Hepatic Glucose Uptake During Euglycemic Hyperinsulinemia Associates With Glycemia During Oral Glucose Tolerance Test [0.03%]
静血糖钳夹试验中肝脏葡萄糖摄取与口服葡萄糖耐量试验中的血糖水平相关
Miikka-Juhani Honka,Eleni Rebelos,Laura Pekkarinen et al.
Miikka-Juhani Honka et al.
Thus, this measurement provides useful information about hepatic insulin sensitivity in the more physiologic conditions of the OGTT which may be useful when studying the pathophysiology of impaired glucose tolerance and when evaluating potential treatments for impaired glycemic control.
Covalent Binding of Thioredoxin to TXNIP is Required for Diet-induced Insulin Resistance in the Liver [0.03%]
硫氧还蛋白与TXNIP的共价结合是饮食诱导的肝脏胰岛素抵抗所必需的
Sezin Dagdeviren,Megan F Hoang,Jialu Wang et al.
Sezin Dagdeviren et al.
Mice with an exchange of TXNIP Cysteine 247 for Serine (C247S) showed improved whole-body and hepatic insulin sensitivity compared to wild-type (WT) controls following an 8-week HFD. HFD-fed TXNIP C247S mouse livers also showed improved insulin signaling.
N-acetylcysteine influence on PI3K/Akt/mTOR and sphingolipid pathways in rats with MASLD induced by HFD: a promising new therapeutic purpose [0.03%]
N-乙酰半胱氨酸对HFD诱导的MASLD大鼠PI3K/Akt/mTOR和鞘脂途径的影响：一个新的潜在治疗用途
Klaudia Sztolsztener,Daniel Michalak,Adrian Chabowski
Klaudia Sztolsztener
Based on these data, NAC improved the hepatic insulin sensitivity and sphingolipid synthesis and storage, improving and restoring glucose homeostasis.
The TWIK2-mtDNA-NLRP3 inflammasome signaling in hepatic macrophages facilitates exercise-induced attenuation of hepatic inflammation and insulin resistance in db/db mice [0.03%]
TWIK2-线粒体DNA-NLRP3炎症小体信号通路促进db/db小鼠运动介导的肝炎和胰岛素抵抗缓解作用
Tan Zhang,Jingcheng Fan,Xin Wen et al.
Tan Zhang et al.
Exercise mitigated hepatic steatosis and enhanced the hepatic insulin sensitivity of db/db mice.
60-month follow-up of Long Limb vs. Standard Limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT [Internet] [0.03%]
长空肠臂与标准空肠臂罗氏缝合胃旁路术对2型糖尿病和肥胖60个月的随访：长期肢体RCT[互联网]
Saleem Ansari,Anna Kamocka,Tina Mazaheri et al.
Saleem Ansari et al.
There was no difference between the Standard Limb and Long Limb groups for postprandial active glucagon-like peptide-1 secretion (70 ± 32 pmol/L vs. 70 ± 19 pmol/L, respectively; p = 0.43), hepatic insulin sensitivity (3.4 ± 0.9 µmol/kg/min vs. 3.4 ± 1.4 µmol/kg/min, respectively; p = 0.94) and peripheral
Review
. DOI:10.3310/MYWG6289
Chronic cold exposure reprograms feeding-regulated LPL activity in white adipose tissues through hepatic ANGPTL3 and ANGPTL8 [0.03%]
慢性寒冷暴露通过肝脏ANGPTL3和ANGPTL8重新编程白色脂肪组织中的喂养调节的LPL活性
Yiliang Zhang,Shengyang Zhou,Runming Zhao et al.
Yiliang Zhang et al.
Browning improves hepatic insulin sensitivity and increases postprandial A8 expression. The feeding-increased A3/A8 overrides the feeding-suppressed A4, resulting in suppressed LPL activity in WAT by food intake.
Hepatic Estrogen Receptor Alpha Overexpression Protects Against Hepatic Insulin Resistance and MASLD [0.03%]
肝 estrogen receptor α 过表达可保护免于发生肝脏胰岛素抵抗和MASLD
Ester S Alves,Jessica D M Santos,Alessandra G Cruz et al.
Ester S Alves et al.
In HFD-fed mice, we showed a decrease in hepatic TAG content (43%) associated with improved hepatic insulin sensitivity (145%). Conclusions: From this perspective, our results prove that hepatic ERα signaling is responsible for some of the metabolic protective effects of estrogen in mice.
The Causal Role of Ectopic Fat Deposition in the Pathogenesis of Metabolic Syndrome [0.03%]
代谢综合征发病机制中异位脂肪沉积的因果作用
Joseph A M J L Janssen
Joseph A M J L Janssen
Support of a direct pathological role of ectopic fat deposition in this condition is further provided by the rapid normalization of hepatic insulin sensitivity and improvement in pancreatic β-cell function after marked reductions in ectopic fat depositions.
Growth hormone receptor in VGLUT2 or Sim1 cells regulates glycemia and insulin sensitivity [0.03%]
生长激素受体在VGLUT2或Sim1细胞中调节血糖和胰岛素敏感性
Mariana R Tavares,Willian O Dos Santos,Andressa G Amaral et al.
Mariana R Tavares et al.
Furthermore, Sim1∆GHR mice exhibited reduced endogenous glucose production and improved hepatic insulin sensitivity without alterations in whole-body or muscle glucose uptake. Sim1∆GHR mice were protected against acute but not chronic diabetogenic effects of exogenous GH administration.
The role of exosomes for sustained specific cardiorespiratory and metabolic improvements in males with type 2 diabetes after detraining [0.03%]
外泌体在2型糖尿病男性中维持特定的心血管呼吸和代谢改善作用的研究——适应期锻炼后的效果研究
Lucia Mastrototaro,Maria Apostolopoulou,Sonja Hartwig et al.
Lucia Mastrototaro et al.
The HIIT-induced changes in hepatic insulin sensitivity and ectopic lipid content were sustained after detraining in T2D and IR-NDM, whereas improvements of whole-body insulin sensitivity were abolished in T2D....Interpretation: HIIT offers sustained improvement of energy metabolism and hepatic insulin sensitivity in insulin-resistant humans, but long-term adherence is required to maintain these benefits.
耗时 0.15716 秒，为您在
48229835
条记录里面共找到 526 篇文章 [XML]