Multi-Omics Reveal Antioxidant Effects of Bardoxolone Methyl in the TSUBAKI Study [0.03%]
多组学揭示 bardoxolone 甲基在白杨研究中的抗氧化作用
Kentaro Yoshioka,Hiroto Kaneko,Waka Haruyama et al.
Kentaro Yoshioka et al.
In the Phase 2 TSUBAKI study, bardoxolone methyl, an Nrf2 activator, was shown to increase the glomerular filtration rate (GFR) in patients with diabetic kidney disease (DKD).
Effect of miR-29a-3p on renal interstitial fibrosis in diabetic kidney disease through FOXP1-mediated TGF-β1/Smad3 signaling pathway [0.03%]
miR-29a-3p通过FOXP1介导的TGF-β1/Smad3信号通路对糖尿病肾病肾间质纤维化的影响研究
Juntai Zhang,Yan Qin,Jie Liu et al.
Juntai Zhang et al.
Renal interstitial fibrosis (RIF) is a major manifestation of diabetic kidney disease (DKD).
The potential biomarker value of soluble CD36 in the treatment of diabetic kidney disease: evidence from GLP-1 and insulin interventions [0.03%]
GLP-1和胰岛素干预下可溶性CD36在糖尿病肾病治疗中的潜在生物标志价值：来自证据的启示
Wenxuan Li,Yangang Wang
Wenxuan Li
Background: Soluble CD36 (sCD36), the circulating form of the scavenger receptor CD36, plays a key role in lipid accumulation and inflammation during the progression of diabetic kidney disease (DKD), and has been proposed as a promising non-invasive biomarker.
Observational Study
Frontiers in endocrinology. 2025 May 27:16:1605631. DOI:10.3389/fendo.2025.1605631 2025
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b [0.03%]
蛇毒葛黄素通过调节SNHG10 / miR-378b抑制肾纤维化改善糖尿病肾脏疾病
Jian Hao,Hui Li,Weimin Yu
Jian Hao
Content: Diabetic kidney disease (DKD), commonly termed diabetic nephropathy (DN), is characterized by oxidative stress and renal tubular epithelial cells apoptosis driven by high glucose (HG). ...
Urine Biomarkers for Diabetic Kidney Disease Progression in Participants of the Chronic Renal Insufficiency Cohort Study [0.03%]
慢性肾病队列研究中糖尿病肾脏疾病进展的尿液生物标志物
Sarah J Schrauben,Xiaoming Zhang,Dawei Xie et al.
Sarah J Schrauben et al.
Cytoskeleton-associated protein 4 (CKAP4) affects podocyte cytoskeleton dynamics in diabetic kidney disease [0.03%]
细胞骨架相关蛋白4(CKAP4)影响糖尿病肾脏疾病中的足细胞细胞骨架动力学
Roberto Boi,Emelie Lassén,Alva Johansson et al.
Roberto Boi et al.
In diabetic kidney disease (DKD) these foot processes are effaced as a result of cytoskeleton dysregulation, a phenomenon that gradually reduces glomerular filtration.
METTL3/YTHDF3 m6A axis promotes ferroptosis in diabetic kidney disease by stabilizing TfR1 [0.03%]
METTL3/YTHDF3 m6A轴通过稳定TfR1促进糖尿病肾病中铁死亡发生
Jinmei Zhang,Xiaoping Zhou,Bin Wang et al.
Jinmei Zhang et al.
Objective: Diabetic kidney disease (DKD) is a common complication of diabetes. N6-Methyladenosine (m6A) modification is a widely studied epigenetic mechanism. Methyltransferase-like (METTL) 3 is a well-studied methyltrans...
DNA Methylation and 28-Year Incidence of Kidney Disease in Type 1 Diabetes [0.03%]
1型糖尿病受试者中DNA甲基化与28年肾病发生率的关系
Rachel G Miller,Josyf C Mychaleckyj,Suna Onengut-Gumuscu et al.
Rachel G Miller et al.
Background: Prior epigenome-wide association studies (EWAS) of DNA methylation (DNAm) and diabetic kidney disease (DKD) in type 1 diabetes (T1D) focused on advanced disease.
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway [0.03%]
宝神汤可通过PINK1/Parkin信号通路调节线粒体自噬从而缓解糖尿病肾脏疾病系膜细胞损伤
Yanyu Pang,Lei Tian,Yufei Liu et al.
Yanyu Pang et al.
Introduction: Diabetic kidney disease (DKD) progression is strongly associated with podocyte mitochondrial dysfunction. The clinically effective Chinese herbal Baoshentongluo formula (BSTL) has demonstrated significant pr...
Impact of diabetes duration and hyperglycemia on the progression of diabetic kidney disease: Insights from the KNHANES 2019-2021 [0.03%]
糖尿病病程和高血糖对糖尿病肾脏疾病进展的影响：来自2019-2021年韩国国家健康与营养调查的启示
Chang Seong Kim,Sang Heon Suh,Hong Sang Choi et al.
Chang Seong Kim et al.
Background: Diabetes is a significant risk factor for chronic kidney disease, and diabetic kidney disease (DKD) is prevalent among patients with diabetes.
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