenase (LDH) levels on pre-treatment blood tests was considered a risk factor for the development of TLS. Therefore, blood tests were performed on day three after the initiation of mFOLFOX6 therapy, which revealed the onset of TLS.

Yiğit Kılıç,Şenay Güven Baysal,Özlem Gül et al. Yiğit Kılıç et al.

There was also a significant negative correlation between cardiopulmonary bypass time, cross-clamping time, mean plasma lactate levels (mmol/L) on postoperative Days 2-5, postoperative creatinine, and motor composite scores.

ZhongLi Hu,Lijia Pei,ZhongTing Hu et al. ZhongLi Hu et al.

When comparing the clinical characteristics of MDS patients, MLR showed a strong correlation with the total white blood cell count at the initial diagnosis (r = 0.661, p = 0.0004), while NLR demonstrated a correlation with lactate dehydrogenase (LDH; r = 0.313, p = 0.037).

Eva Llamas-Amor,Silvia Martínez-Subiela,Fernando Tecles et al. Eva Llamas-Amor et al.

Haptoglobin and lactate dehydrogenase showed significant increases in pigs with PRRSV activation compared to pigs without clinical signs.