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Michael Okafor,David Schmitt,Stéphane Ory et al. Michael Okafor et al.
The cell plasma membrane acts as a semi-permeable barrier essential for cellular protection and function, posing a challenge for therapeutic molecule delivery. Conventional techniques for crossing this barrier, including biophysical and bio...
Pavithra Natarajan,Jonathan D Roberts,Nitish Kunte et al. Pavithra Natarajan et al.
Elucidation of cellular entry routes can aid in the dissection of the complex intracellular trafficking and potentially allow for the manipulation of nanoparticle fate after cellular delivery (i.e., avoid lysosomal degradation).
Seung-Young Lee,Jacqueline Y Tyler,Sungwon Kim et al. Seung-Young Lee et al.
Although nanocarriers hold promise for cancer chemotherapy, their intracellular drug delivery pathways are not fully understood. In particular, the influence of nanocarrier stability on cellular uptake is still uncertain. By physically load...