Drew R Seeger,Brennon Schofield,Derek Besch et al. Drew R Seeger et al.

Over 50 years ago, it was also proposed to have a role in brain energy metabolism through the purine nucleotide cycle (PNC) similar to that in muscle, with, to the best of our knowledge, no follow-up studies.

Yann Moalic,Toan Bao Hung Nguyen,Jordan Hartunians et al. Yann Moalic et al.

In Thermococcales, energy metabolism genes are regulated by the sulfur-responsive transcriptional regulator SurR. In the piezophilic archaeon Thermococcus barophilus, these genes are also influenced by hydrostatic pressure....Our results show that hydrostatic pressure modulates the expression of energy metabolism genes and that SurR is essential for activating the hydrogenogenic gene cluster, even in sulfur-rich environments.

Xianzhi Qu,Buhan Liu,Duo Jin et al. Xianzhi Qu et al.

It is believed that under dual control of the mitochondrial genome (mtDNA) and the nuclear genome (nDNA) mitochondria coordinate multiple signals to alter energy metabolism under hypoxic stress....Keywords: energy metabolism remodeling; hepatocellular carcinoma; hypoxia; mitochondrial; oxidative phosphorylation; tRNA-derived fragment. Copyright © 2025 Qu, Liu, Jin, Ma, Liu, Yan, Su and Zhou.

He Li,Letian Zhang,Xingtai Li et al. He Li et al.

Aim of the study: We extracted CPP from C. pilosula and investigated the effects of CPP on energy metabolism and mitochondrial protection....Conclusion: CPP can possess and improve mitochondrial energy metabolism and bioenergetic levels. Keywords: Codonopsis pilosula (Franch.)

Wei Gao,Ruoran Chen,Huixin Tong et al. Wei Gao et al.

Purpose: This study aims to explore the therapeutic mechanisms of Ginkgo Flavone Glycosides (GFGs) delivered via liposomal nanoparticles in treating Diabetic Cardiomyopathy (DCM) by upregulating Sirtuin 1 (SIRT1) to restore energy metabolism and autophagy homeostasis....Proteomic data confirmed the beneficial effects of GFGs on diabetic cardiac energy metabolism and autophagy. Liposomal nanoparticles loaded with GFGs significantly extended drug release to 72 hours. In vitro experiments highlighted the role of SIRT1 in modulating FOSL1 and TSPAN4 expression....Proteomic sequencing further validated the regulatory role of the SIRT1/FOSL1/TSPAN4 signaling pathway in DCM and suggested that GFGs might enhance energy metabolism and autophagy in diabetic hearts by activating SIRT1....Conclusion: Liposomal nanoparticle delivery of GFGs was shown to enhance SIRT1 activation, leading to the deacetylation of FOSL1 and suppression of TSPAN4, ultimately improving energy metabolism and autophagy in DCM.

Liang Wang,Xue-Lin Li,Di Fan et al. Liang Wang et al.

Lipidomic analysis revealed significant alterations across 32 lipid classes, including a marked reduction in triglycerides and membrane-associated lipids, indicating impaired energy metabolism and disrupted cellular integrity.

Panteha Pirieh,Fereshteh Naeimpoor Panteha Pirieh

A core stoichiometric model was firstly reconstructed by integrating the versatile energy metabolism of SOB including different S-compounds oxidation as energy sources (E-sources)....Preliminary estimations on energy metabolism showed that the highest ATP (4mmol/gDw.h), NADH (2mmol/gDw.h) generations and elemental sulfur (S0) retrieval (1mmol S/gDw.h) belonged to sulfide while tetrathionate led to the least values....Inclusion of specific oxidizing reactions (where applicable) in the SOB energy metabolism led to noticeable growth enhancements for thiosulfate and tetrathionate, though sulfide reactions (SR) were found more effective....EA Limitation altered S- and N-products distribution by shifting energy metabolism towards formation of less oxidized S-products such as S0, thiosulfate and sulfite and even sulfide.

Hye-Kyung Park,Byoung Heon Kang Hye-Kyung Park

Mitochondria play a central role in cellular energy metabolism and signaling, and their dysfunction is associated with a wide range of diseases. Therefore, assessing mitochondrial function is essential for understanding their role in various cellular processes and disease progression.

Jing Xu,Youming Li,Fuzhu Pan et al. Jing Xu et al.

Proteomic analysis revealed that BXC modulates energy metabolism and inhibits cardiomyocyte ferroptosis. BXC enhanced mitochondrial energy metabolism, as evidenced by decreased ADP/ATP and AMP/ATP ratios.

İbrahim Fettahoğlu,İzel Cemre Akşahin,Buket Yeşiloğlu et al. İbrahim Fettahoğlu et al.

Background: Mitochondrial genome-encoded long non-coding RNAs (mt-LncRNAs) that play roles in regulation of energy metabolism and mitochondrial function, both crucial in mood disorder pathogenesis, yet remain poorly explored despite growing interest.