An integrated approach for genetic risk profiling of typhoid, tuberculosis, and cholera in local population of tehsil Haripur [0.03%]
哈里普尔地区当地人口的伤寒、结核病和霍乱遗传风险综合评估方法研究
Tahira Sher Afghan,Sadiq Noor Khan,Faryal Mehwish Awan et al.
Tahira Sher Afghan et al.
Despite notable progress in public health throughout the 21st century, infectious diseases like tuberculosis, typhoid, and cholera remain serious threats to global health, particularly in high-risk regions. Understanding the genetic factors...
Genetic Risk Profiling Reveals Altered Glycosyltransferase Expression as a Predictor for Patient Outcome in Neuroblastoma [0.03%]
基因风险谱分析发现神经母细胞瘤患者预后改变的糖基转移酶表达
Isabelle Ariane Bley,Stefan Behrens,Michael Spohn et al.
Isabelle Ariane Bley et al.
Background/Objectives: Neuroblastoma is a highly aggressive pediatric cancer that arises from immature nerve cells and exhibits a broad spectrum of clinical presentations. While low- and intermediate-risk neuroblastomas often have favorable...
Validation of the 5-SNP score for the prediction of venous thromboembolism in a Danish fast-track cohort of 6789 total hip and total knee arthroplasty patients [0.03%]
在一组快速通道队列中验证预测髋关节和膝关节置换术患者静脉血栓栓塞的5个SNP评分的有效性（6789名丹麦患者）
Mark J R Smeets,Pelle B Petersen,Christoffer C Jørgensen et al.
Mark J R Smeets et al.
Conclusion: These findings do not support genetic risk profiling in fast-track THA/TKA patients to predict VTE.
Redefining Precision Management of r/r Large B-Cell Lymphoma: Novel Antibodies Take on CART and BMT in the Quest for Future Treatment Strategies [0.03%]
复发/难治性大B细胞淋巴瘤精准管理的重塑：新型抗体与CAR-T和移植在未来的治疗策略中展开角逐
Reyad Dada
Reyad Dada
Clinical, pathological, and genetic risk profiling can assist in identifying which patients are most likely to benefit from these costly therapeutic options. However, new combinations may lead to new side effects, which we must learn to deal with.
Genetic Risk Profiling Associated with Recurrent Unprovoked Venous Thromboembolism [0.03%]
复发性静脉血栓栓塞的遗传风险谱分析
Hossam Hodeib,Amira Youssef,Alzahraa A Allam et al.
Hossam Hodeib et al.
Therefore, individual genetic risk profiling could be useful for the prediction of VTE recurrence....Conclusion: GRS model could be an effective and useful model in risk stratification of VTE patients, and genetic risk profiling of VTE patients could be used for the prediction of recurrence of VTE.
Xiangli Meng,Jijing Han,Li Wang et al.
Xiangli Meng et al.
Conclusion: Contemporary management of patients during pregnancy and within 12 weeks postpartum requires multidisciplinary cooperation and includes serial, noninvasive imaging, biomarker testing, and genetic risk profiling for aortopathy.
Predicting the Future of Genetic Risk Profiling of Glaucoma: A Narrative Review [0.03%]
预测遗传风险评分在青光眼未来应用的叙事综述
Xikun Han,Alex W Hewitt,Stuart MacGregor
Xikun Han
Importance: Glaucoma is the world's leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is typically asymptomatic early in the disease process, and unfortunately, many are diagnosed too late to pre...
Genetic Risk Profiling in Parkinson's Disease and Utilizing Genetics to Gain Insight into Disease-Related Biological Pathways [0.03%]
帕金森病的遗传风险分析以及利用基因了解疾病相关生物路径的方式
Ashley Hall,Sara Bandres-Ciga,Monica Diez-Fairen et al.
Ashley Hall et al.
Parkinson's disease (PD) is a complex disorder underpinned by both environmental and genetic factors. The latter only began to be understood around two decades ago, but since then great inroads have rapidly been made into deconvoluting the ...
Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease [0.03%]
神经退行性疾病中的功能基因组学、基因风险分型和细胞表型
Steven Finkbeiner
Steven Finkbeiner
Human genetics provides unbiased insights into the causes of human disease, which can be used to create a foundation for effective ways to more accurately diagnose patients, stratify patients for more successful clinical trials, discover an...
Prediction of colorectal cancer risk based on profiling with common genetic variants [0.03%]
基于常见基因变异特征谱的结直肠癌风险预测
Xue Li,Maria Timofeeva,Athina Spiliopoulou et al.
Xue Li et al.
Modeling the levels of PRS with age and sex in the general UK population shows that employing genetic risk profiling can achieve a moderate degree of risk discrimination that could be helpful to identify a subpopulation with higher CRC risk due to genetic susceptibility.
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