Artesunate carbon dots for attenuating periodontal inflammation and promoting bone regenerationviaactivation of AMPK [0.03%]
基于AMPK激活的抗牙周炎和促进骨再生的青蒿素碳点疗法
Shuo Yu,Jinzhong Liu,Xiaolin Ma et al.
Shuo Yu et al.
Collectively, these findings demonstrate that ACDs effectively counteract lipopolysaccharide (LPS)-induced inflammatory responses while substantially improving bone regenerative processes through AMPK pathway modulation.
Metal-phenolic networks assisted construction of multi-layered endothelium-mimetic polyelectrolyte coating with nitric oxide generation and glycocalyx functionalization [0.03%]
金属酚类网络辅助构建具有生成一氧化氮和糖萼功能的多层血管内皮细胞模拟聚电解质涂层
Chong Chen,Chunle Zhang,Tao Yu et al.
Chong Chen et al.
Systematic in-vitro and in-vivo studies demonstrate that this coating significantly reduces platelet adhesion and activation and thrombus formation, selectively promotes endothelial cells proliferation and regulates the behaviour of smooth muscle cells, and mitigates inflammatory responses by the synergistic
Imperatorin as an activator of Nrf2/ARE in mercury-induced brain damage based on rat model study, molecular docking, and molecular simulation approaches [0.03%]
基于大鼠模型实验、分子对接及分子模拟的帝皇宁在汞致脑损伤中激活Nrf2/ARE作用的研究
Reshma Murali,Abilash Valsala Gopalakrishnan
Reshma Murali
The increase in ROS levels may lead to increased oxidative stress, mitochondrial damage, and inflammatory responses resulting in aging, and neurodegenerative and neuropsychiatric diseases.
The cGAS/STING Pathway: Friend or Foe in Regulating Cardiomyopathy [0.03%]
cGAS/STING通路在调控心肌病中的双刃剑作用
Weiyue Wang,Yuanxu Gao,Hyun Kyoung Lee et al.
Weiyue Wang et al.
Acting as a key cytosolic DNA sensor, the cGAS/STING pathway orchestrates inflammatory responses triggered by microbial infections or endogenous cellular stressors such as autophagy and apoptosis.
Dynamics of Innate Immunity in SARS-CoV-2 Infections: Exploring the Impact of Natural Killer Cells, Inflammatory Responses, Viral Evasion Strategies, and Severity [0.03%]
SARS-CoV-2感染的固有免疫动力学：探索自然杀伤细胞、炎症反应、病毒逃避策略和严重性的影响
Juan C Batista,Rodrigo DeAntonio,Sandra López-Vergès
Juan C Batista
The COVID-19 pandemic, caused by SARS-CoV-2, has had a profound impact on global health, with nearly 800 million cases reported in the Americas alone. The clinical presentation of the disease is highly variable, with approximately half of a...
Endogenous SLPI contributes to the regulation of inflammatory responses in peritoneal macrophages by modulating MMP-9 production [0.03%]
内源性SLPI通过调节MMP-9的产生来参与腹腔巨噬细胞炎症反应的调控
Mariia Tyshchenko,Natalia Pocałuń,Patrycja Kwiecińska et al.
Mariia Tyshchenko et al.
Secretory leukocyte protease inhibitor (SLPI) is described as a potent regulator of inflammation and tissue homeostasis with pleiotropic functions. It has been shown to inhibit pro-inflammatory responses in myeloid cells. However, its expre...
Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon [0.03%]
纳米塑料富集饮食暴露14天可增加斑马鱼端脑小胶质细胞免疫反应性
Robert A Mans,Hannah Kelehear,Sarah Rotschafer et al.
Robert A Mans et al.
Additionally, work in rodent models and cell culture has demonstrated that nanoplastics can induce inflammatory responses by microglia and alter astrocyte function.
Tat-GSTpi suppresses inflammatory responses by regulating ROS/MAPKs/apoptosis signaling pathways [0.03%]
Tat-GSTpi通过调节ROS/MAPKs/凋亡信号通路抑制炎症反应
Eun Ji Yeo,Min Jea Shin,Gi Soo Youn et al.
Eun Ji Yeo et al.
Glutathione S-transferase pi (GSTpi) is a phase II detoxifying enzyme that plays key roles in cellular processes. In a previous study, we have reported that cell permeable Tat-GSTpi can protect dopaminergic neurons against cell death. Howev...
HTLV-1 infection altered expression of CCR2, CXCR2, eNOS genes, and oxidative stress in aorta and heart of male mice [0.03%]
人T细胞白血病病毒1型感染影响小鼠主动脉和心脏中CCR2、CXCR2、eNOS基因表达及氧化应激反应
Saeed Niazmand,S A Rahim Rezaee,Jamshid Gholizadeh Navashenaq et al.
Saeed Niazmand et al.
HTLV-1 may contribute to inflammatory responses and oxidative stress in cardiovascular tissues. Keywords: HTLV‐1; aorta; heart; inflammation; oxidative stress.
Immunoinflammatory evidence of rheumatoid arthritis caused by COVID-19 [0.03%]
COVID-19引起类风湿性关节炎的免疫炎症证据
Zhiqiang Shao,Dan Xia,Liang Zhou et al.
Zhiqiang Shao et al.
Conclusion: There are many similarities between COVID-19 and RA in immune inflammatory responses such as cytokines and immune cells.
Meta-Analysis
Biological research. 2025 Jun 10;58(1):38. DOI:10.1186/s40659-025-00620-7 2025
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