Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California [0.03%]
加州镀铬厂的选址与社区的人口和社会经济因素以及血液中高含量的全氟和多氟烷基物质有关
Shiwen Li,Elizabeth Costello,Tomas K D Manea et al.
Shiwen Li et al.
Chrome plating facilities release toxic chemicals, including perfluoroalkyl and polyfluoroalkyl substances (PFAS), disproportionately affecting nearby neighborhoods. We analyzed census-tract-level demographic and socioeconomic data using th...
Comparison of Tegoprazan- and Lansoprazole-Based Fourteen-Day Triple Therapies as First-Line Treatments for Helicobacter pylori Eradication [0.03%]
雷贝拉唑和兰索拉唑为基础的14天三联疗法首次治疗幽门螺杆菌感染的疗效比较研究
Seokin Kang,Nam-Hoon Kim,Seokhyeon Jeong et al.
Seokin Kang et al.
Objectives: Tegoprazan, a novel potassium-competitive acid blocker with rapid and effective antisecretory activity, was approved for the treatment of Helicobacter pylori infections in Korea in March 2020. However, real-wo...
Suzanne Dufresne,Ramya S Kuna,Kristiana Wong et al.
Suzanne Dufresne et al.
Autophagy inhibitors are promising compounds to treat pancreatic ductal adenocarcinoma (PDA) but their efficacy in patients is unclear, highlighting a need to understand mechanisms of resistance. We used a novel approach to uncover metaboli...
Association of Telehealth Encounters With Lung Cancer Screening Consultation in the U.S.: Preliminary Results [0.03%]
美国肺癌筛查咨询中的远程医疗会话关联性：初步结果
Zhigang Xie,Sericea Stallings-Smith,Beomyoung Cho et al.
Zhigang Xie et al.
Introduction: To promote lung cancer screening among the eligible population, a crucial step involves a shared decision-making discussion between the patient and primary care provider regarding lung cancer screening servi...
Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition [0.03%]
tetramethylpyrazine通过抑制RhoA/ROCK2通路增强脑缺血再灌注损伤中的神经保护和可塑性
Yixin Zhang,Xin Zhang,Xiaocheng Shi et al.
Yixin Zhang et al.
Tetramethylpyrazine (TMP) is an active component of the Chuanxiong, effectively crosses blood-brain barrier (BBB). It exhibits neuroprotective potential in cerebral ischemia-reperfusion injury (CIRI). This study performed middle cerebral ar...
Isoleucine Binding and Regulation of Escherichia coli and Staphylococcus aureus Threonine Dehydratase (IlvA) [0.03%]
异亮氨酸结合和调节大肠杆菌和金黄色葡萄球菌苏氨酸脱水酶(IlvA)
Mi-Kyung Yun,Chitra Subramanian,Karen Miller et al.
Mi-Kyung Yun et al.
In Staphylococcus aureus, the branched-chain amino acid biosynthetic pathway provides essential intermediates for membrane biosynthesis. Threonine deaminase (IlvA) is the first enzyme in the pathway, and isoleucine feedback regulates the en...
HEALing Communities Study: Data measures for supporting a community-based intervention to reduce opioid overdose deaths [0.03%]
社区戒毒研究：支持基于社区的减少阿片类药物致死过量干预措施的数据指标
Svetla Slavova,Jennifer Villani,Daniel J Feaster et al.
Svetla Slavova et al.
Introduction: The HEALing Communities Study (HCS) tested a community-based intervention in 67 communities across Kentucky, Massachusetts, New York, and Ohio to reduce opioid overdose deaths. This paper introduces the HCS ...
Triple co-culture spheroid models of lung and ovarian carcinoma cell lines for the in vitro testing of antitumor liposomes [0.03%]
肺癌和卵巢癌细胞系的三重共培养球体模型用于抗肿瘤脂质体制剂的体外评价研究
Shrey Shah,Yongwoon Kim,Rock Pulak et al.
Shrey Shah et al.
Tumor cells cultured as spheroids have been shown to be superior to tumor cells cultured in monolayers as in vitro models of solid tumors because they exhibit features of the tumor microenvironment (TME) such as cell-cell interactions, extr...
Beyond the Surface: Mapping DDE's Metabolic Footprint on Adolescent Obesity [0.03%]
表面之下：绘制DDE在青少年肥胖代谢影响的地图
Zhenjiang Li,Shudi Pan,Brittney O Baumert et al.
Zhenjiang Li et al.
Background: Bariatric surgery is an intervention for severe obesity, leading to significant weight loss and metabolic improvements. However, the release of lipophilic chemicals accumulated in adipose tissue during weight ...
A novel synergy remediation of solubilization adsorption coupled with oxidation by cyclodextrin-magnetic biochar assisted persulfate for benzo(a)pyrene-contaminated soil [0.03%]
一种新型协同修复技术：环糊精磁性生物炭促进过硫酸盐活化耦合增溶吸附与氧化去除苯并(a)芘污染土壤中的多环芳烃污染物
Lei Wu,Yuan Gao,Zhendong Wang et al.
Lei Wu et al.
During biochar (BC) assisting persulfate (PS) in remediating organic contaminated soils, challenges include low electron transfer efficiency and a limited adsorption-oxidation interface, which hinder pollutant degradation under complex envi...
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