Comparative study of Bu/Cy/ATG and Flu/Cy/ATG conditioning regimens for unrelated donor hematopoietic stem cell transplantation in severe aplastic anemia [0.03%]
评估严重获得性再生障碍性贫血患者无关供者移植时Bu/Cy/ATG和Flu/Cy/ATG预处理方案优劣的多中心回顾性研究
Liangliang Wu,Xiaowei Chen,Ming Zhou et al.
Liangliang Wu et al.
Moreover, multivariate analysis confirmed that the Bu/Cy/ATG regimen significantly reduced the risk of EBV viremia (Relative risk, RR 0.175, 95% CI: 0.026-0.717, P = 0.032) and post-transplant lymphoproliferative disorder (RR 0.031, 95% CI: 0-0.536, P = 0.012).
Jing Wang,Chunfu Zheng,Wuhan Xiao
Jing Wang
In this chapter, we describe in detail the experimental protocols for analyzing virus-host interactions in a zebrafish model in which spring viremia of carp virus (SVCV) is used as an example.
Improvement in renal function after switching from entecavir to tenofovir alafenamide in chronic hepatitis B patients with low estimated glomerular filtration rates [0.03%]
对于低估计肾小球滤过率的慢性乙肝患者的恩替卡韦换用特诺福韦艾拉酚胺改善了肾功能
Liang Wang,Shipeng Ma,Lajpat Rai Malhi et al.
Liang Wang et al.
At week 48, the incidence of low-level viremia (LLV) was 19.0% in the ETV group and 16.7% in the TAF group, respectively (p>0.05). Pairwise comparisons revealed no significant difference in the percentage of LLV between the ETV continued group and the TAF continued group at week 48, 60, and 72.
A novel killed oil adjuvanted bovine viral diarrhea virus vaccine protects from viremia and clinical manifestations: an immune response and challenge study in cattle [0.03%]
一种新型杀油佐剂牛病毒腹泻病毒疫苗可防止病毒血症和临床症状：牛免疫反应和挑战研究
Berfin Ertürk,Gizem Aytoğu,Kadir Yeşilbağ
Berfin Ertürk
Following the immunization, challenge virus (TR-72 [BVDV-1l], TCID50 106.5) was given intranasally to each group (5 animals in Group-I and II and 4 animals in Group-III), and clinical findings, hematological changes, virus shedding, side effects, and viremia were monitored for 14 days after inoculation
Optimized Sindbis Virus RNA Detection Using Novel RT-qPCR: Isolation and Characterization of Sindbis Virus from a Patient Sample [0.03%]
一种新型RT-qPCR检测登加病毒RNA的方法及其在患者样本中登加病毒分离和鉴定中的应用研究
Eveliina Ekström,Katariina Kaansalo,Phuoc T Truong Nguyen et al.
Eveliina Ekström et al.
Background: Strains of Sindbis virus (SINV) are rarely detected and isolated from human blood samples as the viremia is low and short in Pogosta disease patients.
HIV-1 envelopes from virions that persist in plasma on antiretroviral therapy show reduced susceptibility to autologous immunoglobulins and variable sensitivity to broadly neutralizing monoclonal antibodies [0.03%]
抗逆转录病毒治疗后持续存在于血浆的 HIV-1 衣壳显示出对自身免疫球蛋白的减少敏感性及对广谱单克隆抗体多变的敏感度
Savrina Manhas,Joseph P Brooker,Cory Shetler et al.
Savrina Manhas et al.
In a small subset of these individuals, this non-suppressible viremia is detected by routine clinical testing (plasma HIV-1 RNA >20 copies/ml) and has been shown to be of clonal cellular origin....The CD4 binding site mAb 3BNC117 and the Gp41-specific mAb 10E8 neutralized pseudoviruses from all donors, indicating the potential for clearance of persistent viremia in these individuals studied....Author summary: In a fraction of individuals on suppressive antiretroviral therapy (ART), episodes of persistent low-level viremia can be observed that is not attributed to ineffective ART and/or non-adherence....Previously in three individuals, we have shown that this viremia results from large HIV-1 infected T cell clones harboring replication-competent proviruses.
Insertion of the P gene of spring viremia of carp virus into the snakehead rhabdovirus genome increases virulence [0.03%]
插入草鱼春病毒P基因到鲨鱼类流行病病毒感染增强子基因组中可增加其毒性
Mariem Bessaid,Ki Hong Kim
Mariem Bessaid
Spring viremia of carp virus (SVCV) is highly lethal in common carp (Cyprinus carpio) and other cyprinid fish species.
Replication-deficient whole-virus vaccines against cytomegalovirus induce protective immunity in a guinea pig congenital infection model [0.03%]
无复制型全病毒疫苗通过 Guinea Pig 模型小鼠先天性感染模型诱导巨细胞病毒免疫反应
Mark R Schleiss,Claudia Fernández-Alarcón,Craig J Bierle et al.
Mark R Schleiss et al.
This study used the guinea pig cytomegalovirus (GPCMV) model to examine replication-deficient whole-virus vaccines for protection against maternal viremia and congenital CMV infection....Using the GPCMV model of congenital infection, this study demonstrates that two replication-impaired whole virus vaccines, though attenuated in animals, are highly immunogenic and induce preconception immunity that protects against maternal viremia and fetal infection after wild-type GPCMV challenge
Efficacy of Subcutaneous Immunoglobulin in the Postoperative Management After Pediatric Living Donor Liver Transplantation [0.03%]
儿科活体肝移植术后皮下免疫球蛋白疗效研究
Yuta Hirata,Yukihiro Sanada,Kiichiro Takadera et al.
Yuta Hirata et al.
The multivariate analysis revealed that the IVIG group and CMV viremia were a significant risk factors for bacteremia (p = 0.023 and 0.001, respectively).
A two-component cocktail of engineered DIII nanoparticles elicits broadly neutralizing antibody responses against dengue virus in mice [0.03%]
一种工程化DIII纳米颗粒双组分鸡尾酒诱导小鼠针对登革病毒的广谱中和抗体响应
Margarette C Mariano,Helen S Jung,Olivia Vergnolle et al.
Margarette C Mariano et al.
A two-component cocktail of these DIII variants elicited a broadly neutralizing response against all four DENV serotypes in mice and limited viremia in a DENV2 challenge model.
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