Enhancing cannabinoid bioavailability: a crossover study comparing a novel self-nanoemulsifying drug delivery system and a commercial oil-based formulation [0.03%]
增强大麻素生物利用度：一种新型自纳米乳化药物传递系统与商用油基制剂比较的交叉试验研究
Vered Hermush,Nisim Mizrahi,Tal Brodezky et al.
Vered Hermush et al.
Purpose: The oral bioavailability of cannabinoids is limited due to extensive first-pass metabolism, reducing their therapeutic efficacy. This study aimed to evaluate the pharmacokinetics and relative bioavailability of c...
Enhancing Cannabinoid Bioavailability in Pain Management: The Role of Cyclodextrins [0.03%]
环糊精在疼痛管理中增强 cannabinoid 生物利用度的作用
Adriana Ribeiro,Rui Loureiro,Helena Cabral-Marques
Adriana Ribeiro
Chronic pain (CP), including pain related to cancer, affects approximately 2 billion people worldwide, significantly diminishing quality of life and imposing socio-economic burdens. Current treatments often provide limited relief and may ca...