Nociceptin-opioid-related nociceptin receptor 1 signaling partly mediates glucoprivic suppression of luteinizing hormone pulses in female rats: arcuate Kiss1 neurons as a possible target for nociceptin [0.03%]
阿片受体相关的伤害性肽-1信号部分介导了糖原剥夺对雌鼠黄体生成素脉冲的抑制作用：伤害性肽可能作用于下丘脑弓状核Kiss1神经元
Marina Takizawa,Koki Yamada,Mayuko Nagae et al.
Marina Takizawa et al.
Introduction: During malnutrition, mammalian reproductive functions are suppressed by inhibition of the pulsatile release of gonadotropin-releasing hormone (GnRH)/gonadotropins. This study aimed to investigate whether noc...
Myofibroblast-like Cells and Junctional Complex Development Play a Role in Mouse Pubic Symphysis Remodeling During Pregnancy and Postpartum [0.03%]
妊娠和产后雌鼠会阴部骨骼的重塑与类似肌成纤维细胞的作用及连接复合体的发展有关
Viviane Souza Rosa,Bianca Gazieri Castelucci,Monica Moreira et al.
Viviane Souza Rosa et al.
During mouse pregnancy, the pubic symphysis (PS) undergoes a gradual transitioning into an interpubic ligament (IpL) for a successful delivery. After birth, this IpL is rapidly remodeled, returning to the non-pregnant morphology. The PS fib...
RFRP neurons are required for acute stress-induced suppression of the estrogen-stimulated LH surge in female mice [0.03%]
催乳素释放激素神经元通过急性应激抑制雌鼠促性腺激素释放激素诱发的黄体生成素高峰的作用机制研究
Maggie C Evans,Shaun M Stowe,India L Sawyer et al.
Maggie C Evans et al.
The association between perceived stress and reproductive dysfunction is known, yet the underlying mechanisms remain incompletely determined. We previously demonstrated that RF-amide related peptide 3 (RFRP-3)-expressing neurons, putative i...
Divergent effects of win-paired cues on learning from timeout penalties in female and male rats [0.03%]
正性条件刺激物对雄性和雌性大鼠限时处罚学习的影响不同
Claire A Hales,April Hwang,Brett A Hathaway et al.
Claire A Hales et al.
In both males and females, linking rewards with salient audiovisual cues in simulated gambling games increases risky choice in humans and rats. However, the prevalence and severity of gambling problems differs in men and women. In previous ...
Apelin-13 elicits lordosis behavior in female rats through the oxytocin/prostaglandin E2/GnRH signaling system [0.03%]
阿皮林通过催产素/前列腺素E2/GnRH信号系统激发雌鼠交配行为
Raymundo Domínguez-Ordóñez,Marcos García-Juárez,José Luis Encarnación-Sánchez et al.
Raymundo Domínguez-Ordóñez et al.
The present study investigated the role of the oxytocin (OT)/prostaglandin E2 (PGE2)/gonadotropin-releasing hormone (GnRH) and the progesterone receptor (PR) pathways in facilitating lordosis behavior induced by intrahypothalamic administra...
Androgens alleviate the depression-like phenotype in female mice by inhibiting AVPR1a in the hippocampal brain region [0.03%]
雄激素通过抑制海马脑区的AVPR1a来缓解雌鼠的抑郁表型
Shimin Ren,Xian Wang,Xueying Huang et al.
Shimin Ren et al.
Background: The prevalence of depression in women is approximately twice that in men. Differences in androgens levels between men and women, due to gonadal differences, may be associated with the development of depression...
Combined Effects of Mechanical Loading and Piezo1 Chemical Activation on 22-Months-Old Female Mouse Bone Adaptation [0.03%]
力学刺激与Piezo1化学激活对22月龄雌鼠骨适应的联合效应
Quentin A Meslier,Robert Oehrlein,Sandra J Shefelbine
Quentin A Meslier
With age, bones mechanosensitivity is reduced, which limits their ability to adapt to loading. The exact mechanism leading to this loss of mechanosensitvity is still unclear, making developing effective treatment challenging. Current treatm...
Amir Farshad Shadman
Amir Farshad Shadman
The light regulation within laboratory environments is critical for ensuring the wellbeing and accurate study of nocturnal animals like Syrian hamsters. This study evaluated the instinctual light color preferences of 18 adult female Syrian ...
Effects of unpredictable chronic mild stress of female rats before pregnancy on morphine-induced antinociceptive tolerance in offspring [0.03%]
孕前慢性轻度不可预测性应激对雌鼠子代吗啡耐受的影响
Nastaran Roshd Rashidi,Nahid Khodayari,Mehdi Sadegh et al.
Nastaran Roshd Rashidi et al.
Background: Prenatal chronic stress can impact pain sensitivity and analgesic responses in offspring. This study investigates oxidative stress markers in the ovaries of female rats that experienced unpredictable chronic m...
Chronic Intermittent Hypoxia and Ovariectomy Exert Independent and Region-specific Effects on ΔFosB Expression and Increase Blood Pressure in Female Rats [0.03%]
慢性间歇性低氧和卵巢切除独立并区域特异性地影响雌鼠ΔFosB表达及血压升高效应
Cephas B Appiah,Joel T Little,George E Farmer et al.
Cephas B Appiah et al.
Chronic intermittent hypoxia (CIH), a preclinical model of hypoxemia associated with sleep apnea, causes hypertension associated with increased sympathetic activity linked to arterial chemoreflex and renin-angiotensin system activation. In ...
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