Bacteriome Signature in SARS-CoV-2-Infected Patients Correlates with Increased Gut Permeability and Systemic Inflammatory Cytokines [0.03%]
SARS-CoV-2感染患者的细菌组特征与肠道通透性增加和系统性炎症细胞因子升高有关
Larissa S Souza,Alexandre S Ferreira-Junior,Pedro C Estella et al.
Larissa S Souza et al.
The COVID-19 pandemic has highlighted the complex interplay between the gut microbiota and systemic immune responses, particularly through the gut-lung axis. Disruptions in gut microbial diversity and function-commonly referred to as dysbio...
TMPRSS2: A Key Host Factor in SARS-CoV-2 Infection and Potential Therapeutic Target [0.03%]
TMPRSS2:SARS-CoV-2感染的重要宿主因子和潜在治疗靶点
Haily Liduin Koyou,Mohd Nazil Salleh,Caroline Satu Jelemie et al.
Haily Liduin Koyou et al.
The transmembrane serine protease 2 (TMPRSS2) gene plays a crucial role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by priming the viral spike protein for membrane fusion and facilitating viral entry into host ...
SARS-Cov-2 Replication in a Blood-Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor [0.03%]
人脑微血管内皮细胞来源的血脑屏障模型中的SARS-CoV-2感染导致屏障渗透性增加及ACE2依赖性的缓激肽B1受体调节失常
Sharton Vinicius Antunes Coelho,Gabriela Lisboa E Souza,Bruno Braz Bezerra et al.
Sharton Vinicius Antunes Coelho et al.
Endothelial dysfunction plays a central role in COVID-19 pathogenesis, by affecting vascular homeostasis and worsening thromboinflammation. This imbalance may contribute to blood-brain barrier (BBB) disruption, which has been reported in lo...
Pituitary Apoplexy in a Child with Short Stature and Possible Recent SARS-CoV-2 Infection [0.03%]
疑似近期感染SARS-CoV-2的矮小儿童发生垂体卒中
Carmen Gabriela Barbu,Luminita Nicoleta Cima,Marian Andrei et al.
Carmen Gabriela Barbu et al.
Background and Clinical Significance: Pituitary apoplexy is an extremely rare condition in children and adolescents with a rapid onset due to acute hemorrhage, infarction, or both in the pituitary gland. Most frequently, pituitary apoplexy ...
Practical Challenges in the Diagnosis of SARS-CoV-2 Infection in Children [0.03%]
儿童SARS-CoV-2感染诊断的实践挑战
Alina Petronela Bouari-Coblișan,Claudia Felicia Pop,Valentina Sas et al.
Alina Petronela Bouari-Coblișan et al.
Background/Objectives: The COVID-19 pandemic, caused by SARS-CoV-2, required the rapid development of diagnostic tests. SARS-CoV-2, part of the betacoronavirus genus, shares characteristics with SARS-CoV-1, including its ability to survive ...
Novel Biomarkers for SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis [0.03%]
SARS-CoV-2感染的新生物标志物:系统回顾和荟萃分析
Sara Weronika Snopkowska Lesniak,Diego Maschio,Fernando Neria et al.
Sara Weronika Snopkowska Lesniak et al.
Background: COVID-19, caused by SARS-CoV-2, has posed significant challenge to global healthcare systems, necessitating reliable biomarkers to predict disease severity and mortality. This systematic review and meta-analysis evaluated the pr...
Population-based cross-sectional seroprevalence study of SARS-CoV-2 infection in urban residential areas in Ghana [0.03%]
加纳城市居民区冠状病毒病流行率调查研究
John H Amuasi,Anthony Afum-Adjei Awuah,Christian Obirikorang et al.
John H Amuasi et al.
Introduction: Estimates of SARS-CoV-2-specific IgG antibodies using robust designs and serological assays have been a key component in assessing and reporting the overall occurrence of COVID-19 infection burden in the gen...
Association of vaccination status and immunosuppression with mortality of SARS-CoV-2 infection in patients with fibrotic interstitial lung disease [0.03%]
接种状态和免疫抑制与纤维化间质性肺疾病患者SARS-CoV-2感染死亡率的关系
Kathryn Donohoe,Kerri A Johannson,Helene Manganas et al.
Kathryn Donohoe et al.
Background: There are limited data exploring the outcome following SARS-CoV-2 infection in fibrotic interstitial lung disease (fILD). Our goal was to determine the association of vaccination for SARS-CoV-2 with both SARS-...
Effect of SARS-CoV-2 Infection Increased the Risk of Autoimmune Disorder [0.03%]
SARS-CoV-2感染增加自身免疫性疾病的风险
Shiuan-Tzuen Su,Chun-Yu Lin,Renin Chang
Shiuan-Tzuen Su
Major Depressive Disorder in Long COVID and Exposure to Pro-Inflammatory Cytokines During Infection by SARS-CoV-2 [0.03%]
长期新冠相关的重大抑郁障碍和SARS-CoV-2感染期间接触促炎症细胞因子的关系
Hernan F Guillen-Burgos,Juan F Gálvez-Flórez,Sergio Moreno-López et al.
Hernan F Guillen-Burgos et al.
Objective: Major Depressive Disorder (MDD) is common in long COVID syndrome; however, the neurobiological mechanisms are unclear. An immune activation response has been associated with COVID-19 severity as well as in MDD....
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