主题词1:intestinal+inflammation
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Bacillus subtilis Fed to Sows Promotes Intestinal Development and Regulates Mucosal Immunity in Offspring [0.03%] 饲喂母猪芽孢杆菌改善其子代仔猪肠道发育及粘膜免疫调节功能
Peng Liu,Jinjiao Zuo,Hui Lu et al. Peng Liu et al.
Diarrhea in piglets causes intestinal inflammation and epithelial damage. Weaned piglets fed with Bacillus subtilis (B.S) have enhanced intestinal mucosal immunity and reduces diarrhea in piglets.
Targeting the IL-23 Receptor Gene: A Promising Approach in Inflammatory Bowel Disease Treatment [0.03%] 靶向白细胞介素23受体基因:治疗炎症性肠病的新途径
Ploutarchos Pastras,Ioanna Aggeletopoulou,Konstantinos Papantoniou et al. Ploutarchos Pastras et al.
These cells are major contributors to intestinal inflammation and the release of pro-inflammatory cytokines. A dysregulated IL-23/Th17 axis can lead to excessive gut inflammation.
The Identification of a Glucuronyltransferase-Related Gene, GlcAT-S, with Putative Mucus Protection and Anti-Inflammatory Effects from Gut-Damaged Drosophila by Dextran Sulfate Sodium (DSS) [0.03%] 通过葡聚糖硫酸钠(DSS)建立的受损果蝇肠道中鉴定出具有潜在粘液保护和抗炎作用的糖醛酸转移酶相关基因GlcAT-S
Seung Hun Lee,Dooseon Hwang,Jang-Won Lee et al. Seung Hun Lee et al.
This study provides evidence that GlcAT-S is involved in the regulation of intestinal inflammation in Drosophila and plays a protective role against mucus disruption.
Q23.62024 Biology. 2025 May 7;14(5):513. DOI:10.3390/biology14050513 2025
Engeletin Targets Mitochondrial Dysfunction to Attenuate Oxidative Stress and Experimental Colitis in Intestinal Epithelial Cells Through AMPK/SIRT1/PGC-1α Signaling [0.03%] 恩加雷汀通过AMPK/SIRT1/PGC-1α信号靶向线粒体功能障碍以减轻肠上皮细胞的氧化应激和实验性结肠炎
Jing Li,Zhijun Geng,Lixia Yin et al. Jing Li et al.
Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is characterized by chronic intestinal inflammation and epithelial barrier disruption.
Zhiru Li,Li Zeng,Wei Huang et al. Zhiru Li et al.
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic intestinal inflammation and impaired epithelial barrier function. Emerging evidence highlights the critical role of vascular remodeling and angiogenesis in IBD pathogenesis.
AFB1 exacerbates testicular and intestinal inflammation by increasing stearoyl ethanolamide and homocysteine levels [0.03%] 黄曲霉毒素B1通过增加硬脂醇乙醇胺和同型半胱氨酸水平加重睾丸和肠道炎症
Pei-Yu Dong,Yu-Mei Chen Yan,Yue Bai et al. Pei-Yu Dong et al.
In environmental toxicology, aflatoxin B1 (AFB1) is recognized for its detrimental effects on reproductive and intestinal health. This study elucidates how AFB1-induced elevations in stearoyl ethanolamide (SEA) and homocysteine (HCY) impact...
Fumonisin B1 Exposure Causes Intestinal Tissue Damage by Triggering Oxidative Stress Pathways and Inducing Associated CYP Isoenzymes [0.03%] 伏马毒素B1通过诱导相关CYP同工酶引起肠道组织损伤及氧化应激反应
Changyu Cao,Weiping Hua,Runxi Xian et al. Changyu Cao et al.
Our results suggest that FB1 exposure causes intestinal inflammation by triggering oxidative stress pathways and modulating NXRs to induce Cytochrome P450 proteins (CYP) isoforms, leading to intestinal histopathological damage.
Q23.92024 Toxins. 2025 May 12;17(5):239. DOI:10.3390/toxins17050239 2025
Intestinal inflammation disrupts energy metabolism in layer pullets: insights into energy partitioning and intestinal metabolomic profiling [0.03%] 肠道炎症干扰产蛋鸡能量代谢:能量再分配和肠道代谢组学剖析的新见解
Qiuyu Jiang,Bingjian Huang,Simiao Chen et al. Qiuyu Jiang et al.
This study investigated the effects of intestinal inflammation on energy intake, heat production (HP), retained energy (RE) and intestinal energy metabolites in layer pullets.
Microcystis aeruginosa decreased fish appetite via inducing intestinal inflammation [0.03%] 鱼腥藻通过诱发肠道炎症降低鱼类摄食欲
Zhihao Ju,Qianqian Xiang,Tiyuan Xia et al. Zhihao Ju et al.
While it is known to cause intestinal inflammation and appetite dysregulation in fish, the relationship between these effects and their underlying molecular mechanisms remains poorly understood....This study explored the impact of M. aeruginosa-induced intestinal inflammation on fish appetite, with a focus on the underlying molecular pathways, using Pseudorasbora parva exposed to M. aeruginosa for 96 hours....These findings indicate that M. aeruginosa-induced intestinal inflammation is a potential mechanism underlying reduced appetite in fish.
Pectolinarigenin mitigates 5-FU-induced intestinal mucositis via suppressing ferroptosis through activating PPARγ/GPX4 signaling [0.03%] pektolinaringenin通过激活PPARγ / GPX4信号抑制铁死亡来缓解5-氟尿嘧啶诱导的肠黏膜炎
Xin Ge,Yi-Zhe Fan,Yanyan Deng et al. Xin Ge et al.
Results: 5-FU induced ferroptosis and intestinal inflammation both in vivo and in vitro, characterized by increased iron and ROS accumulation, reduced GSH levels, and elevated lipid peroxidation biomarkers. Histological analysis showed severe intestinal mucosal damage.
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