Transcriptome analysis combined with single-cell analysis identified that APOC1 influences cholesterol transport by macrophages in ccRCC [0.03%]
结合转录组和单细胞分析鉴定APOC1通过巨噬细胞胆固醇运输影响ccRCC发展的作用及机制研究
Fengran Guo,Ziyang Ma,Hu Wang et al.
Fengran Guo et al.
Renal cell carcinoma (RCC) is one of the most prevalent categories of cancer worldwide, accounting for approximately 2% of cancer diagnoses and cancer deaths worldwide. various immunotherapeutic strategies have emerged as key approaches to ...
ZKSCAN5 transcriptional regulation of APOC1 modulates ferroptosis via PI3K/AKT/SREBP2/SLC1A5 axis [0.03%]
ZKSCAN5通过PI3K/AKT/SREBP2/SLC1A5轴转录调节APOC1调控铁死亡
Yongbo Liu,Zihao Qi,Shuo Yang et al.
Yongbo Liu et al.
Background: Prostate cancer is a great substantial health challenge among the cancer type with a high incidence and serving as the main cause of cancer-related deaths in men. Apolipoprotein C1 encodes a member of the apol...
Association of APOC1 levels and nutritional indices with clinicopathological features and prognostic value in patients with DLBCL [0.03%]
APOC1水平及营养指数与DLBCL患者的临床病理特征及其预后价值的相关性分析
Wei Wang,Qiqiang Long
Wei Wang
Objective: This study aims to unravel the relationship between apolipoprotein C1 (APOC1) levels, prognostic nutritional index (PNI), and clinicopathological characteristics in patients with diffuse large B-cell lymphoma (...
Association of APOC1 with cortical atrophy during conversion to Alzheimer's disease [0.03%]
载脂蛋白C1与阿尔茨海默病转化过程中皮质萎缩的关系
Sewook Oh,Sunghun Kim,Jun Pyo Kim et al.
Sewook Oh et al.
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder, with its progression influenced by aberrant gene expression and alterations in the brain network topology. Although APOE has been extensively studied in relation to AD, the...
The roles, signalling pathways and therapeutic implications of Apoc1 in cancer [0.03%]
Apoc1在癌症中的作用、信号通路及治疗意义
Hao-Han Guo,Qiang Guo,Qun-Xian Zhang et al.
Hao-Han Guo et al.
The apolipoprotein C (Apoc) family comprises a group of low-molecular-weight proteins that are essential for modulating lipoprotein metabolism, primarily influencing lipid transport and metabolic pathways. Apoc1, a member of the Apoc family...
Insights and perspectives on the role of APOC1 inhibition in modulating immunotherapy outcomes in HCC: Commentary on Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell [0.03%]
APOC1抑制在调节HCC免疫治疗效果中的作用见解和观点：关于基于单细胞RNA测序抑制APOC1通过铁死亡途径促进M2向M1巨噬细胞转化并增强抗PD1免疫治疗的评论
Jiewen Wei
Jiewen Wei
APOC1 expressed in macrophages promotes the pulmonary metastasis of colorectal cancer via CCL2/CCL5 [0.03%]
巨噬细胞中表达的APOC1通过CCL2/CCL5促进结直肠癌肺转移
Fei Qin,Haosheng Zheng,Jiayan Wu et al.
Fei Qin et al.
Metastasis is the main cause of death in colorectal cancer (CRC), and the lungs are common sites of metastasis. However, there is little effective target to intervene colorectal cancer pulmonary metastasis (CCPM), especially on its unique i...
APOC1, transcriptionally regulated by FOXM1, promotes M2 macrophage polarization and cervical cancer progression [0.03%]
由FOXM1转录调节的APOC1促进M2巨噬极化和宫颈癌进展
Qing Chai,Yan Qi,Xiaoyan Nie et al.
Qing Chai et al.
Background: Cervical cancer (CC) is a common malignant tumor in women. M2 macrophages are associated with tumor growth, metastasis, and immunosuppression. Apolipoprotein C1 (APOC1) has been confirmed as an oncogene in CC....
Integrated analysis of single-cell and bulk RNA sequencing identifies APOC1 as a biomarker and therapeutic target for G0/G1 cell cycle arrest in cholangiocarcinoma [0.03%]
单细胞及大量RNA测序的综合分析确定APOC1为胆管癌G0/G1期细胞周期阻滞的生物标志物和治疗靶点
Qinlei Wang,Zhaowei Sun,Maobing Wang et al.
Qinlei Wang et al.
Cholangiocarcinoma is characterized by its high malignancy, frequent recurrence and insensitivity to conventional radiotherapy and chemotherapy. This resistance may be associated with the presence of cells in the G0/G1 arrest phase within t...
ALYREF-Mediated Regulation of TBL1XR1 and KMT2E Synergistically Upregulates APOC1, Contributing to Oxaliplatin Resistance in Esophageal Cancer [0.03%]
ALYREF通过协同调节TBL1XR1和KMT2E上调APOC1介导的奥沙利铂耐药在食管癌中的作用机制研究
Jie Hu,Qilong Liu,Bi Feng et al.
Jie Hu et al.
Purpose: Esophageal cancer (EC) is a rapidly progressing malignancy characterized by a low survival rate and limited treatment success, largely due to late-stage detection, frequent recurrence, and a high propensity for m...
耗时 0.11986 秒，为您在
48770473
条记录里面共找到 106 篇文章 [XML]