Clinical implications and application of molecular testing in the diagnosis and management of thyroid nodules in the Chinese population [0.03%]
Min Ding,Gaosong Wu,Songtao Zhang et al.
Min Ding et al.
The study assessed genetic variations in nodules and the diagnostic performance of each test, using stepwise multivariable logistic regression to explore factors affecting lymph node metastases (LNM) and tumor stage.
Frequencies and subtypes of glycophorin GYP(B-A-B) hybrids among northern Thais, Burmese, and Karen with a previous history of malaria infection: a study in the Thailand-Myanmar border area [0.03%]
Pornsawan Srichankhot,Arissara Nakapong,Anocha Sukhanpob et al.
Pornsawan Srichankhot et al.
Background: Evidence indicates that genetic variations in the GYP(B-A-B) hybrid genes are associated with protection against malaria....Our findings provide insight into genetic variations of GYP(B-A-B) hybrid alleles among populations in the Thailand-Myanmar border area.
Association of Genetic Variations in Energy Metabolism Genes with Noise-Induced Hearing Loss in a Chinese Population: A Case-Control Study [0.03%]
Bing Wang,Shanfa Yu,Jie Jiao et al.
Bing Wang et al.
Objective: This study explored the relationship between susceptibility to single-nucleotide polymorphisms (SNP) and noise-induced hearing loss (NIHL) in a population exposed to occupational noise. ...
Zijie Cheng,Haoqi Li,Dan Wu et al.
Zijie Cheng et al.
We also discuss the regulatory roles of key signaling cascades, such as PI3K-AKT, and the implications of genetic variations in enzymes involved in pyruvate metabolism. Finally, we highlight potential molecular targets within this pathway that could be leveraged for therapeutic intervention.
Macrophages promote aberrant DNA repair in multiple myeloma via the CXCL5/8-CXCR2 axis [0.03%]
巨噬细胞通过CXCL5/8-CXCR2轴促进多发性骨髓瘤中异常的DNA修复
Mengmeng Dong,Donghua He,Jinna Zhang et al.
Mengmeng Dong et al.
Furthermore, clinical data confirmed that MΦs are closely associated to the increased genetic variations of MM patients' primary cells. The study elucidates a mechanism by which MΦs regulates DNA repair in MM in the microenvironment and provides a potentially new target to counter MM progression.
Psychiatric Implications of Genetic Variations in Oligodendrocytes: Insights from hiPSC Models [0.03%]
少突胶质细胞遗传变异的精神病学意义：来自hiPSC模型的见解
Martina D&#x;Angelo,Valeria Di Stefano,Ilaria Pullano et al.
Martina D&#x;Angelo et al.
Oligodendrocyte precursor cells (OPCs) are a dynamic and heterogeneous population of glial cells essential for brain development and myelination. Beyond their well-established role in oligodendrogenesis, emerging evidence suggests that OPCs...
Deciphering the Molecular Adapting Mechanism of Lactic Acid-Tolerant Saccharomyces cerevisiae Through Genomic and Transcriptomic Analysis [0.03%]
通过对乳酸耐受性酿酒酵母的基因组和转录组分析解读其分子适应机制
Haowei Fan,Yin Wan,Wenqin Cai et al.
Haowei Fan et al.
Additionally, whole-genome re-sequencing and transcriptomic analyses were performed to identify genetic variations and differentially expressed genes between the two strains under lactic acid stress.
Xincen Xi,Xiaoxu Yang
Xincen Xi
The individual genome continuously accumulates genetic variations from a zygote [...].
Editorial
Genes. 2025 Jun 9;16(6):697. DOI:10.3390/genes16060697 2025
Clinical and Genetic Spectrum of Patients with Pediatric-Onset Epilepsy: Insights from a Single-Center Study [0.03%]
儿童期起病的癫痫患者的临床和遗传特征：单中心研究初探
Hilmi Tozkir,Semih Asikovali,Esra Bozgeyik et al.
Hilmi Tozkir et al.
Accordingly, this study aims to evaluate the clinical relevance of genetic variations detected through epilepsy panels and whole exome sequencing (WES) in pediatric-onset epilepsy patients.
Comprehensive Analysis of Genetic and Morphological Diversity in Echinochloa spp. Populations Infesting Paddy Fields in Ningxia, China [0.03%]
中国宁夏稻田中杂草
Jinhui Li,Yi Zhang,Yan Liu et al.
Jinhui Li et al.
Taken together, our study revealed significant morphological and genetic variations among barnyard grass populations, which correlated with herbicide sensitivity in Ningxia's paddy fields, underscoring the necessity for an integrated weed management approach to combat this troublesome weed species.
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