Astaxanthin mitigates radiation-induced erectile dysfunction: protective effects on corpus cavernosum in a rat model [0.03%]
虾青素通过保护海绵体组织预防放射性阴茎勃起功能障碍的小鼠模型研究
Gunal Ozgur,Bahadir Sahin,Beste Melek Atasoy et al.
Gunal Ozgur et al.
The objective of this study was to evaluate the effects of ionizing radiation (iR) on corpus cavernosum and the potential of astaxanthin (AST) in preventing radiation-induced erectile dysfunction (RiED).
Jiangping Deng,Alexandra Triko,Alberto Colombo et al.
Jiangping Deng et al.
Background: Erectile dysfunction (ED) is a serious medical condition that impacts quality of life. An underlying cause is loss of cavernous nerve (CN) innervation, which initiates remodeling of the corpora cavernosa of th...
Discovery of Natural Phosphodiesterase 5 Inhibitors from Dalbergia cochinchinensis Pierre Leaves Using LC-QTOF-MS2 [0.03%]
Ruttanaporn Chantakul,Corine Girard,François Senejoux et al.
Ruttanaporn Chantakul et al.
PDE5 is directly associated with erectile dysfunction disease. Currently, many studies aim to find natural PDE5 inhibitors as an alternative to commercial drugs. This study is the first to demonstrate that the ethanolic leaf extract of D. cochinchinensis exhibits potent PDE5-inhibitory activity.
Critical Insights on "Patient Experiences and Expectations Regarding Erectile Dysfunction Education Prior to Rectal Cancer Surgery: A Qualitative Study" [0.03%]
关于直肠癌手术前男性患者求知欲和预期体验的批判性见解——一项定性研究
Bilal Ahmad,Noaman Khan,Abdur Rehman et al.
Bilal Ahmad et al.
Real-time transrectal ultrasound-guided transurethral resection of prostate cyst: a novel technique and initial clinical experience [0.03%]
实时经直肠超声引导的经尿道前列腺囊肿切除术：一项新技术及初步临床应用体验
Fu-Xiang Lin,Fu Feng,Zhan-Ping Xu
Fu-Xiang Lin
No significant complications like urinary incontinence or erectile dysfunction were observed, and no cyst recurrences were noted. Real-time TRUS-guided TURP-Cyst is safe and effective, offering precise localization, minimal trauma, and significant LUTS improvement.
Chronic administration of the hydrogen sulfide prodrug SG1002 partially protects against erectile dysfunction resulting from long-term androgen deprivation [0.03%]
给药氢硫酸剂SG1002可部分缓解长期雄激素剥夺导致的勃起功能障碍
Colin M Ihrig,Clifford J Pierre,Tooyib A Azeez et al.
Colin M Ihrig et al.
Aims: Androgen deprivation therapy is a common treatment strategy for prostate cancer, although erectile dysfunction (ED) often coincides as an undesirable side-effect.
Efficacy of low-intensity extracorporeal shock wave therapy for erectile dysfunction: updated meta-analysis of randomized trials [0.03%]
低强度体外冲击波治疗勃起功能障碍的疗效：随机试验的更新型meta分析研究
Kaneez Fatima,Zahra Abbas,Anjum Un-Noor et al.
Kaneez Fatima et al.
Background: Low-intensity extracorporeal shockwave therapy (Li-ESWT) is proposed for the treatment of erectile dysfunction (ED)....Plain language summary Low-intensity shockwave therapy (Li-ESWT) involves using gentle shockwaves to treat erectile dysfunction (ED) which is when a man has difficulty getting or maintaining a firm erection for sexual activity In a recent study looking at 12 research projects
Comparative effectiveness of robot-assisted vs. open prostatectomy: a real-life nationwide study [0.03%]
机器人辅助与开放前列腺切除术的疗效比较——全国范围的真实世界研究
Grégoire Robert,Patrick Blin,Franck Bladou et al.
Grégoire Robert et al.
At follow-up, care for urinary incontinence and erectile dysfunction were less frequent with RARP (29.7% vs. 37.3%; p < 0.01 and 52.1% vs. 56.3%; p < 0.01, respectively)....Results were similar with all patients after IPTW adjustment except no difference for erectile dysfunction care.
Observational Study
World journal of urology. 2025 Jun 10;43(1):367. DOI:10.1007/s00345-025-05715-0 2025
Quality over quantity: how to get the best results when using docking for repurposing [0.03%]
以质定量——如何在药物再利用对接中获得最佳效果
Lenin Domínguez-Ramírez,Maricruz Anaya-Ruiz,Paulina Cortés-Hernández
Lenin Domínguez-Ramírez
In this paper, we compared eight free license docking programs to screen a drug library against the human target, phosphodiesterase 5A (PDE5A), to evaluate their ability to find its known ligand, sildenafil, and other ligands that became erectile dysfunction drugs because they inhibit this target.
Comparative Analysis of the Quality of Life Among Men With Premature Ejaculation and Erectile Dysfunction at a Tertiary Care Hospital in Bangladesh [0.03%]
孟加拉国一家三级护理医院早泄和勃起功能障碍男性生活质量的比较分析
Mohammad Shamsul Ahsan,Leuza Mubassara,Md Mahbubul Hasan et al.
Mohammad Shamsul Ahsan et al.
Background: Premature ejaculation (PE) and erectile dysfunction (ED) are among the most prevalent sexual disorders in men, significantly impairing quality of life (QoL).
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