Impact of Serum Magnesium Levels on Mineral-Bone Metabolism in Non-Dialysis-Dependent Chronic Kidney Disease [0.03%]
血清镁水平对非透析依赖性慢性肾脏病矿稳态的影响
Yan-Ping Cao,Li-Ping Zhu,Hai-Jiang Ge et al.
Yan-Ping Cao et al.
The prevalence of hypomagnesemia was 0%, 6.82%, and 15.07%, while the incidence of hypermagnesemia was 5.13%, 13.64%, and 30.14% in G3, G4, and G5 stages, respectively.
Secondary Hyperparathyroidism in Primary Intestinal Lymphangiectasia: A Report of Four Cases [0.03%]
小肠淋巴管扩张症继发性甲旁亢四例报告
Dong Xue Zhang,Kun Hao,Li Zhang et al.
Dong Xue Zhang et al.
Simultaneously, hypomagnesemia was detected in three cases. Treatment with vitamin D and calcium supplements relieved symptoms, elevated serum calcium levels, and decreased parathyroid hormone (PTH) levels. In patients with PIL, evaluation of 25-hydroxyvitamin D, calcium, and PTH levels is crucial.
Case Reports
Gastroenterology research. 2025 Jun;18(3):152-158. DOI:10.14740/gr2022 2025
NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies [0.03%]
纳武单抗和伊匹木单抗联合塞利尤素治疗亚洲晚期/转移性实体瘤患者的I期剂量递增研究(NEXUS)
Joan R Choo,Santhiay Nathan Jeraj,Raghav Sundar et al.
Joan R Choo et al.
Most frequent treatment-related AEs were fatigue (5/12; G ⩾ 3 = 1), nausea (5/12; G ⩾ 3 = 0), anorexia (4/12; G ⩾ 3 = 0), transaminitis (2/12; G ⩾ 3 = 0), and hypomagnesemia (2/12; G ⩾ 3 = 0). The recommended phase II dose was SEL 60 mg once/week combined with NIVO + IPI.
The Quaternary Structure of the Sodium Pump Regulatory Complex Is Altered by Mutations of a Site Associated with Familial Hemiplegic Migraine [0.03%]
与家族性偏瘫型偏头痛相关的位点的突变可改变钠泵调节复合同四聚体结构
Jaroslava Seflova,Xuan Fang,Peter M Kekenes-Huskey et al.
Jaroslava Seflova et al.
In this study, we focused on mutations of M3 helix residue G301 that have been implicated in renal hypomagnesemia and familial hemiplegic migraine.
Late-onset Complications in a Chronic Proton Pump Inhibitor User: Electrolyte Abnormalities and a Diagnostic Approach [0.03%]
长期服用质子泵抑制剂患者的迟发并发症:电解质异常及诊断方法
Danielle H Tran,Jason R Fredrick,Radhika R Narla
Danielle H Tran
Ultimately, PPI-induced hypomagnesemia was identified as the primary driver of the patient's electrolyte abnormalities. This case serves dual teaching points....First, it underscores the importance of recognizing that refractory hypocalcemia and hypokalemia can often be linked to untreated hypomagnesemia so that timely diagnosis, effective management, and minimization of hospitalizations can be ensured....Second, this case highlights the unusual timing of symptomatic hypomagnesemia and subsequent hypocalcemia and hypokalemia despite years of prior PPI usage without prior known complications.
Case Reports
JCEM case reports. 2025 Jun 9;3(7):luaf125. DOI:10.1210/jcemcr/luaf125 2025
Serum Magnesium, Prescribed Magnesium Replacement and Cardiovascular Events in Adults with Type 2 Diabetes: A National Cohort Study in U.S. Veterans [0.03%]
美国退伍军人全国队列中的血清镁、处方补镁与2型糖尿病成人的心血管事件的关系
Ying Yin,Yan Cheng,Andrew R Zullo et al.
Ying Yin et al.
Using a new-user-design and propensity-score-matching analysis, we further related the use of prescribed oral magnesium and MACE among patients with hypomagnesemia (serum magnesium 2.3 mg/dL) were linked to higher MACE risks (HRs 1.11-1.20 for hypo-and 1.04-1.39 for hypermagnesemia, respectively) compared...Oral magnesium was prescribed to 9.7% and 0.7% of patients with hypomagnesemia and normomagnesemia, respectively....After propensity-score-matching balanced across 64 baseline characteristics, oral magnesium was associated with a lower MACE risk in 40,766 matched patients with hypomagnesemia (HR 0.89; 95%CI, 0.84-0.93), especially those on proton-pump-inhibitors or thiazides....Conclusions: In patients with T2D, both hypomagnesemia and hypermagnesemia were associated with higher one-year MACE risks compared to normomagnesemia. Prescribed oral magnesium was associated with a reduced MACE risk in hypomagnesemia but not in normomagnesemia.
Association of hypomagnesemia with chronic use of proton-pump inhibitors in patients visiting a tertiary care hospital in Peshawar, Pakistan [0.03%]
巴基斯坦白沙瓦三级护理医院就诊的低镁血症患者中质子泵抑制剂的长期使用情况调查结果分析
Khushal Nadir Hadi,Niktash Khan Hadi,Ayesha Bangash et al.
Khushal Nadir Hadi et al.
Objective: To determine the association between hypomagnesemia and chronic use of proton pump inhibitors (PPIs) among patients visiting a tertiary care hospital....Patients with hypomagnesemia had a significantly higher mean age compared to those without (48.9±12.3 vs 38.2±11.4 years, p
Ionized calcium and ionized magnesium disturbances in dogs and cats with septic peritonitis [0.03%]
脓性腹膜炎犬和猫的离子钙及镁的变化
Chiara Debie,Laure Giberto,Stéphanie Noel et al.
Chiara Debie et al.
Hypo- and hypermagnesemia were rare in dogs, while hypermagnesemia was common in cats and hypomagnesemia was not seen in cats. Dogs and cats with hypocalcemia were more likely to receive plasma.
Association between serum magnesium level and long-term prognosis of traumatic brain injury [0.03%]
血镁水平与创伤性脑损伤长期预后之间的关系
Eujene Jung,Jung-Ho Lee,Hyeng-Kyu Park
Eujene Jung
Specifically, younger patients exhibiting hypomagnesemia demonstrated a higher incidence of 6-month disability and mortality.
Assessment of bone status and bone turnover in pediatric patients with familiar hypomagnesemia with hypercalciuria and nephrocalcinosis [0.03%]
家族性低镁血症伴高钙尿和肾钙质沉着病儿科患者的骨状态和骨转换的评估
Beata Bieniaś,Anna Wieczorkiewicz-Płaza,Marcin Zaniew et al.
Beata Bieniaś et al.
Familiar hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare monogenic tubulopathy. Although some of its features are potentially harmful for skeletal homeostasis, this problem has not been systematically evaluated so far.
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