Spirometric and Exercise Ventilatory Predictors of Expiratory Flow-Limitation in Adults with Normal and Mildly-Obstructed Airways [0.03%]
正常及轻度气流阻塞性成人最大呼气流量减少的肺通气功能预测指标研究
Hans Christian Haverkamp,Peter Luu,Yannick Molgat-Seon et al.
Hans Christian Haverkamp et al.
Purpose: We determined the resting spirometric and exercise ventilatory variables that are predictive of exercise expiratory flow limitation (EFL) in a group of adults in whom airway function varied from mildly obstructed to above predicted values....Subjects completed an incremental exercise test. Tidal expiratory flow-volume (TEFV) curves were placed within the maximal expiratory flow-volume (MEFV) curve and %-EFL was determined based on the overlap between the TEFV and MEFV curves....A set of inputs consisting of both spirometric and exercise ventilatory variables improved the predictive ability of the models. Backward stepwise modeling, using both MRlin and MRlog, resulted in a total of seven final variables in both analyses....The final variables represented a combination of spirometric and exercise ventilatory inputs, and R2 values of 0.93 and 1.00 for MRlin and MRlog....will improve assessment of exercise ventilatory constraint.
Effects of exercise on depression and anxiety in patients with chronic pain: A systematic review and meta-analysis of randomized controlled trials [0.03%]
运动对慢性疼痛患者抑郁和焦虑的影响:随机对照试验的系统评价和meta分析
Peidong Wu,Xuxiang Chen,Shuaiwen Wang et al.
Peidong Wu et al.
Accordingly, this meta-analysis seeks to systematically evaluate the effects of exercise on anxiety and depression among individuals with chronic pain....Methods: A comprehensive search across four electronic databases was conducted to identify randomized controlled trials that assessed the impact of exercise interventions on these psychological outcomes....Furthermore, notable subgroup differences emerged concerning exercise modalities and types of chronic pain....Conclusions: The meta-analysis findings suggest that exercise interventions can alleviate anxiety and depressive symptoms among chronic pain patients....Further high-quality studies are required to refine the comparison of different exercise modalities across diverse chronic pain populations.
Proteomic profiling uncovers sexual dimorphism in the muscle response to wheel running exercise in the FLExDUX4 murine model of facioscapulohumeral muscular dystrophy [0.03%]
蛋白质组学谱分析发现FLExDUX4面肩肱肌营养不良小鼠模型在跑步运动中的性别差异响应
Yusuke Nishimura,Adam Bittel,Abhishek Jagan et al.
Yusuke Nishimura et al.
Sexual dimorphism of mitochondrial protein adaptation to exercise was uncovered specifically in FLExDUX4 mice, where females increased, but males decreased mitochondrial proteins after a 6-week of VWR.
Response to comment on "Low chronotropic response in post-myocardial infarction exercise test predicts worse prognosis in patients with preserved or mildly reduced left ventricular ejection fraction" [0.03%]
对“心肌梗死后运动试验低心率反应预测左室射血分数保留或轻度降低患者预后较差”的评论的回应
Krzysztof Smarz,Maciej Tysarowski
Krzysztof Smarz
Prehabilitation during neoadjuvant chemotherapy results in an enhanced immune response in esophageal adenocarcinoma tumors: A randomized controlled trial [0.03%]
新辅助化疗期间进行预康复可增强食管腺癌肿瘤的免疫反应:一项随机对照试验
Charles J Rayner,David B Bartlett,Sophie K Allen et al.
Charles J Rayner et al.
Prehabilitation exercise training can improve physiological function and fitness. If such improvements translate to increased immune infiltration of tumors, exercise could be prescribed as an immune adjuvant during NAC and potentially improve clinical outcomes....Methods: We assessed 22 patients with locally advanced esophageal cancer on a randomized control trial comparing 16 weeks of low-to-moderate intensity twice weekly supervised and thrice weekly home-based exercise (Prehab: n = 11) to no prehabilitation (Control: n = 11)....Secondarily, we determined relationships between changes in fitness to the exercise training and tumor-immune measures....Conclusion: We show that exercise training during NAC, which promotes higher levels of cardiorespiratory fitness than no exercise, is associated with increased frequencies of TILs and maturity of TLS. These data suggest that exercise during NAC enhances the immune system.
A single session of whole-body vibration did not affect cardiovascular autonomic recovery after a high intensity exercise in horses [0.03%]
单次全身振动对马高强度运动后心血管自主神经恢复没有影响
N A A Sales,J R G Carvalho,T O Littiere et al.
N A A Sales et al.
Aim: To investigate CAR in healthy horses during post-exercise recovery following an acute intensive exercise bout (AIEB) with WBV intervention.
Antonella Maselli,Pierpaolo Iodice,Paul Cisek et al.
Antonella Maselli et al.
Humans and other animals continuously make embodied decisions about ongoing or pending courses of action. Examples of embodied decisions include a hunting lioness's decision of which gazelle to chase and a soccer player's decision of which ...
Transferrin Saturation Is a Better Predictor Than Ferritin of Metabolic and Hemodynamic Exercise Responses in HFpEF [0.03%]
转铁蛋白饱和度比血清 ferritin 更好地预测 HFP EF 患者的运动代谢和血液动力学反应
Sujin Lee,Nicholas E Houstis,Thomas F Cunningham et al.
Sujin Lee et al.
However, the impact of iron status on hemodynamic responses to exercise and component variables of peak oxygen consumption in patients with heart failure with preserved ejection fraction (HFpEF) is unknown....Objectives: The authors sought to determine the relationship between markers of iron status and comprehensive exercise response patterns and clinical outcomes in patients with HFpEF....Methods: Cardiopulmonary exercise testing using cycle ergometry with invasive hemodynamic assessment was performed in 372 patients with HFpEF....Serum iron, transferrin saturation (Tsat), hepcidin, and ferritin were measured at the time of cardiopulmonary exercise testing, and additionally the Tsat/hepcidin ratio was used as a measure of iron homeostasis and hepcidin dysregulation, with low values reflecting inappropriate elevation in hepcidin
The potential influence of depressive symptoms on outcomes from a brief motivational intervention in patients referred to cardiac rehabilitation [0.03%]
抑郁症状对心脏康复科就诊患者短期动机干预效果的潜在影响
Ayako Tanaka,Sandeep Aggarwal,Ross Arena et al.
Ayako Tanaka et al.
baseline depressive symptoms; Center for Epidemiologic Studies Depression Scale 10 [CESD-10] >10), regression models tested intervention allocation × CESD-10 interactions on CR attendance/enrollment, intention to attend CR, beliefs and attitudes about CR, barriers, illness perceptions, social support, and exercise...Results: Depressive symptoms were associated with concerns about exercise (p = 0.005), CR barriers (p = 0.042), more threatening illness perceptions (p = 0.001), and lower social support (p < 0.001). CESD-10 scores did not independently moderate intervention outcomes (p > 0.05).
Aerobic exercise activates let-7e-5p through TP73-AS1 to inhibit the HMGB1/RAGE axis and alleviate asthma airway inflammation and remodeling [0.03%]
有氧运动通过TP73-AS1激活let-7e-5p抑制HMGB1/RAGE轴并缓解哮喘气道炎症和重塑
Dan Wang,Jing Zhao,Chunyan Yang et al.
Dan Wang et al.
Therefore, we aimed to explore the possible effects of aerobic exercise (AE) on lncRNA TP73-AS1, let-7e-5p, inflammation, and high mobility group box 1 (HMGB1)/receptor for advanced glycation end products (RAGE) in asthma mouse models....Aerobic exercise was associated with reduced airway inflammation and remodeling in asthmatic mice, and appeared to suppress TP73-AS1 expression in asthma OVA-mouse models.
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