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Thye Peng Ngo,Salomeh Keyhani,Samuel Leonard et al. Thye Peng Ngo et al.
Background: Few studies have reported on the prevalence and health risks associated with substance use and substance use disorder (SU/SUD) in Veterans who use long-term opioid therapy (LTOT). We leveraged health record da...
Ada Man-Choi Ho,Jennifer R Geske,Vanessa K Pazdernik et al. Ada Man-Choi Ho et al.
Following up on our earlier study of individual sex-related hormones' associations with alcohol dependence (AD), this study measured the associations between the combinations of sex-related hormones and proteins and AD in a larger sample....Conclusions: Three sex-related hormone and protein signatures appear to be associated with alcohol dependence in each sex....Peripheral levels of sex-related hormones and proteins, as well as their combinations, could be altered in people with alcohol dependence who have abstained for a few weeks compared with controls, and such differences may be sex-specific.
Heather E Webber,Douglas J Calvillo,Francesco Versace et al. Heather E Webber et al.
Contingency management (CM) relies on motivation and reward processing and is among the most effective treatments available for cocaine use disorder (CUD), yet success rates do not meet desired clinical efficacy. To improve treatment-indivi...
Mohammad Navid Ebrahimi,Sara Joushi,Sina Motamedy et al. Mohammad Navid Ebrahimi et al.
Opioid use disorder (OUD) is characterized by a persistent drive to use opioids despite significant health, mental and social consequences. Better understanding of neural processes underlying inhibitory control in OUD is needed in order to ...
Jennifer K Shah,Eloise Stanton,Allen Green et al. Jennifer K Shah et al.
Background: Necrotizing and non-necrotizing skin and soft tissue infections (SSTI) are a common and growing cause of hospitalization in individuals who use opioids. This study characterizes the changing epidemiology of op...
Aaron P Turner,Scott V Adams,Eric Hawkins et al. Aaron P Turner et al.
Veterans with alcohol dependence had increased probability for critical outcome, but only for high consumption (aRR=1.28).
Sarah I Pratt,Joelle C Ferron,Meghan Santos et al. Sarah I Pratt et al.
Introduction: Smoking rates among people with serious mental illness (SMI) are higher and quit rates are lower than in the general population. These individuals have higher levels of carcinogens in their bodies, contribut...
Shubha Bagri,Rizwana Quraishi,Ram Kumar et al. Shubha Bagri et al.
The BDNF gene Val66Met polymorphism is hypothesized to be linked with alcohol dependence syndrome (ADS)....Methods: In this cross-sectional study on treatment-seeking north Indian male ADS patients aged 18 to 60 years, alcohol dependence severity (Severity of Alcohol Dependence Questionnaire, SADQ), craving (obsessive compulsive drinking scale), and perceived stress (perceived stress scale...Almost half of the participants showed alcohol dependence with mild severity. The mean OCDS and PSS-4 scores were 26.08±9.34 and 9.08±2.4, respectively. The allelic frequency of the Val and Met alleles were 73.1% and 26.9%, respectively.
Ayesha C Sujan,Natalie E Slama,Brian T Bateman et al. Ayesha C Sujan et al.
Background: Research to date evaluating the safety of benzodizapine use during pregnancy has shown mixed results and has relied on self-report or filled prescription data, which are unlikely to capture non-medical use and...
Kevin Wenzel,Julia Thomas,Jennifer Carrano et al. Kevin Wenzel et al.
Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone (XR-N...
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