Hang Du,Dongjin Wu,Tianyu Zhang et al. Hang Du et al.

Osteosarcoma (OS) is the most prevalent primary malignant bone tumor affecting children and adolescents. Despite ongoing research efforts, the 5-year survival rate has remained stagnant for many years, highlighting the critical need for nov...

Fangfang Li,Lu Chen,Sha Shi et al. Fangfang Li et al.

Perfluorobutanoic acid (PFBA) is an emerging contaminant that was demonstrated to exhibit estrogen effects via action on classic estrogen receptors (ERs) in a low-activity manner. The purpose of the present study is to reveal the estrogen d...

Rajesh Kumar Pathak,Jun-Mo Kim Rajesh Kumar Pathak

The use of Bisphenol A (BPA) and its analogs in industries, as well as the products made from them, is becoming a significant concern for human health. Scientific studies have revealed that BPA functions as an endocrine disruptor. While som...

Qiaochu Wang,Nanxi Huang,John B Psaltis et al. Qiaochu Wang et al.

Objective: Estrogen-related receptor γ (ERRγ) is a metabolic regulator with no identified physiological ligands. This study investigates whether calcium is an ERRγ ligand that mediates the effects of glucagon and wheth...

Nanthini Sadasivam,Woo-Ram Park,Byungyoon Choi et al. Nanthini Sadasivam et al.

Estrogen-related receptor gamma (ERRγ) is a member of the ERR orphan nuclear receptor family which possesses three subtypes, α, β, and γ. ERRγ is reportedly predominantly expressed in metabolically active tissues and cells, which promo...

Rajesh Kumar Pathak,Jun-Mo Kim Rajesh Kumar Pathak

Bisphenol A (BPA) is a very important chemical from the commercial perspective. Many useful products are made from it, so its production is increasing day by day. It is widely known that Bisphenol A (BPA) and its analogs are present in the ...

Yoon Seok Jung,Kamalakannan Radhakrishnan,Hyo-Jin Kim et al. Yoon Seok Jung et al.

Macrophage stimulating protein (MSP) is a multifunctional serum protein produced in the liver, belonging to the plasminogen-related kringle protein family. It exerts diverse biological functions by activating a transmembrane receptor protei...

Danesh H Sopariwala,Andrea S Rios,Addison Saley et al. Danesh H Sopariwala et al.

Background Peripheral arterial disease and critical limb ischemia are cardiovascular complications associated with vascular insufficiency, oxidative metabolic dysfunction, and myopathy in the limbs. Estrogen-related receptor gamma (ERRγ) h...

Yiwen Fan,Hyo-Jin Kim,Yoon Seok Jung et al. Yiwen Fan et al.

Fibroblast growth factor 23 (FGF23) is a glycoprotein that belongs to the FGF19 subfamily and participates in phosphate and vitamin D homeostasis. Chenodeoxycholic acid (CDCA), one of the primary bile acids, is reported to induce the secret...

Yong Zheng,Yongli Du,Haibin Zhang et al. Yong Zheng et al.

Estrogen-related receptor gamma (ERRγ), one of three members of the ERR family, is an inducible transcription factor. ERRγ has dual functions in different tissues. The decreased expression of ERRγ in the brain, stomach, prostate, and fat...