主题词1:intestinal+inflammation
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Unraveling the Serum Protein Landscape in Celiac Disease: Current Evidence and Future Directions [0.03%] 解密乳糜泻血清蛋白质谱的现状及未来研究方向
Sajjad Bakhtiari,Behrooz Ahmadi,Nastaran Asri et al. Sajjad Bakhtiari et al.
Background: Celiac disease (CD) is a chronic autoimmune disorder characterized by an abnormal immune response to gluten, leading to intestinal inflammation and various clinical manifestations.
Q33.12024 Review Immunity, inflammation and disease. 2025 May;13(5):e70169. DOI:10.1002/iid3.70169 2025
Moxibustion regulates KDM4D expression and modulates lipid metabolism to inhibit tumor proliferation in CAC mice [0.03%] 温灸通过调控KDM4D表达及脂代谢抑制CAC小鼠肿瘤增殖作用机制研究
Guona Li,Jindan Ma,Luyi Wu et al. Guona Li et al.
Moxibustion, a therapeutic approach in traditional Chinese medicine, can inhibit intestinal inflammation and improve the intestinal mucosa.
Gut Expansion of a Human Lupus Pathobiont is Associated With Autoantibody Production and T Cell Dysregulation [0.03%] 人狼疮病原共生体的肠道扩张与自身抗体产生和T细胞失调有关
Longhuan Ma,Yong Ge,Natalie Six et al. Longhuan Ma et al.
The combination of TC microbiota and high dietary tryptophan induced autoimmune activation and intestinal inflammation in healthy control mice. Finally, tryptophan enhanced RG2 growth and production of immunomodulatory metabolites.
Integrating transcriptomics, metabolomics, and microbiomics to explore the mechanism of action of bran-fried Atractylodes lancea rhizome polysaccharide in ameliorating the enhanced pharmacological effects of dextran sodium sulfate-induced colitis [0.03%] 整合转录组学、代谢组学和微生物组学探讨麸炒苍术多糖改善DSS诱导的结肠炎药效增效机制
Ding Yao,Chaoyang Ma,Chang Ke et al. Ding Yao et al.
Results: Both SALP and FALP significantly alleviated clinical signs (increased body weight, decreased DAI scores, reduced colonic pathological damage, and others), improved intestinal barrier (promoted Occludin and ZO-1 expression), and reduced intestinal inflammation (inhibited IL
Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation [0.03%] 用于肠道炎症检测和治疗的微生物生物传感器
Duolong Zhu,Jeffrey Galley,Jason Pizzini et al. Duolong Zhu et al.
Synthetic biology has enabled the development of biosensors to detect intestinal inflammation, yet few target the clinically validated biomarker of intestinal inflammation calprotectin with both diagnostic and therapeutic capabilities....Here, an optimized calprotectin biosensor is presented that leverages a zinc uptake regulator (Zur) controlled promoter coupled with a memory circuit to detect and record intestinal inflammation in vivo.
Gut microbiota modulate intestinal inflammation by endoplasmic reticulum stress-autophagy-cell death signaling axis [0.03%] 肠道微生物通过内质网应激-自噬-细胞死亡信号轴调节肠黏膜炎症
Feiyang He,Yi Zheng,Mabrouk Elsabagh et al. Feiyang He et al.
The intestinal tract, a complex organ responsible for nutrient absorption and digestion, relies heavily on a balanced gut microbiome to maintain its integrity. Disruptions to this delicate microbial ecosystem can lead to intestinal inflamma...
Empowering bacteria with light: Optogenetically engineered bacteria for light-controlled disease theranostics and regulation [0.03%] 赋予细菌光能力:用于光控疾病诊疗和调控的光遗传工程菌
Ying Yin,Xiang Cheng,Ruyan Xie et al. Ying Yin et al.
Then, special emphasis is placed on the biomedical applications of optogenetically engineered bacteria in treating diseases such as cancer, intestinal inflammation and systemic disease regulation.
Koumine mediates the generation of mtROS through the IP3R1-GRP75-VDAC1 complex to improve Citrinin induced intestinal inflammation [0.03%] 柯因通过IP3R1-GRP75-VDAC1复合物介导线粒体ROS的生成以改善 CIT 所致肠道炎症反应
Yuanyuan Li,Xiaofang Liu,Qike Zhang et al. Yuanyuan Li et al.
Conclusions: Koumine ameliorates CTN-induced intestinal inflammation by mediating mtROS production via the IP3R1-GRP75-VDAC1 complex....Koumine is a potential agent for the treatment of intestinal inflammation induced by mycotoxin exposure such as CTN.
Advances in Artificial Intelligence and Machine Learning for Precision Medicine in Necrotizing Enterocolitis and Neonatal Sepsis: A State-of-the-Art Review [0.03%] 人工智能与机器学习在新生儿坏死性小肠结肠炎和脓毒症精准医学中的进展:现状分析
Miriam Duci,Giovanna Verlato,Laura Moschino et al. Miriam Duci et al.
It is characterized by intestinal inflammation and necrosis, with significant morbidity and mortality despite advancements in neonatal care.
Q22.02024 Review Children (Basel, Switzerland). 2025 Apr 13;12(4):498. DOI:10.3390/children12040498 2025
RIPK1 ablation in T cells results in spontaneous enteropathy and TNF-driven villus atrophy [0.03%] T细胞RIPK1缺失导致自发性肠病和TNF诱导的绒毛萎缩
Jelle Huysentruyt,Wolf Steels,Mario Ruiz Pérez et al. Jelle Huysentruyt et al.
Human RIPK1 deficiency leads to early-onset intestinal inflammation and peripheral T cell imbalance, though its role in αβT cell-mediated intestinal homeostasis remains unclear.
Q16.52024 EMBO reports. 2025 Apr 30. DOI:10.1038/s44319-025-00441-5 2025
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