The Role of Genetic Variations in the FAAH rs324420 Polymorphism and its Interaction with CRHR1 rs110402 and CNR1 rs2180619 in Anxiety and- Trauma Related Symptoms After Military Deployment [0.03%]
FAAH基因多态性在(rs324420)和压力原激素受体1(rs110402)以及大麻素受体1 (rs2180619)相关焦虑症及创伤症状的相互作用中所起的作用
Nadia Leen,Antoin de Weijer,Marco Boks et al.
Nadia Leen et al.
Background: During military deployment, stress regulation is vital to protect against the development of anxiety and trauma-related symptoms. Brain endocannabinoids play an important role in stress regulation and previous...
Genetic Contributions to Attachment Stability Over Time: the Roles of CRHR1 Polymorphisms [0.03%]
时间推移中CRHR1基因多态性对依恋稳定性的贡献
Wenping Zhao,Qi Lan,Mingzhu Zhou et al.
Wenping Zhao et al.
Corticotropin-releasing hormone receptor 1 (CRHR1), a hormone receptor essential to the activation of HPA axis and the subsequent release of cortisol, plays critical roles in emotional and behavioral responses relevant to attachment. Howeve...
CRHR1 polymorphism at rs242941, rs242940, and rs72834580: association of symptoms improvement with intranasal corticosteroids in allergic rhinitis Jordanian patients [0.03%]
多态性与变应性鼻炎患者的内舒拿治疗反应关系研究
Malek Zihlif,Osama H Abusara,Walid Al-Qerem et al.
Malek Zihlif et al.
Objectives: Rhinitis is classified into several types with allergic rhinitis (AR) being the most common. AR is among the inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), in which cor...
A Candidate Gene Association Study of FKBP5 and CRHR1 Polymorphisms in Relation to War-Related Posttraumatic Stress Disorder [0.03%]
与战争相关 PTSD 的候选基因关联研究:FKBP5 和 CRHR1 多态性的关系
Nenad Jaksic,Emina Šabić Džananović,Branka Aukst Margetic et al.
Nenad Jaksic et al.
Background: Posttraumatic stress disorder (PTSD) is a highly frequent and disabling psychiatric condition among war-affected populations. The FK506-binding protein 5 (FKBP5) gene and the corticotropin-releasing hormone re...
Influence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach [0.03%]
CRHR1基因多态性和儿童期虐待对心境障碍自杀企图影响的G×E研究
Birgit Ludwig,Klemens Kienesberger,Laura Carlberg et al.
Birgit Ludwig et al.
Background: Previous studies have shown that the hypothalamus-pituitary-adrenal-axis (HPA-axis) is closely involved in the development of affective disorders. Given that early life events are also linked to dysregulation of the same system,...
FKBP5 and CRHR1 polymorphisms moderate the stress-physical health association in a national sample [0.03%]
FKBP5和CRHR1多态性调节全国样本中的压力与身体健康关系
Jared Lessard,E Alison Holman
Jared Lessard
Objective: Stressful life events experienced during childhood and as an adult negatively impact mental and physical health over the life span. This study examined polymorphisms from 2 hypothalamic-pituitary-adrenal axis-r...
Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms [0.03%]
脆性X综合征前突变女性的抑郁和焦虑症状:CRHR1基因多态性调节照顾脆性X综合征子女的影响
Jessica Ezzell Hunter,Mary Leslie,Gloria Novak et al.
Jessica Ezzell Hunter et al.
The fragile X mental retardation gene, FMR1, contains a polymorphic CGG repeat in the 5'-untranslated region of exon 1. Once unstable, this repeat is capable of expansion across generations. Women who carry a premutation allele (55-199 repe...
Genotyping the CRHR1 rs242939 (A>G) polymorphism by a one-step tetra primer-amplification refractory mutation system-polymerase chain reaction [0.03%]
一步四重臂折射性突变聚合酶链式反应对CRHR1基因rs242939(A>G)多态性的基因分型研究
Neeraj Sharma,Shally Awasthi,Subha R Phadke et al.
Neeraj Sharma et al.
Aims: With the rapid advances in molecular techniques, various methods for genotyping single-nucleotide polymorphisms (SNPs) are available. Still, the search for easy, robust, and less costly techniques continues. We wish...
Association between CRHR1 polymorphism and improved lung function in response to inhaled corticosteroid in patients with COPD [0.03%]
CRHR1基因多态性与慢性阻塞性肺疾病患者吸入糖皮质激素改善肺功能之间的关系
Woo J Kim,Seung S Sheen,Tae-Hyung Kim et al.
Woo J Kim et al.
Background and objective: Inhaled corticosteroids are used to treat COPD and asthma. An association between sequence variants in the corticotrophin-releasing hormone receptor 1 (CRHR1) gene and improved lung function in a...
CRHR1 polymorphisms predict bone density in survivors of acute lymphoblastic leukemia [0.03%]
CRHR1基因多态性可预测急性淋巴细胞白血病幸存者的骨密度
Terreia S Jones,Sue C Kaste,Wei Liu et al.
Terreia S Jones et al.
Purpose: Corticosteroids are a critical component of therapy for acute lymphoblastic leukemia (ALL) but are associated with late effects, such as osteoporosis. Risk factors remain poorly defined. Because CRHR1 polymorphis...
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