Refining Assisted Reproductive Technology Strategy in Nonobstructive Azoospermia: Synchrony, Sperm Quality, and Oocyte Availability [0.03%]
非梗阻性无精子症辅助生殖技术策略的优化：同步、精子质量和卵子可用性
Sandro C Esteves
Sandro C Esteves
KIF2C Deletion Causes Meiotic Abnormalities and Nonobstructive Azoospermia in Mice [0.03%]
KIF2C缺失导致小鼠减数分裂异常和非梗阻性无精子症
Hiroaki Kitakaze,Haruhiko Miyata,Yuki Oyama et al.
Hiroaki Kitakaze et al.
Purpose: Kinesin Family Member 2C (KIF2C) is a key regulator of microtubule dynamics and chromosome segregation in mitosis. However, its role in spermatogenesis remains unclear. Recent transcriptomic analyses suggest a po...
Comparison of upper, middle, and lower pole pathologic biopsies of the testes in patients with non-obstructive azoospermia [0.03%]
非阻塞性无精子症患者睾丸上、中、下极病理性活检的比较分析
Onur Dede,Mazhar Utanğaç
Onur Dede
Introduction: Infertility is a widespread global health issue with a multifactorial etiology, affecting a significant proportion of couples. Male factors, either alone or in combination with female factors, play a crucial...
scRNA-seq and scATAC-seq reveal that Sertoli cell mediates spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia [0.03%]
单倍体染色体异常生精障碍的Sertoli细胞介导了不同阶段的细胞间通信：scRNA-seq和scATAC-seq分析结果
Shimin Wang,Hongxian Wang,Bicheng Jin et al.
Shimin Wang et al.
Non-obstructive azoospermia (NOA) belongs to male infertility due to spermatogenesis failure. However, evidence for cell type-specific abnormalities of spermatogenesis disorders in NOA remains lacking. We performed single-cell RNA sequencin...
INTRATESTICULAR AUTOLOGOUS PLATELET RICH PLASMA INJECTION IN COUPLES WITH NON-OBSTRUCTIVE AZOOSPERMIA: A NARRATIVE REVIEW [0.03%]
非梗阻性无精子症夫妇的睾丸内自体富血小板血浆注射：一篇叙事综述
Yigit Cakiroglu,Tansu Gudelci,Bulent Tiras
Yigit Cakiroglu
Azoospermia is the most severe form of male infertility presenting around 1% of the male population and 5%-10% of infertile men. Azoospermia is classified into two categories: obstructive azoospermia (OA) and non-obstructive azoospermia (NO...
Health risks associated with infertility and non-obstructive azoospermia [0.03%]
与不孕和非阻塞性无精子症相关的健康风险
Huyghe Eric,Peter Ka-Fung Chiu
Huyghe Eric
Non-obstructive azoospermia is a common condition associated with significant health risks, including increased mortality, cancer, and chronic diseases such as metabolic and cardiovascular disorders. This review aims to highlight the potent...
Unraveling a subgroup of men with unexplained male infertility - men with normogonadotropic non-obstructive azoospermia [0.03%]
解开一组不明原因男性不育亚群的谜团——正常性激素水平的非阻塞性无精子症患者
Vanessa Schwarzkopf,Joachim Wistuba,Reinhild Sandhowe-Klaverkamp et al.
Vanessa Schwarzkopf et al.
Context: Non-obstructive azoospermia (NOA) constitutes male infertility with complete absence of sperm in the ejaculate. NOA can originate in testicular malfunction or in endocrine dysregulation. Elevated FSH levels are d...
A comparison of the expression patterns and diagnostic capability of the ncRNAs NEAT1 and miR-34a in non-obstructive azoospermia and severe oligospermia [0.03%]
长链非编码RNA与microRNA在无阻塞性无精子症和严重少精症中的表达及诊断价值研究
Aya Salman,Abdullah F Radwan,Olfat G Shaker et al.
Aya Salman et al.
Infertility is a major global health problem, affecting 8-12% of couples worldwide, with male causes contributing to approximately 50% of cases. Notably, around 15% of infertile men are azoospermic. Consequently, there is a critical necessi...
Comparative Study
Human genomics. 2025 Mar 31;19(1):35. DOI:10.1186/s40246-025-00742-9 2025
Response to: Critical appraisal of "pregnancy outcomes in patients with non-obstructive azoospermia undergoing micro-TESE: comparison of fresh vs. frozen-thawed testicular sperm" [0.03%]
对《显微镜下取精术获取新鲜或冷冻精子在非阻塞性无精子症患者妊娠结局中的应用对比》一文的评论回应
Lala Suleymanova,Hale Bayram,Yaprak Dönmez Çakıl et al.
Lala Suleymanova et al.
The power of the map: testicular mapping to guide surgical sperm retrieval in patients with non-obstructive azoospermia [0.03%]
地图的力量：睾丸绘图引导非梗阻性无精子症患者的手术取精
Arash Amighi,Alvaro Santamaria,Theodore Crisostomo-Wynne et al.
Arash Amighi et al.
Background: For male infertility patients with suspected non-obstructive azoospermia, fine needle aspiration mapping (FNAM) of the testis identifies and locates sperm and guides surgical sperm retrieval (SSR), offering an...
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