VenusMutHub: A systematic evaluation of protein mutation effect predictors on small-scale experimental data [0.03%]
VenusMutHub：对小规模实验数据上蛋白质变异效应预测器的系统评估
Liang Zhang,Hua Pang,Chenghao Zhang et al.
Liang Zhang et al.
In protein engineering, while computational models are increasingly used to predict mutation effects, their evaluations primarily rely on high-throughput deep mutational scanning (DMS) experiments that use surrogate readouts, which may not adequately capture the complex biochemical properties of interest
Biotechnological Potential of the Fusarium fujikuroi Complex From Amazonian Oenocarpus bacaba: Lipase Production and Characterization [0.03%]
亚马逊Oenocarpus bacaba中Fusarium fujikuroi复合体的生物技术潜力：脂酶生产和表征
Lucely Nogueira Dos Santos,Rafael Firmani Perna,Ana Carolina Vieira et al.
Lucely Nogueira Dos Santos et al.
The research aimed to isolate and identify fungi from Oenocarpus bacaba Mart. fruits and analyze the biochemical properties of lipase produced by the strains (maximum activity of 1750 U mL⁻¹).
Chemokines kill bacteria without triggering antimicrobial resistance by binding anionic phospholipids [0.03%]
趋化因子通过结合阴离子磷脂杀菌而不诱发抗菌药物耐药性
Sergio M Pontejo,Sophia Martinez,Allison Zhao et al.
Sergio M Pontejo et al.
The bacterial killing mechanism of chemokines and the biochemical properties that define which members of the chemokine superfamily are antimicrobial remain poorly understood.
Formation of functionally robust human neocartilage from multiple donors using highly expanded costochondral cells [0.03%]
利用高扩增的肋软骨细胞形成功能稳健的人类neo软骨组织
Takumi Takahashi,Wendy E Brown,Cecilia T Trinh et al.
Takumi Takahashi et al.
Cell morphology or gene expression levels of these cells were correlated with mechanical and biochemical properties to identify predictive markers of neocartilage functional properties. Cells from younger donors (≤3 months) expanded 8.7-fold more than cells from older donors (9-14 years).
Characterization of the temporomandibular joint of the gray wolf (Canis lupus) in health and disease [0.03%]
健康与患病下灰狼(Canis lupus)颞下颌关节的特征化研究
Katie E Peterman,Natalia Vapniarsky,Ryan P Donahue et al.
Katie E Peterman et al.
This study aimed to characterize the histological, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of the gray wolf (Canis lupus).
Some Biochemical Properties and Phytochemical Contents of Extracts of Tamarix arabica [0.03%]
阿拉伯盐烛的某些生化特性和植物化学成分含量
Afnan Ali Alshepy,Müslüm Kuzu
Afnan Ali Alshepy
Preparations of plant origin may be used directly for traditional treatment and may also be an origin for drugs used in modern medicine. Within the scope of the study, extracts were obtained from the leaf parts of the Tamarix arabica plant ...
ImmunoStruct: a multimodal neural network framework for immunogenicity prediction from peptide-MHC sequence, structure, and biochemical properties [0.03%]
ImmunoStruct：一种用于从肽-MHC序列、结构和生化性质预测免疫原性的多模态神经网络框架
Smita Krishnaswamy,Kevin Givechian,João Rocha et al.
Smita Krishnaswamy et al.
The vast majority of prediction methods only use amino acid sequence information, and do not incorporate wide-scale structure data and biochemical properties across each peptide-MHC.
Engineering Corynebacterium glutamicum with Effective Heme Supply for the Synthesis of High-Activity Hemoglobins and Myoglobins [0.03%]
具有有效血红素供应的大肠杆菌谷氨酸棒状菌工程用于合成高活性血红蛋白和肌红蛋白
Song Wang,Zirui Yin,Yue Fan et al.
Song Wang et al.
Notably, the biosynthesized Hb and Mb presented biochemical properties similar to those of their natural counterparts.
Congenital heart disease missense mutations in the TBX5 DNA-binding domain alter thermal stability and DNA-binding affinity [0.03%]
TBX5结合域错义突变改变热稳定性和DNA结合亲和力导致先天性心脏病
Alejandro Rivera-Madera,Edwin G Peña-Martínez,Jean L Messon-Bird et al.
Alejandro Rivera-Madera et al.
Missense mutations can alter the biochemical properties of proteins, including stability, structure, and function, potentially contributing to the development of multiple human diseases.
Emerging role of the cGAS-STING pathway in cardiovascular diseases: biologic function, mechanisms and targeted therapy [0.03%]
cGAS-STING信号通路在心血管疾病中的新兴作用：生物学功能、机制与靶向治疗
Junke Mou,Yuwu Chen,Xinxin Zhu et al.
Junke Mou et al.
This review elucidates the biochemical properties of cGAS and STING, as well as the mechanistic insights into the cGAS-STING pathway within the cardiovascular system, emphasizing the therapeutic potential of cGAS-STING modulators for CVD management.
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