Pretreatment HIV-1 Drug Resistance Among Newly Diagnosed People in Eastern Ethiopia [0.03%]
埃塞俄比亚东部新诊断HIV-1感染者的病毒准种组成和耐药性特征分析
Abdella Gemechu,Adane Mihret,Mesfin Mengesha et al.
Abdella Gemechu et al.
Background and aims: In Ethiopia, HIV-1 pretreatment drug resistance (PDR) data are limited owing to a lack of routine genotyping resistance tests. This study aimed to determine the prevalence of HIV-1 PDR mutations and g...
A bibliometric analysis of HIV-1 drug-resistant minority variants from 1999 to 2024 [0.03%]
1999至2024年HIV-1药物耐药低频突变体的文献计量分析
Chang Yan,Fengting Yu,Mengying Li et al.
Chang Yan et al.
Background: The rapid initiation of antiretroviral therapy has become an international trend, necessitating lifelong medication for all HIV patients. Sanger sequencing, as the gold standard for clinically detecting HIV dr...
The utility of integrating nanopore sequencing into routine HIV-1 drug resistance surveillance [0.03%]
将纳米孔测序整合到常规HIV-1药物耐药性监测中的实用性
Daniel Bugembe Lule,Deogratius Ssemwanga,Pontiano Kaleebu et al.
Daniel Bugembe Lule et al.
HIV continues to be a significant global public health concern. In 2022, an estimated 29.8 million people living with HIV received antiretroviral treatment (ART). From this, an estimated 10-15% of individuals living with HIV have drug-resis...
HIV-1 drug resistance and genetic transmission networks among patients with sexually transmitted HIV in Ningxia, China [0.03%]
中国宁夏性传播HIV患者的艾滋病病毒耐药和遗传传播网络分析
Jianxin Pei,Zhonglan Wu,Bingqian Si et al.
Jianxin Pei et al.
Background: Over the past decade, sexual transmission has become a dominant source of new HIV-1 infection in China. However, very few studies have been conducted to characterize the two sexual transmissions, homosexual an...
Transmitted HIV-1 Drug Resistance in Estonian Residents and Ukrainian Refugees in 2020 and 2022 [0.03%]
爱沙尼亚居民和乌克兰难民在2020年和2022年的HIV-1传播耐药性研究
Arina Šablinskaja,Hiie Soeorg,Merit Pauskar et al.
Arina Šablinskaja et al.
Objectives: We investigated the prevalence of drug resistance mutations (DRMs) in individuals newly diagnosed with HIV-1 in Estonia in 2020 and 2022, and in Ukrainian war refugees living with HIV who arrived in Estonia in...
Patterns of HIV-1 Drug Resistance Observed Through Geospatial Analysis of Routine Diagnostic Testing in KwaZulu-Natal, South Africa [0.03%]
基于地理位置的分析在南非夸祖鲁纳塔尔省HIV-1常规诊断试验中观察到的耐药模式
Lilishia Gounder,Aabida Khan,Justen Manasa et al.
Lilishia Gounder et al.
HIV-1 drug resistance (HIVDR) impedes treatment and control of HIV-1, especially in high-prevalence settings such as KwaZulu-Natal (KZN) province, South Africa. This study merged routine HIV-1 genotypic resistance test (GRT) data with Geogr...
Global, regional, and national prevalence of HIV-1 drug resistance in treatment-naive and treatment-experienced children and adolescents: a systematic review and meta-analysis [0.03%]
全球、区域和国家层面治疗初治及经治儿童和青少年HIV-1耐药的患病率：系统性综述和荟萃分析
Lingyun Ge,Yinsong Luo,Xiaorui Li et al.
Lingyun Ge et al.
Background: Despite significant reductions in mother-to-child HIV-1 transmission risks due to the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 drug resistance (HIVDR) in treatment-...
Performance of an in-house multiplex PCR assay for HIV-1 drug resistance testing - A cheaper alternative [0.03%]
一种用于HIV-1药物耐药性检测的多重PCR检测试剂盒的效果：一个廉价的选择
Tumelo L Fortuin,Paballo Nkone,Allison Glass et al.
Tumelo L Fortuin et al.
Background: Currently, most HIV drug resistance PCR assays amplify the protease-reverse transcriptase (PR-RT) fragment separately from the integrase (IN) fragment. The aim of this study was to develop a multiplex PCR assa...
Thomas Lhossein,Karine Sylvain,Véronique Descamps et al.
Thomas Lhossein et al.
HIV evolution and variability around the world requires special monitoring of the viral strains in infected people. High-throughput HIV sequencing and drug resistance testing techniques have become routinely available over the last few year...
Changes in Primary HIV-1 Drug Resistance Due to War Migration from Eastern Europe [0.03%]
来自东欧战争难民的HIV-1初始药物耐药性变化
Andrzej Załęski,Agnieszka Lembas,Tomasz Dyda et al.
Andrzej Załęski et al.
In recent years, especially as a result of war in Ukraine, enormous movements of migration to Poland from eastern European countries have been reported, including people living with Human Immunodeficiency Virus (HIV). We have conducted mult...
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