LncRNA TRPM2-AS promotes cell proliferation, migration, and invasion by regulating the miR-195-5p/COP1 axis in bladder cancer [0.03%]
长链非编码RNA TRPM2-AS通过调节miR-195-5p/COP1轴促进膀胱癌细胞增殖、迁移和侵袭
Changyuan Dai,Qingwen Li,Lili Wang et al.
Changyuan Dai et al.
Bladder cancer (BLCA) is one of the most frequent malignant tumors worldwide, with markedly poor prognosis when distant metastasis occurs. Long noncoding RNA (lncRNA) TRPM2-AS has been reported to play an oncogenic role in several cancers. ...
Clinical Significance and Pathogenic Mechanisms of Long Non-Coding RNA TRPM2-AS in Cancers [0.03%]
长非编码RNA TRPM2-AS在癌症中的临床意义及致病机制
Shichen Huang,Bowen Li,Huanyu Chen et al.
Shichen Huang et al.
Long non-coding RNAs (lncRNAs) are known to play vital roles in human cancers. LncRNA TRPM2-AS has been found to be upregulated in various types of cancers. The elevated levels of TRPM2-AS are associated with important clinicopathological p...
TRPM2-AS promotes ovarian cancer cell proliferation and inhibits cell apoptosis by upregulating the nearby gene TRPM2 via miR-6764-5p [0.03%]
TRPM2-AS通过上调附近基因TRPM2来促进卵巢癌细胞增殖并抑制细胞凋亡（介导微RNA-6764-5P）
Wei Zhu,Shiqin Mao,Juan Jiang
Wei Zhu
Ovarian cancer (OC) becomes a fatal gynecologic malignant cancer in females worldwide. Target therapy is a promising therapeutical choice for patients with OC, and identifying biomarkers and exploring molecular mechanisms are necessary. In ...
Long non-coding TRPM2-AS regulates fracture healing by targeting miR-545-3p/Bmp2 [0.03%]
长非编码RNA TRPM2-AS通过靶向miR-545-3p/Bmp2调节骨折愈合
Renjie Kang,Lina Huang,Teng Zeng et al.
Renjie Kang et al.
Objective: Delayed fracture healing increases the suffering of patients. An in-depth investigation of the pathogenesis of delayed fracture healing may offer new direction for the prevention and treatment. ...
LncRNA TRPM2-AS promotes endometrial carcinoma progression and angiogenesis via targeting miR-497-5p/SPP1 axis [0.03%]
长链非编码RNA TRPM2-AS通过靶向miR-497-5p/SPP1轴促进子宫内膜癌进展和血管生成
Hanbo Ma,Fengyun Weng,Xiaowen Tong et al.
Hanbo Ma et al.
Background: Anti-angiogenic therapy has become one of the effective treatment methods for tumors. Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and angiogenesis in EC. However, the un...
Exposure to ephedrine attenuates Th1/Th2 imbalance underlying OVA-induced asthma through airway epithelial cell-derived exosomal lnc-TRPM2-AS [0.03%]
麻黄碱通过气道上皮细胞分泌的长链非编码RNA lnc-TRPM2-AS介导的外泌体缓解卵清蛋白诱导的小鼠哮喘中Th1/Th2失衡作用机制研究
Yan Hu,Mengqing Wang,Jing Xie et al.
Yan Hu et al.
Although various anti-inflammatory medications, such as ephedrine, are employed to manage cough-variant asthma, their underlying mechanisms are yet to be fully understood. Recent studies suggest that exosomes derived from airway epithelial ...
Exosomal long non-coding RNA TRPM2-AS promotes angiogenesis in gallbladder cancer through interacting with PABPC1 to activate NOTCH1 signaling pathway [0.03%]
长链非编码RNA TRPM2-AS通过与PABPC1相互作用激活NOTCH1信号通路促进胆囊癌血管生成
Zhiqiang He,Yuhan Zhong,Parbatraj Regmi et al.
Zhiqiang He et al.
Background: Abnormal angiogenesis is crucial for gallbladder cancer (GBC) tumor growth and invasion, highlighting the importance of elucidating the mechanisms underlying this process. LncRNA (long non-coding RNA) is widel...
PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway [0.03%]
长链非编码RNA TRPM2-AS通过调节PDIA6促进子宫内膜癌的进程
Pengling Wang,Tianli Zhang,Nan Jiang et al.
Pengling Wang et al.
PDIA6 have been reported to be involved in a variety of cancers, however, the underlying role in endometrial cancer is still unclear. In this study, we aimed to study the function of PDIA6 in endometrial cancer. Firstly, we verified that PD...
Contribution and underlying mechanisms of lncRNA TRPM2-AS in the development and progression of human cancers [0.03%]
长链非编码RNA TRPM2-AS在人类癌症发生发展中的作用及机制研究
Fei Li,Xiuwei Chen
Fei Li
Long-stranded non-coding RNAs (lncRNAs) are RNA molecules that are longer than 200 nucleotides and do not code for proteins. They play a significant role in various biological processes, including epigenetics, cell cycle, and cell different...
lncRNA TRPM2-AS Promotes Colorectal Cancer Progression by Regulating miR-22-3p and FSTL1 [0.03%]
长链非编码RNA TRPM2-AS通过调控miR-22-3p和FSTL1促进结直肠癌进展
Yongsheng Gao,Bing Liu,Xin Liu et al.
Yongsheng Gao et al.
Background: In recent years, long noncoding RNAs (lncRNAs) relate to many biological processes, which affect the progression of tumors. Transient receptor potential melastatin 2 antisense RNA (TRPM2-AS) is reported to pla...
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