Therapeutic approaches for the treatment of genetic and acquired cardiovascular calcification [0.03%]
遗传性和获得性心血管钙化的治疗策略
Kevin O&#x;Brien,Hervé Husson,Yves Sabbagh
Kevin O&#x;Brien
Vascular calcification, the deposition of calcium-phosphate crystals in the vasculature, occurs through a complex interplay between cellular processes and biochemical factors that are yet to be entirely defined.
Molecular insights into the anticancer properties of dieckol: a comprehensive review [0.03%]
黛克酚抗肿瘤作用的分子机制综述
Anandakumar Pandi,Nabendu Sen,Vanitha Manickam Kalappan et al.
Anandakumar Pandi et al.
It influences critical cellular processes such as apoptosis and autophagy, often triggering mitochondrial dysfunction and lysosomal impairment to induce cancer cell death.
Integrated network toxicology and transcriptomics analysis reveals the pathogenic mechanism linking volatile organic compounds exposure to rheumatoid arthritis [0.03%]
整合网络毒理学和转录组学分析揭示了挥发性有机化合物暴露与类风湿关节炎发病机制之间的联系
Qi Cheng,Yifan Xie,Yingying Hou et al.
Qi Cheng et al.
VOCs may promote RA pathogenesis by engaging key mechanisms that include inflammatory signaling (TNF, IL-17, NF-κB), dysregulation of cellular processes (proteolysis, extracellular matrix disassembly), and altered immune responses (integrin-mediated leukocyte adhesion/migration and NK cell-mediated cytotoxicity
Cyanobacterial crowding-out effects on metabolite partitioning: Modeling 2-methylisoborneol (MIB) release dynamics and implications [0.03%]
蓝藻对代谢产物分配的排挤效应：2-甲基异丁烯醇(MIB)释放动力学及影响的模型研究
Yufan Ai,Yongnian Wu,Ming Su et al.
Yufan Ai et al.
By linking cellular processes to water quality risks, our approach enables proactive management of cyanobacterial contaminants, informing both early warning systems and operational guidance for oxidant-type optimization to prevent large-scale release of hazardous compounds from algal cells.
RNA Interference of the Genes Associated with the Invasion of Brain Tumor Cells [0.03%]
与脑肿瘤细胞侵袭有关的基因的RNA干扰作用研究
M A Dymova,O A Kartina,D V Drokov et al.
M A Dymova et al.
This review focuses on the use of this technology to influence various links in signaling pathways and, accordingly, the cellular processes associated with the invasion of glioblastoma cells.
ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance [0.03%]
ZC3H4通过调控线粒体复合物I影响前列腺基质细胞衰老、贴壁能力、黏附和上皮型肿瘤细胞的悬浮培养效应抵抗性
Teresa T Liu,Mia J Carrarini,Livianna K Myklebust et al.
Teresa T Liu et al.
Here, we utilize glycolytic restriction and pharmacologic inhibition of the mitochondrial electron transfer chain complex I to promote mitochondrial dysfunction and identify the cellular processes impacted by declining mitochondrial function in benign prostate stromal cells.
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2 [0.03%]
去泛素化酶USP14通过去泛素化KPNA2促进胃癌中c-MYC核转位及肿瘤发生发展
Jia Li,Houyi Tang,Hongbo Chang et al.
Jia Li et al.
The regulatory mechanisms in tumors are complex and diverse, encompassing a range of cellular processes such as proliferation, apoptosis, inflammation, autophagy, and drug resistance. However, the functional role of USP14 in gastric cancer remains unclear.
Region-Specific Adult Neural Stem Cell Niches of the Mediobasal Hypothalamus and Medulla Oblongata [0.03%]
中脑底和延髓的区域特异性成年神经干细胞生态位
Eriko Furube,Rena Fujii,Yuri Nambu et al.
Eriko Furube et al.
Mediobasal hypothalamic tanycytes, with proximal cell bodies facing the third ventricle and distal cellular processes toward the parenchyma, are identified as NSCs that supply various progenitor and ependymal cells.
A circular RNA derived from the ryanodine receptor 2 locus controls cardiac hypertrophy and calcium handling [0.03%]
来源于ryanodine受体2位点的环形RNA调控心脏肥大和钙稳态
Wen Pan,Hannah J Hunkler,Shambhabi Chatterjee et al.
Wen Pan et al.
Circular RNAs (circRNAs), a recently identified sub-class of non-coding RNAs, have emerged as pivotal regulators of diverse cellular processes in homeostasis and disease.
The oncogenic role of miR-155 on oral cancer progression and treatment strategies [0.03%]
miR-155在口腔癌发生发展中的致癌作用及其治疗策略研究
Alexandra Iulia Aghiorghiesei,Nikolay Mehterov,Andreea Nutu et al.
Alexandra Iulia Aghiorghiesei et al.
Studies suggest that miR-155 modulates key cellular processes such as proliferation, apoptosis, and immune response, making it a promising biomarker and potential therapeutic target.
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