Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma [0.03%]
原发性和转移性食管腺癌不同临床阶段的细胞状态及相邻细胞簇
Josephine Yates,Camille Mathey-Andrews,Jihye Park et al.
Josephine Yates et al.
Esophageal adenocarcinoma (EAC) is a highly lethal cancer of the upper gastrointestinal tract with rising incidence in western populations. To decipher EAC disease progression and therapeutic response, we perform multiomic analyses of a coh...
Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages [0.03%]
磷酸化tau 217与阿尔茨海默病各阶段临床恶化的关联性分析
Judit Selma-Gonzalez,Sara Rubio-Guerra,Jesús García-Castro et al.
Judit Selma-Gonzalez et al.
However, its prognostic value across different clinical stages of AD remains unclear....The aim of this study was to assess the prognostic utility of plasma p-tau217, measured using a commercially available immunoassay, regarding clinical and functional decline across the clinical stages of AD in a cohort with up to 10 years of follow-up....Participants were classified into clinical stages 1-6 based on AD pathology status in CSF, determined by the p-tau181/Aβ1-42 ratio. The primary outcomes were cognitive decline, measured by changes in the Mini-Mental State Examination (MMSE), and progression to dementia.
Quantification of Skeletal Muscle at the First Lumbar Level for Prognosis in Amyotrophic Lateral Sclerosis [0.03%]
腰椎第一水平骨骼肌量化在肌萎缩侧索硬化预后中的作用
Yujia Cao,Baoyu Yuan,Xiuyu Jiang et al.
Yujia Cao et al.
The relationships between the quantified muscle parameters and both King's clinical stages and the Revised ALS Functional Rating Scale (ALSFRS-R) were analysed.
Evidence of mutations in tumour suppressor genes among oral cancer in Naswar, smokeless tobacco users [0.03%]
鼻烟是无烟烟草使用者口腔癌抑癌基因发生突变的证据
Fatima Iqbal,Sajjad Ahmad,Hoor Maryam et al.
Fatima Iqbal et al.
A statistically significant relation was observed between mutant TP53 protein expression and duration of Naswar use and clinical stages while difference in CDKN2A protein expression was found to be statistically significant with respect to stage only.
Multicenter Study
Acta odontologica Scandinavica. 2025 Jun 3:84:299-309. DOI:10.2340/aos.v84.43778 2025
Testicular cancer [0.03%]
睾丸癌
Julian Chavarriaga,Lucia Nappi,Alexandros Papachristofilou et al.
Julian Chavarriaga et al.
Furthermore, we explore distinct treatment approaches for seminoma and non-seminoma testicular germ cell tumours across all clinical stages and discuss post-treatment salvage options after relapse.
Predicting Recurrence in Locally Advanced Rectal Cancer Using Multitask Deep Learning and Multimodal MRI [0.03%]
基于多模态MRI和多任务深度学习预测局部晚期直肠癌复发
Zonglin Liu,Runqi Meng,Qiong Ma et al.
Zonglin Liu et al.
Multiple combinations of data from different clinical stages (pretreatment and postoperative) were input into MultiRecNet to generate different models and identify the model with optimal performance.
Multicenter Study
Radiology. Imaging cancer. 2025 May;7(3):e240359. DOI:10.1148/rycan.240359 2025
Prediction of clinical stages of cervical cancer via machine learning integrated with clinical features and ultrasound-based radiomics [0.03%]
基于临床特征和超声影像组学的机器学习预测宫颈癌分期
Maochun Zhang,Qing Zhang,Xueying Wang et al.
Maochun Zhang et al.
To investigate the prediction of a model constructed by combining machine learning (ML) with clinical features and ultrasound radiomics in the clinical staging of cervical cancer. General clinical and ultrasound data of 227 patients with ce...
Weight changes among antiretroviral therapy-naïve people living with human immunodeficiency virus in Lagos, Nigeria [0.03%]
尼日利亚拉各斯初次接受抗逆转录病毒治疗的艾滋病毒感染者体重变化情况
Oluwatosin Olaseni Odubela,Nasheeta Peer,Nkiruka Nnonyelum Odunukwe et al.
Oluwatosin Olaseni Odubela et al.
Baseline variables, including viral load ≥ 100,000 copies/ml, CD4 counts ≤ 200 cells/μL, WHO clinical stages 3 and 4, male gender, presence of anaemia and tuberculosis were associated with weight gain after ART initiation.
White Spot Lesion Treatment Options: A Systematic Review of Different Techniques for Masking These Lesions [0.03%]
关于修复白色龋齿病变的系统性综述：不同遮盖技术的疗效比较
Michela Lamorgese,Nélio Veiga,Maria J Correia et al.
Michela Lamorgese et al.
White spot lesions (WSLs) are early clinical stages of enamel demineralization, often related to orthodontic treatment or poor oral hygiene. The use of gels such as fluoride for topical application inhibits demineralization and promotes remineralization of dental tissues through various mechanisms.
Time to reoccurrence of tuberculosis and its predictors among adult HIV/AIDS patients on ART at public hospitals in East and Horro Guduru Wollega zones, West Ethiopia: a retrospective cohort study [0.03%]
特鲁德尔复发的时间及其在埃塞俄比亚西部成人HIV/AIDS患者中的预测因素：一项回顾性队列研究
Jira Wakoya Feyisa,Mebrate Dufera,Bikila Regassa Feyisa et al.
Jira Wakoya Feyisa et al.
Sex (AHR = 4.90 (95%CI:1.98, 12.53), widowed marital status (AHR = 4.00; 95%CI:1.13, 14.14), occupational status (AHR = 3.45;95%CI: 1.12, 10.64), advanced WHO clinical stages (AHR = 6.98; 95%CI: 1.71, 28.45), recurrence of opportunistic infections (AHR = 10.49; 95%CI:2.14, 51.54), low adherence to Anti-TB
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