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Bruno Tavares Sedassari,Marcelo Fonseca Celin,Fernanda Mombrini Pigatti Bruno Tavares Sedassari
SMARCB1-deficient sinonasal carcinoma is a rare sinonasal malignancy characterized by loss if INI1 expression on immunohistochemistry due to biallelic loss of SMARCB1 gene. Oral involvement is a an exceedingly unusual event. We present a 59...
Ken Matsumoto,Shiro Akahani Ken Matsumoto
Human papillomavirus-related multiphenotypic sinonasal carcinoma (HMSC) is a rare sinonasal tract tumor. Although HMSC has a favorable prognosis, patients tend to experience local recurrence after the initial therapy; therefore, careful fol...
Daria Rometsch,Frank Simon,Philipp Göttker et al. Daria Rometsch et al.
Introduction: Sinonasal carcinomas (SNC) are rare, aggressive tumours with complex immunological aspects. Still, prognostic markers are missing. The study aimed to investigate the relationship between immune checkpoints -...
Alberto Daniele Arosio,Elisa Coden,Alessia Lambertoni et al. Alberto Daniele Arosio et al.
Objective: Surgery remains a cornerstone in treatment of sinonasal malignancies, but the prognostic role of margin status is controversial. This systematic review and meta-analysis evaluated the prognostic significance of...
Qinyuan Li,Tarek Abi-Saab,Andrey Prilutskiy et al. Qinyuan Li et al.
Background: SMARCB1-deficient and SMARCA4-deficient sinonasal carcinomas are rare, with only a few systematic studies available in the literature. Secondary EWSR1 gene abnormalities have been reported in SMARCB1-deficient...
Matthew E Witek,Matthew C Ward,Richard Bakst et al. Matthew E Witek et al.
Tumors of the paranasal sinus and nasal cavity (PNS/NC) are rare and exhibit diverse histology, anatomic subsite, and malignant potential. Early-stage disease is typically managed with surgery, and locally advanced disease is treated with a...
Avraham E Adelman,Kartik Motwani,Nikita Chapurin Avraham E Adelman
Background: The incidence of human papilloma virus (HPV)-mediated head and neck (H/N) cancers has risen dramatically. While most HPV-associated H/N cancers are oropharyngeal squamous cell carcinoma (OPSCC), sinonasal squa...
Quentin-Alexandre Parys,Matthias De Witte,Esther Hauben et al. Quentin-Alexandre Parys et al.
Background: Sinonasal intestinal-type adenocarcinoma (ITAC) is a rare disease entity. In contrast to most previous studies, this cohort study consists of a substantial number of uniformly treated patients undergoing endos...
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