Alexie Ouellette,Eric P Allain,Abdullah Almaghraby et al. Alexie Ouellette et al.

Retinoic acid-related orphan receptor alpha (RORA) pathogenic variants cause intellectual developmental disorder with or without epilepsy or cerebellar ataxia (IDDECA). Herein, we present a female patient with a novel heterozygous likely pa...

Zhangwei Lv,Haobo Zhang,Yuhan Fan et al. Zhangwei Lv et al.

Previous studies have shown a complex, possibly bidirectional relationship between insomnia disorder (ID) and major depressive disorders (MDD). Neuroimaging evidence suggests the different functional connectivity (FC) of the ID and MDD patients....Independent samples t-tests identified differences in the sDFC between the ID (n=47) and IMD (n=50) groups, and Pearson's correlations examined relationships between sDFC and sleep quality, insomnia symptom severity, and depressive symptoms severity in IMD patients....In IMD group, sDFC in the left precuneus was positively correlated with depressive symptoms, while sDFC in the right putamen was negatively correlated with insomnia symptoms, and in the left putamen and right SFG, it was negatively correlated with depressive symptoms....The result provides a deeper understanding of how co-occurring depression in insomnia patients affects brain dynamics.

Anne Katrine Graudal Levinsen,Susanne Oksbjerg Dalton,Erik Jakobsen et al. Anne Katrine Graudal Levinsen et al.

Prevalences and odds ratios (ORs) with 95% confidence intervals (CI) for clinically important fatigue, pain, and insomnia by sociodemographic, clinical, and lifestyle factors were calculated....Adjusted analyses showed increased odds in women (OR fatigue 1.46, 95% CI 1.39-1.54; OR pain 1.62, 95% CI 1.55-1.70; OR insomnia 2.11, 95% CI 1.99-2.24), survivors with comorbidity (OR fatigue 2.97, 95% CI 2.78-3.18; OR pain 2.13, 95% CI 2.00-2.27; OR insomnia 1.67, 95% CI 1.55-1.80), smokers (OR fatigue...1.96, 95% CI 1.80-2.13; OR pain 1.67, 95% CI 1.55-1.81; OR insomnia 1.46, 95% CI 1.33-1.60), and survivors with obesity (OR fatigue 1.92, 95% CI 1.80-2.06; OR pain 2.21, 95% CI 2.08-2.35; OR insomnia 1.32, 95% CI 1.22-1.42)....Conclusions: Clinically important fatigue, pain, or insomnia are common in survivors of cancer, and two in five report two or all three late effects.

Youngmee Kim,Thomas C Tsai,Jennifer L Steel et al. Youngmee Kim et al.

Additionally, we will explore if both MSOS and BBTI-CC reveal a similar effect on overall sleep disturbance, insomnia severity, and health-related quality of life.

Saba Al-Youssef,Pauline Dodet,Elisabeth Groos et al. Saba Al-Youssef et al.

Ying Lu,Juan Li,Zhenzhen Cui et al. Ying Lu et al.

Data were collected using a demographic characteristics questionnaire, the mental health literacy scale, the perceived social support scale, the Chinese perceived stress scale, and the Athens insomnia scale.

Wanxia Wang,Can Li,Lu Shen et al. Wanxia Wang et al.

The research findings indicated that enrichment of jujuboside in semen zizyphi spinosae and utilization of β-glucosidase to further enhance the content of jujubogenin are of great significance for the treatment of insomnia and promoting rehabilitation.

Yu Gong,Xudong Zhang,Xiaomin Hao et al. Yu Gong et al.

After six months of acupuncture treatment, the patient's chronic diarrhea completely disappeared, and the occasional painful muscle cramps and insomnia significantly improved.

Hui Chen,Shufang Wu,Hongbin Chen et al. Hui Chen et al.

Aims: To explore the efficacy of Femoston plus escitalopram for perimenopausal women with chronic insomnia and the relevant biomarkers....Conclusion: Femoston plus escitalopram improves chronic insomnia in perimenopausal women....Serum levels of 5-HT, E2, FSH, and LH may objectively indicate the clinical severity of chronic insomnia in this population.

Elisabetta Bolognesi,Alessandra Carta,Franca Rosa Guerini et al. Elisabetta Bolognesi et al.

A significant proportion of children with Autism spectrum disorder (ASD) experience sleep issues, such as insomnia and other disorders, as assessed by the Sleep Disturbance Scale for Children.