Recent Advances in Therapeutic Potential of Dual-Acting Aromatase/COX-2 [0.03%]
aromatase / COX-2双效药物治疗潜力的最新研究进展
Ali Aliabadi,Mobina Tajdari,Sara Fakharinia et al.
Ali Aliabadi et al.
Aromatase, a crucial enzyme assigned for transforming androgen into estrogen, has a vital function in the advancement of drug-resistant breast cancers that respond to endocrine treatments. Aromatase (CYP19A1) is a monooxygenase from the cyt...
The effect of oral contraceptives on aromatase and Cox-2 expression in the endometrium of patients with idiopathic menorrhagia or adenomyosis [0.03%]
口服避孕药对特发性月经过多或子宫腺肌症患者子宫内膜芳香化酶和环氧化酶-2表达的影响
Hugo Maia Jr,Clarice Haddad,Nathaniel Pinheiro et al.
Hugo Maia Jr et al.
Background: The presence of aromatase and cyclooxygenase-2 (Cox-2) expression was investigated in the endometrium of patients with idiopathic menorrhagia or adenomyosis. The effect of oral contraceptives administered in e...
Effect of a hormone-releasing intrauterine system (Mirena(®)) on aromatase and Cox-2 expression in patients with adenomyosis submitted or not, to endometrial resection [0.03%]
激素释放型宫内节育系统(Mirena)对子宫腺肌病患者芳香化酶和环氧合酶-2表达的影响(附子宫内膜电切术疗效观察)
Hugo Maia Jr,Clarice Haddad,Julio Casoy et al.
Hugo Maia Jr et al.
Objective: To investigate the effect of a levonorgestrel-releasing intrauterine system (Mirena(®)) on aromatase and cyclooxygenase-2 (Cox-2) expression in the endometrium of patients with adenomyosis who were submitted t...
A M Brodie,Q Lu,B J Long et al.
A M Brodie et al.
We have investigated aromatase and the inducible cyclooxygenase COX-2 expression using immunocytochemistry in tumors of a series of patients with advanced breast cancer treated with aromatase inhibitors. Aromatase was expressed in 58/102 br...