Hyaluronan-based hydrogel achieves in situ administration of protocatechualdehyde to polarize macrophages to M2 phenotype for diabetic wound therapy [0.03%]
一种用于糖尿病伤口治疗的基于透明质酸凝胶的原儿茶醛体内递送系统
Xiaohuan Song,Dong Li,Tingting Guo et al.
Xiaohuan Song et al.
When HA-PCAE was placed onto full-thickness wounds of mice with streptozocin-induced diabetes, it resulted in inflammation attenuation, vascular development, granulation tissue generation, and collagen deposition.
Association between dietary ketogenic ratio and depressive symptoms: A population-based cross-sectional study using 2007-2018 NHANES data [0.03%]
基于2007-2018年NHANES数据的饮食生酮比例与抑郁症症状之间关系的流行病学横断面研究
Xiaoyin Zhuang,Yanni Zhan,Xia Feng et al.
Xiaoyin Zhuang et al.
We investigated the association between DKR and depressive symptoms,while exploring potential mechanisms involving inflammation and body composition.
Impact of light-dark cycle on the expression of circadian clock genes, electrocardiography, and myocardial function in mice [0.03%]
明暗周期对小鼠昼夜节律钟基因表达、心电图及心肌功能的影响
Yung-Lung Chen,Pei-Ting Lin,Ming-Yu Yang et al.
Yung-Lung Chen et al.
Mitochondrial dysfunction, fibrosis, and inflammation markers were also dysregulated.
Jee Hyuk Byun,Jaekeun Jung,Janghee Woo
Jee Hyuk Byun
CHIP-induced systemic inflammation may amplify vascular endothelial damage and complement cascade activation, which in turn promote platelet activation, fibrin deposition, and the release of neutrophil extracellular traps. These processes collectively may drive thromboembolic events.
COMMONALITIES BETWEEN FIBROTIC AND INFLAMMATORY MECHANISMS IN PROLIFERATIVE VITREORETINOPATHY AND PROLIFERATIVE DIABETIC RETINOPATHY [0.03%]
增生性玻璃体视网膜病变和增生型糖尿病视网膜病变的纤维化和炎症机制之间的共同点
Anirudh Sreenivas Bk,Sriram Simakurthy,P Mahesh Shanmugam et al.
Anirudh Sreenivas Bk et al.
Fibrosis and inflammation play central roles in both diseases....A deeper understanding of the shared microenvironmental drivers of fibrosis and inflammation in PDR and PVR may pave way for more effective and targeted therapies to prevent vision loss in these devastating retinal disorders.
NCOA4-mediated ferritinophagy promotes pyroptosis by reactive oxygen species generation in the progress of gingival inflammation [0.03%]
NCOA4介导的铁蛋白自噬通过生成活性氧促进牙龈炎症进程中的pyroptosis发生
Xinyi Ren,Zhilong Huang,Miaomiao Han et al.
Xinyi Ren et al.
Disturbance in the intracellular iron homeostasis may cause excessive reactive oxygen species (ROS) generation via Fenton reactions. Nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy, a process of autophagic degradation of ferr...
Recombinant human ADAMTS13 attenuates LPS-induced acute kidney injury and renal microangiopathy in murine advanced liver fibrosis by cleaving vWF [0.03%]
重组人ADAMTS13通过切割vWF减轻小鼠肝纤维化晚期LPS诱导的急性肾损伤和肾微血管病
Hiroyuki Masuda,Kosuke Kaji,Norihisa Nishimura et al.
Hiroyuki Masuda et al.
Concomitantly, rADAMTS13 treatment promoted angiogenesis as well as inhibited vascular inflammation in the kidney of AKI-F mice.
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