Real-World Experience with a Commercial Circulating Tumor DNA Assay in Non-muscle-invasive Bladder Cancer [0.03%]
商业循环肿瘤DNA检测在非肌层浸润性膀胱尿路上皮癌中的实际应用体验
Betty Wang,Laura E Davis,Christopher J Weight et al.
Betty Wang et al.
Circulating tumor DNA (ctDNA) is an emerging biomarker in advanced bladder cancer, but its role in non-muscle-invasive bladder cancer (NMIBC) remains undefined.
Comment on "Oncological outcomes of patients with node positive disease following neoadjuvant chemotherapy and radical cystectomy for muscle-invasive bladder cancer: A multicenter observational study of the EAU Young Academic Urologists (YAU) urothelial carcinoma working group" [0.03%]
EAU青年泌尿外科医生协会(YAU)尿路上皮癌工作组多中心观察性研究的评论:“新辅助化疗和根治性膀胱切除术治疗肌层浸润性膀胱癌伴淋巴结阳性患者的肿瘤结局”
V D Kumar Veldi,R Sah
V D Kumar Veldi
Disparities in Access to High Volume Centers for Muscle Invasive Bladder Cancer and its Association With Treatment Patterns and Outcomes [0.03%]
肌层浸润性膀胱癌患者接受高容量医疗机构治疗的差异及其与治疗模式和预后的关系
Savannah Starr,Saam Kazemi,Precious Moman et al.
Savannah Starr et al.
Objective: To investigate access to high volume centers (HVCs) for non-metastatic muscle-invasive bladder cancer (MIBC) and assesses implications of disparities on treatment outcomes.
Exploring the chemotherapeutic potential of diosmetin ruthenium-p-cymene complex in bladder cancer treatment through the regulation of the PI3K/β-catenin/TJP1/AR signaling pathway [0.03%]
通过调节PI3K/β-catenin/TJP1/AR信号通路探讨 Diosmetin钌-p-薄荷樟脑复合物在膀胱癌治疗中的化疗潜力
Sidhanta Sil,Sakuntala Gayen,Ishita Seal et al.
Sidhanta Sil et al.
In this context, the study aimed to explore the chemotherapeutic effects of the diosmetin ruthenium-p-cymene complex in bladder cancer treatment through in vitro and in vivo approaches....Subsequently, the anticancer activity of the complex was assessed by BBN-induced bladder cancer in rats.
Nano-orchestrated magnetotactic-like navigation for electromagnetic theranostics and immune enhancement via photoautotrophic oxygenation, mild hyperthermia, and ferroptosis [0.03%]
基于光自养氧供给、微波低热和铁死亡的仿磁趋性亚毫米级电磁诊疗免疫增强导航疗法
Chi-Hung Hsiao,Yung-Wei Lin,Chia-Hung Liu et al.
Chi-Hung Hsiao et al.
In vivo, this approachsuggested significant tumor growth inhibition and prevented recurrence in bladder cancer models, highlighting its potential for robust and durable anticancer immunity.
Lifeng Zhang,Li Zhang,Shenglin Gao et al.
Lifeng Zhang et al.
Single-cell sequencing data confirm Gαi3 overexpression in bladder cancer epithelial cells. Additionally, Gαi3 is upregulated in tissues from locally treated patients and various bladder cancer cells....We observed a stronger binding affinity between the Gαi3 promoter and the transcription factor GATA4 in bladder cancer tissues. GATA4 silencing lowered Gαi3 expression, while GATA4 overexpression increased it....In vivo, Gαi3 silencing significantly hindered the growth of bladder cancer xenografts in nude mice, along with inactivation of the Akt-mTOR pathway and increased apoptosis. These results highlight Gαi3's functional role in bladder cancer progression.
Prognostic Role of Serum IL-6 Levels in Bladder Cancer Patients and Hints of its Origin [0.03%]
血清IL-6水平对膀胱癌患者的预后作用及其来源线索
Simon U Engelmann,Christoph Pickl,Maximilian Haas et al.
Simon U Engelmann et al.
In bladder cancer (BC) patients, higher IL-6 serum levels have been linked with adverse pathologic features, worse overall survival (OS) and cancer-specific survival (CSS). IL-6 is being investigated as a therapeutic target. However, concentrations in tumor-tissue are not investigated in detail....The role of IL-6 in theranostics of bladder cancer deserves more attention.
Prognostic Implications of Patients With Clinically Node Positive Bladder Cancer Undergoing Radical Cystectomy [0.03%]
根治性膀胱切除术治疗临床淋巴结阳性膀胱癌患者的预后意义
Pietro Scilipoti,Marco Moschini,Paolo Zaurito et al.
Pietro Scilipoti et al.
Introduction and objectives: Patients with clinically node-positive (cN+) bladder cancer (BCa) form a biologically and prognostically diverse group.
Computational Histology Artificial Intelligence (CHAI) Enhances Risk Stratification of High-grade Ta Non-muscle-invasive Bladder Cancer in a Multicenter Cohort: Comparison to Current European Association of Urology and American Urological Association Stratification Schemes [0.03%]
计算组织学人工智能(CHAI)增强高分级Ta非肌层浸润性膀胱癌多中心队列的风险分层:与当前欧洲泌尿外科协会和美国泌尿外科协会的分层方案进行比较
Sam S Chang,Bryn Launer,Vikram Narayan et al.
Sam S Chang et al.
Comparison of microRNA-21 expression in bladder cancer tumor with normal-appearing adjacent tissue and healthy controls [0.03%]
膀胱癌肿瘤与外观正常相邻组织及健康对照中microRNA-21的表达比较分析
Salman Soltani,Hamid Reza Rahimi,Mahdi Mottaghi et al.
Salman Soltani et al.
We aim to assess mir-21 expression in bladder cancer (BCa) and compare it to grossly normal-appearing tumor-adjacent tissue and controls.
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