Non-Mendelian transmission of X chromosomes: mechanisms and impact on sex ratios and population dynamics in different breeding systems [0.03%]
非梅第奇尔遗传的X染色体：机制及其对不同交配制度下的性别比例和种群动态的影响
Sally Adams,Andre Pires-daSilva
Sally Adams
The non-Mendelian transmission of sex chromosomes during gametogenesis carries significant implications, influencing sex ratios and shaping evolutionary dynamics. Here we focus on known mechanisms that drive non-Mendelian inheritance of X c...
X chromosome transmission ratio distortion in Cftr +/- intercross-derived mice [0.03%]
Cftr突变小鼠中X染色体的遗传不平衡现象
Christina K Haston,Daryl G Humes,Melanie Lafleur
Christina K Haston
Background: Cystic fibrosis (CF) mice, created with a genetically engineered mutation in the Cystic fibrosis transmembrane conductance regulator (Cftr) gene, may develop intestinal plugs which limit their survival past we...
Hierarchical Bayes model for random haplotype and family effects in the transmission of fragile-X [0.03%]
脆性X染色体传递中随机单体型和家庭效应的分层贝叶斯模型
R M Huggins,D Z Loesch,G Q Qian et al.
R M Huggins et al.
A model for the transmission of the CGG repeat sequence associated with the fragile-X dynamic mutation in the FMR1 gene is developed. The model incorporates both haplotype and family effects on the expansion rate of the sequence. The result...
Transcribed sequences encoded in the region involved in contiguous deletion syndrome that comprises X-linked stapes fixation and deafness [0.03%]
包含X染色体传递的槌骨固定和聋病的缺失综合征区域中的转录序列编码区的序列克隆及测序
G Kandpal,A N Jacob,R P Kandpal
G Kandpal
We have used a direct cDNA selection protocol to isolate expressed sequences from yeast artificial chromosome clones that contain approximately 900 Kb of genomic DNA from Xq21 band that is deleted in contiguous gene syndromes comprising of ...
Transmission-ratio distortion of X chromosomes among male offspring of females with skewed X-inactivation [0.03%]
女性X染色体失活偏斜的男性后代中的X染色体传递比例扭曲现象
A K Naumova,L Olien,L M Bird et al.
A K Naumova et al.
We have begun a search for heritable variation in X-chromosome inactivation pattern in normal females to determine whether there is a genetic effect on the imprinting of X-chromosome inactivation in humans. We have performed a quantitative ...
J P Fryns,H van den Berghe
J P Fryns
Elevated serum thyroxine-binding globulin by X-chromosome transmission [0.03%]
通过X染色体传递使血清甲状腺素结合球蛋白升高
J Penhaligon,M L Wellby
J Penhaligon
A kindred with a high prevalence of hereditary serum thyroxine-binding globulin (TBG) is described. Seventeen of th 29 members of the kindred have the increased TBG trait as demonstrated by a combination of increased serum total thyroxine (...
Case Reports
Acta endocrinologica. 1982 Mar;99(3):393-6. DOI:10.1530/acta.0.0990393 1982
[Chromosome X transmission of the ornithine-carbamyl-transferase structural gene. A study of 3 families] [0.03%]
关于鸟氨酰- carbamyl 转移酶结构基因的染色体 x 传递：3个家系的研究
L Cathelineau,J M Saudubray,J Navarro et al.
L Cathelineau et al.
Elevated thyroxine-binding globulin with X-chromosome linked inheritance [0.03%]
甲状腺素结合球蛋白(X染色体传递)增高综合征
B D Buchanan,G A Hagen
B D Buchanan
A new kindred with elevated levels of serum thyroxine-binding globulin (TBG) as an inherited trait has been reported. Of the twenty-four family members tested, three males and nine females had elevated serum TBG. The pedigree was consistent...