Brain [18F]FDG uptake patterns in type 2 diabetes: new phenotypes relating to biomarkers of cognitive impairment [0.03%]
2型糖尿病患者的脑葡萄糖代谢模式与认知障碍生物标志物表型的关系研究
Queralt Martín-Saladich,Deborah Pareto,Rafael Simó et al.
Queralt Martín-Saladich et al.
We aimed to study these brain glucose uptake patterns in Type 2 diabetes to assess cognitive disorder risk and improve personalized management.
Preventive Effect of Probiotic Leuconostoc mesenteroides H40 Against Cognitive Disorder by Anti-Inflammatory, Synaptic Plasticity Regulation, and Antioxidant Effects [0.03%]
植物乳杆菌H40通过抗炎、调节突触可塑性和抗氧化作用预防认知障碍的预防效果
Na-Kyoung Lee,Yunjung Lee,Minhye Won et al.
Na-Kyoung Lee et al.
L. mesenteroides H40 significantly attenuated scopolamine-induced cognitive disorder in the novel object recognition and Y-maze tests in a concentration-dependent manner. L. mesenteroides H40 decreased amyloid β levels, but increased β-secretase levels.
Nan Jiang,Xiru Yu,Yuxi Yang et al.
Nan Jiang et al.
Meta-analysis for cognitive disorder DTx showed significant improvement in global cognitive function in DTx-treated participants (SMD 0.65, 95% CI 0.37-0.94), despite notable heterogeneity (I²=71.7%).
Finger motor skills and related brain regions in patients with cognitive disorder [0.03%]
认知障碍患者的指关节运动技能及其相关脑区
Shota Suzumura,Junpei Sugioka,Keita Sakurai et al.
Shota Suzumura et al.
BackgroundMotor impairment precede cognitive impairment and may be early biomarkers for dementia. We have previously reported an association between finger tapping and cognitive function; however, the link between finger motor movements and...
Korean medicine registry for cognitive disorder: A protocol for prospective observational multi-center study [0.03%]
韩国医学认知障碍登记处多中心前瞻性观察研究方案
Hanbit Jin,Do-Eun Lee,Moon Joo Cheong et al.
Hanbit Jin et al.
Objective: Despite the rapid increase in dementia and cognitive impairment incidence in Korea, research on integrative treatment for cognitive impairment using Korean medicine (KM) is still in its infancy. Thus, prospecti...
Multicenter Study
PloS one. 2025 May 15;20(5):e0323170. DOI:10.1371/journal.pone.0323170 2025
Neurocognitive Latent Space Regularization for Multi-Label Diagnosis from MRI [0.03%]
基于MRI的多标签诊断的神经认知潜在空间正则化方法
Jocasta Manasseh-Lewis,Felipe Godoy,Wei Peng et al.
Jocasta Manasseh-Lewis et al.
We apply our technique to classify brain MRIs of 156 controls, 165 cases diagnosed with mild cognitive impairment (MCI), 166 diagnosed with human immunodeficiency virus (HIV)-associated cognitive disorder (HAND), and 32 individuals diagnosed with HIV without HAND.
Protective effects of Cuscuta chinensis Lam. extract against learning and memory dysfunction induced by streptozotocin and amyloid β25-35 in vivo model [0.03%]
Dodder Seed Extracts 保护链脲佐菌素和 Aβ25-35 诱导的学习记忆障碍小鼠模型的保护效应
Ji-Hyun Kim,Hyo Jeong Seo,Byeong Wook Noh et al.
Ji-Hyun Kim et al.
(CCWE) improved cognitive disorder in a hyperglycaemic and cognitive-impaired mouse model. Hyperglycaemia was induced by streptozotocin (STZ, 50 mg/kg) and a single intracerebroventricular injection of Aβ25-35 (25 nM) was performed.
Promising clinical tools for specific Alzheimer disease diagnosis from plasma pTau217 and ApoE genotype in a cognitive disorder unit [0.03%]
在认知障碍门诊中，来自血浆pTau217和ApoE基因型的特定阿尔茨海默病诊断的临床工具展望
Lourdes Álvarez-Sánchez,Carmen Peña-Bautista,Laura Ferré-González et al.
Lourdes Álvarez-Sánchez et al.
Alternatives for AD diagnosis from blood samples are needed to develop a fully-automated early-diagnosis approach, potentially implemented in a cognitive disorder unit. Plasma p-Tau217 was determined in patients diagnosed with AD (n = 134) or non-AD (n = 132), from CSF biomarkers (Aβ42/Aβ40)....This study provided clinical tools (nomogram, double cut-off) for identifying Aβ positivity at a cognitive disorder unit, which would lead to reduce the CSF analysis.
Randomised controlled feasibility trial of online group acceptance and commitment therapy for functional cognitive disorder [0.03%]
功能认知障碍功能性认知障碍在线群体接受承诺疗法的可行性试验
Norman Poole,Sarah Cope,Serena Vanzan et al.
Norman Poole et al.
Background: Functional cognitive disorder is an increasingly recognised subtype of functional neurological disorder for which treatment options are currently limited.
Neurological adverse events associated with baclofen: A disproportionality analysis based on FDA Adverse Event Reporting System [0.03%]
基于FDA不良事件报告系统的巴氯芬相关神经性不良反应的信号检测分析
Ni Zhang,Tingting Jiang,Yanping Li et al.
Ni Zhang et al.
Unexpected significant nAE might also occur, such as intracranial hypotension (ROR: 428.52, 95% CI (355.18, 517.00); IC: 6.75, IC025 (6.56)], cognitive disorder (ROR: 2.65, 95% CI (2.21, 3.19); IC: 1.38, IC025 (1.11)], anterograde amnesia (ROR: 7.35, 95% CI (2.74, 19.72); IC: 1.69, IC025 (0.90)], metabolic
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