VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation [0.03%]
VPA通过调节LPS诱导的人牙髓干细胞成odontogenic分化促进 pulp再生
Zhihua Wang,Minghao Wang,Zhirong Luo et al.
Zhihua Wang et al.
In vitro, the effect of VPA on the odontogenic differentiation of human dental pulp stem cells (hDPSCs) was assessed using mineralization assays following lipopolysaccharide (LPS) exposure.
Exosomal circ_0003057 promotes osteo/odontogenic differentiation of hDPSCs by binding with EIF4A3 through upregulated parental gene ANKH [0.03%]
外泌体来源的circ_0003057通过上调其宿主基因ANKH结合EIF4A3促进人牙髓干细胞成骨/成牙本质分化
Bingtao Wang,Yuanyuan Kong,Huixian Dong et al.
Bingtao Wang et al.
Aim: Elucidating the mechanism of osteo/odontogenic differentiation of human dental pulp stem cells (hDPSCs) is crucial for advancing regenerative endodontic procedures (REPs).
circ_0002456/FUS interaction inhibits NF-κB signaling to attenuate DNA damage and inflammatory responses in hDPSCs [0.03%]
circ_0002456/FUS相互作用抑制NF-κB信号以减轻hDPSCs中的DNA损伤和炎症反应
Liecong Lin,Huixian Dong,Feng Lai et al.
Liecong Lin et al.
Loss- and gain-of-function experiments were conducted to explore the function of circ_0002456 in lipopolysaccharide (LPS)-induced DNA damage and inflammation in human dental pulp stem cells (hDPSCs).
Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis [0.03%]
骨模素通过白细胞介素-1受体1/核因子-κB信号途径调节牙髓炎的炎症反应
Yueyi Yang,Xuchen Hu,Meiling Jing et al.
Yueyi Yang et al.
It is a bioactive protein that promotes osteogenesis and suppresses the apoptosis of human dental pulp stem cells (hDPSCs). In this study, the role of OMD in pulpitis and the OMD-induced regulatory mechanism were investigated.
Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profile [0.03%]
牙龈卟啉单胞菌脂多糖对人牙髓干细胞体外行为及其炎性相关基因表达的影响
Fei He,Jingya Zhu,Xiangni Zeng et al.
Fei He et al.
Objective: The inflammatory microenvironment in pulpitis and periapical periodontitis critically impairs dental pulp stem cells (DPSCs) functionality, yet the underlying molecular mechanisms remain poorly defined. This st...
Antimicrobial 3D printed gelatin scaffolds for root canal disinfection in regenerative endodontics procedures [0.03%]
用于再生牙髓治疗根管消毒的抗菌明胶3D打印支架
Mateo Dallos Ortega,Jenny Aveyard,Raghda Magdy Abdelgawad et al.
Mateo Dallos Ortega et al.
Cytocompatibility assays using primary human dental pulp stem cells (HDPSCs) derived from 3 donors confirmed over 70% of cell viability. Furthermore, freeze-dried scaffolds demonstrated excellent shelf-life stability for at least six months.
Engineering an Integrated Bioprocess to Produce Human Dental Pulp Stem Cell-Alginate-Based Bone Organoids [0.03%]
工程化集成生物工艺生产人牙髓干细胞-藻酸盐基骨器官otypedefault
Mauricio Zamorano,Cristobal Aguilar-Gallardo,Aloyma Lugo et al.
Mauricio Zamorano et al.
Among MSCs, human dental pulp stem cells have a higher proliferation rate, shorter doubling times, lower cellular senescence, and enhanced osteogenesis than hBM-SCs under specific conditions. In addition, these cells are readily accessible and can be extracted through a subtle extraction procedure.
NAT10 Regulates LPS-Induced Inflammation via Stabilization of N4-Acetylated PTX3 mRNA in Human Dental Pulp Stem Cells [0.03%]
NAT10通过稳定人牙髓干细胞中LPS诱导的N4乙酰化PTX3 mRNA的稳定性来调节炎症反应
Zihan Ni,Luhui Cai,I-Chen Tsai et al.
Zihan Ni et al.
However, whether NAT10 affects the inflammatory response in human dental pulp stem cells (hDPSCs) remains unelucidated. In this study, elevated NAT10 expression was observed in pulpitis tissues and LPS-stimulated hDPSCs....Keywords: N-acetyltransferase 10 (NAT10); N4-acetylcytidine (ac4C); human dental pulp stem cells (hDPSCs); inflammation; lipopolysaccharide (LPS); pentraxins 3 (PTX3).
Human dental pulp stem cells attenuate airway inflammation in mice with PM2.5-induced asthma exacerbation by inhibiting the pyroptosis pathway [0.03%]
人牙髓干细胞通过抑制细胞焦亡途径减轻PM2.5诱导的哮喘小鼠气道炎症
Jianling Liu,Yuehua Chen,Zhongpeng Li et al.
Jianling Liu et al.
In this study, we evaluated the therapeutic potential and underlying mechanisms of human dental pulp stem cells (hDPSCs), a promising mesenchymal stem cell population, in mitigating airway inflammation in mice with PM2.5-induced asthma exacerbation.
Bioimplant-on-a-Chip for Facile Investigation of Periodontal Ligament Formation on Biogenic Hydroxyapatite/Ti6Al4 V Implants [0.03%]
用于研究生物活性羟基磷灰石/钛合金种植体上牙周韧带形成的人工植入物芯片
Sangbae Park,Jae Eun Kim,Juo Lee et al.
Sangbae Park et al.
The BoC consists of a dental implant, a calcium phosphate cement (CPC) insert, a nanopatterned polydimethylsiloxane (PDMS) substrate, and PDL-like tissue derived from human dental pulp stem cells (DPSCs).
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