Understanding the Crossing of Blood-Brain Barrier Using Nanocarriers: Current Trends and the Role of Physiologically Based Pharmacokinetic Modeling [0.03%]
Nazeer Abdul Azeez,Sung-Hoon Ahn
Nazeer Abdul Azeez
The perfusion-limited kinetics and permeability-limited kinetics are two key equations that describe the transport of the drug into the brain and aiding in the determination of whether surface modifications to the drug carrier are necessary to improve the permeability.
Plasma expression of antisense LncRNAs RBM5-AS1, VPS9D1-AS1 and STEAP3-AS1 as novel biomarkers for colorectal cancer diagnosis [0.03%]
Mohammadreza Karbalaei Hashemiyan,Reza Manouchehri Ardekani,Mohsen Razavizade et al.
Mohammadreza Karbalaei Hashemiyan et al.
The diagnostic performance of these lncRNAs was evaluated through receiver operating characteristic (ROC) curve analysis on Plasma samples, which also facilitated the determination of optimal cutoff values.
Early Temporal Dynamics of Gonadal Development and Sexually Dimorphic Gene Expression During Sex Differentiation in Mandarin Fish (Siniperca chuatsi) [0.03%]
Yi Rong,Yuanyuan Wang,Jinzhi Zhao et al.
Yi Rong et al.
In conclusion, by characterizing germ cell morphology and analysing expression changes in sex-related genes, we confirmed that sex determination in mandarin fish occurs before 27 dpf.
Universal design of a system for liquid-liquid microextraction: green determination of nitrate in vegetable and water samples by automated magnetic stirring-assisted dispersive liquid-liquid microextraction [0.03%]
一种用于液-液微萃取的系统通用设计：通过自动化磁力搅拌辅助离散液-液微萃取法绿色测定蔬菜和水样品中的硝酸盐含量
Jana Šandrejová,Andrea Gajdošová,Rastislav Serbin et al.
Jana Šandrejová et al.
The system was applied to the determination of NO3- in the form of an ion associate with the malachite green reagent. Under optimized conditions, the best sensitivity of determination was achieved by MSA-DLLME. The calibration graph was linear over the concentration range of 0.2-10 mg L-1 NO3-....The procedure was applied to the determination of nitrate in vegetable and water samples.
The heterogametic transition in European Bufo toads switches the sex-linkage of key vertebrate sex-determination genes and associates with a large sex-chromosome-effect [0.03%]
欧洲盘舌蟾性染色体转换改变关键脊椎动物性别决定基因的连锁方式并伴有大规模性别染色体效应
Christophe Dufresnes,Pierre-André Crochet,Beata Rozenblut-Kościsty et al.
Christophe Dufresnes et al.
Here we show that the heterogametic transition previously reported between the hybridizing toads Bufo bufo (ZW) and B. spinosus (XY) is non-homologous, potentially implicates key genes of the vertebrate sex determination cascade (SOX9, DMRT1, AMH), and is characterized by a much shorter ZW than XY segment
Association of Cumulative Social Risk and Cancer-Specific Survival Among Patients With Advanced Colorectal Cancer [0.03%]
累积社会风险与晚期结直肠癌患者癌症特异性生存率的关系
Kirbi Yelorda,Heather Day,M Katherine Arnow et al.
Kirbi Yelorda et al.
Additionally, the cross-sectional survey and linked longitudinal clinical data do not allow for determination of causality.
Highly Sensitive Square Wave Adsorptive Stripping Voltammetric Determination of Dopamine in Human Plasma Using a Cytosine-Modified Pencil Graphite Electrode [0.03%]
用人脱氧核糖核酸酶修饰的铅笔 graphite 电极测定人血浆中的多巴胺
Şeyma Korkmaz,Ayşen Demir Mülazımoğlu
Şeyma Korkmaz
The impact of varying pH values (6.4, 6.8, 7.2, 7.6, and 8.0) and phosphate buffer solution (PBS) on the DA determination was studied using the square wave voltammetry (SWV) technique....The suggested method was effectively applied to the determination of DA in human plasma serum samples to evaluate its suitability. © 2025 The Authors. Published by American Chemical Society.
Simultaneous Determination of Yeast Inhibitors 5‑HMF and Furfural in Hydrolyzed Lignocellulosic Biomass using HPLC-PDA [0.03%]
高效液相色谱-光电二极管阵列检测法同时测定水解木质纤维素生物质中的羟甲基糠醛和糠醛等抑制剂成分
Jhonatan M P Rocha,Giovano Tochetto,André L Gallina et al.
Jhonatan M P Rocha et al.
Given the need to control these substances, a methodology for the simultaneous determination of 5-HMF and furfural via high-performance liquid chromatography (HPLC) was developed and validated to monitor the formation of these unwanted byproducts directly after the hydrolysis process of the Hevea brasiliensis
Holistic transition in the anaerobic digestion: influences of multiple process controls on the methane enrichment [0.03%]
厌氧消化的系统调控对产甲烷效能的影响研究
Vignesh Natarajan,G L Karthik
Vignesh Natarajan
The modern real-time monitoring of biogas using microbial fuel cells enhances the accuracy in the determination of volatile fatty acid concentrations (> 7.87 mM), biogas productivity (0.35-0.4 L/h), and methane yield (558 mL methane/g volatile solids).
Acute Toxicity Assessment, In Vitro Antacid and Cytoprotective Effects of Root Bark Aqueous Extract of Diospyros mespiliformis on Water Immersion Stress-Induced Gastric Ulcers in Rats [0.03%]
Diospyros mespiliformis 根皮提取物的急性毒性评估、体外抗酸和细胞保护作用及其对大鼠水浸应激诱导胃溃疡的影响
Vandza Luc Vandi,André Perfusion Amang,Christophe Mezui et al.
Vandza Luc Vandi et al.
In vitro antacid activity of the extract was evaluated on artificial gastric juice by the determination of pH, neutralization time and antacid capacity. Acute toxicity of extract was evaluated.
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