Co-occurrence of malaria and Chagas disease in the Brazilian Amazon: the need for integrated health surveillance [0.03%]
巴西亚马逊地区马来丝虫病和查加斯病的合并感染：整合卫生监测势在必行
Izabel Cristina Dos Reis,Raquel Martins Lana,Cláudia Torres Codeço et al.
Izabel Cristina Dos Reis et al.
This study addresses the co-occurrence of malaria and Chagas disease in municipalities in the Amazon, a region characterized by geographic and climatic diversity and by socioeconomic and environmental transformations. This study aimed to id...
Empowering communities through One Health and ArtScience: An innovative approach to combat Chagas disease in endemic areas of Minas Gerais, Brazil [0.03%]
通过“One Health”和艺术科学赋能社区：巴西米纳斯吉拉斯州查加斯病流行区的一种创新应对方法
Jonathan Gonçalves-Oliveira,Catarina Macedo Lopes,Teresa C M Gonçalves et al.
Jonathan Gonçalves-Oliveira et al.
Background: Chagas disease (CD) is a neglected zoonosis that requires study through the One Health approach, as it involves various aspects of animal, environmental, and human health in its transmission cycle. This diseas...
Prevalence, knowledge, attitudes, and practices regarding Chagas disease in Guanare, Venezuela: a cross-sectional study [0.03%]
委内瑞拉瓜纳雷地区查加斯病的流行、知识、态度和行为横断面研究
Iván A Escalante-Pérez,Ana A Alviares,Óscar D Omaña-Ávila et al.
Iván A Escalante-Pérez et al.
Background: Chagas disease (CD) is endemic in 21 Latin American countries, placing approximately 75 million people at risk of infection. In Venezuela, CD has been recognized since 1919, with seroprevalence estimates reach...
The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease [0.03%]
查格斯病和恰加斯病中克鲁齐亚锥虫感染的持续性和休眠的重要性
Molly E Bunkofske,Fernando J Sanchez-Valdez,Rick L Tarleton
Molly E Bunkofske
Trypanosoma cruzi typically establishes a life-long infection in its mammalian hosts, causing the destruction of muscle tissues and ultimately resulting in potentially fatal Chagas disease. In this review, we consider the array of avoidance...
Quantitative PCR for parasitemia monitoring and preemptive therapy in patients with Chagas disease and autoimmune rheumatic disorders undergoing biologic treatment: a case series [0.03%]
定量PCR检测查加斯病及自身免疫性疾病患者生物治疗中的虫血症并进行预处理：一系列病例研究
Noemia Barbosa Carvalho,Vera Lucia Teixeira de Freitas,Nadia Emi Aikawa et al.
Noemia Barbosa Carvalho et al.
Patients with chronic Chagas disease (CD) and autoimmune rheumatic disorders (ARD) receiving immunosuppressive therapy are at risk for CD reactivation (CDR). This study monitored parasitemia over 9-121 months in six patients with CD and ARD...
Reporter genes and transgenic Trypanosoma cruzi (Kinetoplastida, Trypanosomatidae): applications for screening new drugs against Chagas disease [0.03%]
报告基因和转基因克氏锥虫(Kinetoplastida，Trypanosomatidae)：筛选查加斯病新药的用途
Daniele Santana de Sousa Oliveira,Elis Dionisio da Silva,Fábio Farias Galvão Júnior et al.
Daniele Santana de Sousa Oliveira et al.
Chagas disease is considered a public health issue, especially in Latin America. To this date, the course of the infection caused by the parasite Trypanosoma cruzi is yet to be completely understood and the conventional treatment do not pro...
Association between landscape transformation and the Chagas disease vector dynamics in a rural area with continuous surveillance and control [0.03%]
景观变化与查加斯病载体在持续监测和控制的农村地区的动态关系研究
Leonardo Sandon,Diego Weinberg,Manuel O Espinosa et al.
Leonardo Sandon et al.
Background: The Gran Chaco Region of Argentina, a hotspot for neglected tropical diseases (NTDs) including Chagas disease (CD), has undergone significant landscape transformations due to deforestation and agricultural exp...
Treatment options applied to the preclinical studies using animal models for Chagas Disease: a systematic review and meta-analysis [0.03%]
应用动物模型进行查加斯病的临床前研究治疗选项的系统评价和荟萃分析
Laura Yesenia Machaca-Luque,Mayron Antonio Candia-Puma,Brychs Milagros Roque-Pumahuanca et al.
Laura Yesenia Machaca-Luque et al.
Background: Chagas disease (CD) is a neglected tropical disease endemic to Latin America, has emerged as a global health concern due to the migration of infected individuals. With its epidemiological complexity, by diffic...
Meta-Analysis
F1000Research. 2024 Aug 5:13:885. DOI:10.12688/f1000research.150723.1 2024
Cognitive impairment in Chagas disease patients in Brazil, 2007-2021: A cross-sectional study [0.03%]
巴西2007-2021年恰加斯病患者的认知障碍：一项横断面研究
Carla J Serrano,Maria E Lisbôa-Marques,Thiago Cerqueira-Silva et al.
Carla J Serrano et al.
Introduction: Chagas Disease (CD) is frequently associated with heart failure (HF). Cognitive impairment is reported, but whether it results from CD or is a nonspecific symptom of HF is unknown. We aimed to compare cognit...
Patrícia Carla de Oliveira,Karen Dyminski Parente Ribeiro,Lilian Pereira Ferrari et al.
Patrícia Carla de Oliveira et al.
Nitric oxide (NO) plays a complex role in the pathophysiology of chronic Chagas disease (CD), contributing to both host defense and tissue damage. Thus, understanding its clinical implications may support therapeutic strategies. The objecti...
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