Astaxanthin alleviates fipronil-induced neuronal damages in male rats through modulating oxidative stress, apoptosis, and inflammatory markers [0.03%]
虾青素通过调节氧化应激、凋亡和炎症标志物缓解雄性大鼠的联苯菊酯诱导的神经损伤
Mona H Hafez,Ali H El-Far,Samar S Elblehi
Mona H Hafez
Fipronil (FPN) is an effective pesticide for veterinary and agricultural use; however, it can induce neurotoxic effects on non-target organisms after accidental exposure. Astaxanthin (AST) is a dark red carotenoid with antioxidant, anti-inf...
SIRT1-based therapy targets a gene program involved in mitochondrial turnover in a model of retinal neurodegeneration [0.03%]
基于SIRT1的疗法靶向一种参与视网膜神经退行性疾病模型中线粒体周转的基因程序
Brahim Chaqour,Jacob B Rossman,Miranda Meng et al.
Brahim Chaqour et al.
Herein, we used mice with experimental autoimmune encephalomyelitis (EAE) which recapitulates axonal and neuronal damages characteristic of ON to identify gene regulatory networks affected by constitutive ubiquitous Sirt1 expression in SIRT1 knock-in mice and wild-type mice upon targeted adeno-associated
Role of sacubitril/valsartan in modulating diabetes mediated cognitive and neuronal impairment [0.03%]
沙库必曲/缬沙坦在调节糖尿病介导的认知和神经元损伤中的作用
Mai M Al-Ashram,Manar A Nader,Ahmed R El-Sheakh
Mai M Al-Ashram
SAC/VAL administration to diabetic rats also improved neuronal damages as reflected by restored cAMP response element-binding protein (CREB), brain derived neurotrophic factor (BDNF) and pre-synaptic phosphoproteins, synapsin I and growth associated protein-43 (GAP-43) in the hippocampus of diabetic
Troglitazone as a Novel Nrf2 Activator to Attenuate Oxidative Stress and Exert Neuroprotection [0.03%]
丙吡胺作为Nrf2激活剂的新用途：减轻氧化应激和发挥神经保护作用
Linjie Zhang,Shuang Wang,Yanxia Zhang et al.
Linjie Zhang et al.
Here, we discovered that troglitazone, a clinical medication for diabetes mellitus, could serve as a Nrf2 activator to rescue neuronal damages both in vitro and in vivo.
Mitigating Early Phosphatidylserine Exposure in a Tmem30a-Dependent Way Ameliorates Neuronal Damages After Ischemic Stroke [0.03%]
以Tmem30a依赖性方式缓解早期卵磷脂酰丝氨酸暴露可减轻缺血性脑卒中后的神经元损伤
Chuanjie Wu,Jiaqi Guo,Yunxia Duan et al.
Chuanjie Wu et al.
Phosphatidylserine (PS) exposes to the outer plasma membrane after a pathological insult (e.g., stroke) but not under normal conditions whereby PS remains within the inner plasma membrane. However, the reversibility and translational potent...
Pulmonary microbiota disruption by respiratory exposure to carbon quantum dots induces neuronal damages in mice [0.03%]
通过呼吸道暴露于碳量子点破坏肺部微生物群诱导小鼠神经元损伤
Tianshu Wu,Kehan Liu,Siyuan Chen et al.
Tianshu Wu et al.
Given the fact that carbon quantum dots (CQDs) have been commercially produced in quantities, it is inevitable to make their ways into environment and interact closely with the public. Even though CQDs in the environment have been reported ...
Microglial HO-1 aggravates neuronal ferroptosis via regulating iron metabolism and inflammation in the early stage after intracerebral hemorrhage [0.03%]
小胶质细胞HO-1通过调节出血后早期铁代谢和炎症加重神经元铁死亡
Qi Liu,Ziyi Han,Tao Li et al.
Qi Liu et al.
However, the mechanisms by which HO-1 mediates the neuronal damages are still obscure.
Pathological mechanisms of glial cell activation and neurodegenerative and neuropsychiatric disorders caused by Toxoplasma gondii infection [0.03%]
由弓形虫感染引起胶质细胞活化及相关神经退行性和神经精神障碍的病理机制
Zihan Yang,Jiating Chen,Chi Zhang et al.
Zihan Yang et al.
This process results in neuronal damages that are fatal in some cases. Through inducing systemic immune responses, T. gondii infection can dramatically alter the behavior of rodents and increase the risk of various neuropsychiatric disorders in humans.
Halcinonide activates smoothened to ameliorate ischemic stroke injury [0.03%]
卤米松通过激活SMO蛋白来缓解缺血性脑卒中的损伤作用机制研究
Jingjing Liu,Wenyang Zhao,Jia Kang et al.
Jingjing Liu et al.
Methods: Halcinonide or genetic manipulation of SMO was conducted in PC12 cells to examine their impacts on oxidative or OGD/R stress, and the chemical, along with AAV-SMO or AAV-EGFP were tested in MCAO rats to investigate their potential protective effects against neuronal damages
Retraction Note to: Cardiac Arrest Alters Regional Ubiquitin Levels in Association with the Blood-Brain Barrier Breakdown and Neuronal Damages in the Porcine Brain [0.03%]
撤稿：心脏骤停通过与猪脑血脑屏障破坏和神经元损伤相关的方式改变区域泛素水平
Hari S Sharma,Ranjana Patnaik,Aruna Sharma et al.
Hari S Sharma et al.
Retraction of Publication
Molecular neurobiology. 2024 Nov 5. DOI:10.1007/s12035-024-04603-9 2024
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