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Betty Wang,Laura E Davis,Christopher J Weight et al. Betty Wang et al.
Circulating tumor DNA (ctDNA) is an emerging biomarker in advanced bladder cancer, but its role in non-muscle-invasive bladder cancer (NMIBC) remains undefined.
Savannah Starr,Saam Kazemi,Precious Moman et al. Savannah Starr et al.
Objective: To investigate access to high volume centers (HVCs) for non-metastatic muscle-invasive bladder cancer (MIBC) and assesses implications of disparities on treatment outcomes.
Sidhanta Sil,Sakuntala Gayen,Ishita Seal et al. Sidhanta Sil et al.
In this context, the study aimed to explore the chemotherapeutic effects of the diosmetin ruthenium-p-cymene complex in bladder cancer treatment through in vitro and in vivo approaches....Subsequently, the anticancer activity of the complex was assessed by BBN-induced bladder cancer in rats.
Chi-Hung Hsiao,Yung-Wei Lin,Chia-Hung Liu et al. Chi-Hung Hsiao et al.
In vivo, this approachsuggested significant tumor growth inhibition and prevented recurrence in bladder cancer models, highlighting its potential for robust and durable anticancer immunity.
Lifeng Zhang,Li Zhang,Shenglin Gao et al. Lifeng Zhang et al.
Single-cell sequencing data confirm Gαi3 overexpression in bladder cancer epithelial cells. Additionally, Gαi3 is upregulated in tissues from locally treated patients and various bladder cancer cells....We observed a stronger binding affinity between the Gαi3 promoter and the transcription factor GATA4 in bladder cancer tissues. GATA4 silencing lowered Gαi3 expression, while GATA4 overexpression increased it....In vivo, Gαi3 silencing significantly hindered the growth of bladder cancer xenografts in nude mice, along with inactivation of the Akt-mTOR pathway and increased apoptosis. These results highlight Gαi3's functional role in bladder cancer progression.
Simon U Engelmann,Christoph Pickl,Maximilian Haas et al. Simon U Engelmann et al.
In bladder cancer (BC) patients, higher IL-6 serum levels have been linked with adverse pathologic features, worse overall survival (OS) and cancer-specific survival (CSS). IL-6 is being investigated as a therapeutic target. However, concentrations in tumor-tissue are not investigated in detail....The role of IL-6 in theranostics of bladder cancer deserves more attention.
Pietro Scilipoti,Marco Moschini,Paolo Zaurito et al. Pietro Scilipoti et al.
Introduction and objectives: Patients with clinically node-positive (cN+) bladder cancer (BCa) form a biologically and prognostically diverse group.
Salman Soltani,Hamid Reza Rahimi,Mahdi Mottaghi et al. Salman Soltani et al.
We aim to assess mir-21 expression in bladder cancer (BCa) and compare it to grossly normal-appearing tumor-adjacent tissue and controls.
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