An AUDacious Proposal: How to Improve Gastroenterology Fellow Training for Alcohol Use Disorder and Alcohol-Associated Liver Disease [0.03%]
大胆的建议：如何改进胃肠病学住院医师培训以提高酒精使用障碍和酒精相关性肝病的治疗水平
Ysabel C Ilagan-Ying
Ysabel C Ilagan-Ying
Alcohol use disorder (AUD), an increasingly prevalent and treatable cause for alcohol-associated liver disease (ALD), is the most common reason for liver transplantation and liver-related deaths in the United States. Despite overwhelming ev...
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway [0.03%]
乳酸菌通过KEAP1-NRF2途径增强N-乙酰谷氨酸水平和抑制铁死亡来缓解酒精相关性肝病
Hejiao Zhang,Qiang Hu,Yong Zhang et al.
Hejiao Zhang et al.
Alcohol-associated liver disease (ALD) is a prevalent global health issue primarily caused by excessive alcohol consumption. Recent studies have highlighted the gut-liver axis's protective role against ALD, mainly through gut microbiota. Ho...
Unravelling the Complex Role of Glycine-Conjugated Bile Acids and Gut-Liver Axis in Progressive Alcohol-Related Liver Disease [0.03%]
解开甘氨酸 conjugated 胆酸和肠肝轴在进行性酒精相关性肝病中的复杂作用
Yunyi Yang,Yanming He,Hongjie Yang
Yunyi Yang
Chun-Wei Pan,Yazan Abboud,Amit Chitnis et al.
Chun-Wei Pan et al.
Importance: Alcohol-associated liver disease (ALD) is a major public health concern, accounting for one-quarter of cirrhosis-related deaths and becoming the leading indication for liver transplantation in the US, with con...
GLP-1 receptor agonists in alcohol use disorder and alcohol-associated liver disease [0.03%]
葡萄糖依赖性促胰岛素多肽受体激动剂在酒精使用障碍和酒精相关肝病中的应用
Ashwani K Singal,Lorenzo Leggio
Ashwani K Singal
Dissecting metabolic dysfunction- and alcohol-associated liver disease (MetALD) using proteomic and metabolomic profiles [0.03%]
利用蛋白质组学和代谢组学谱型分析代谢功能紊乱和酒精相关性肝病(MetALD)
Jun Liu,Sihao Xiao,Sile Hu et al.
Jun Liu et al.
Background: & Aim, Metabolic dysfunction associated and alcohol associated liver disease (MetALD) is a poorly understood condition that bridges cardiometabolic and alcohol-related pathological characteristics. We aim to d...
Site-specific alterations of bone matrix mineralization, micro-hardness and density of mineralized osteocyte lacunae in men with alcohol-associated liver disease: implications for vertebral fracture predilection [0.03%]
酒精相关肝病男性患者骨基质矿化、微硬度和骨硬化细胞腔隙密度的位点特异性改变：对椎体骨折易感性的意义
Jelena Jadzic,Christine Plumeyer,Danica Djukic et al.
Jelena Jadzic et al.
Low bone quality has been reported as a source of bone fragility in individuals with alcohol-associated liver disease (AALD). Alterations of the bone matrix, including the spatial bone mineral density distribution and osteocyte lacunar netw...
Effect of aging on the development and progression of alcohol-associated liver disease [0.03%]
衰老对酒精性肝病发生发展的影响研究进展
Ramesh Bellamkonda,Sundararajan Mahalingam,Ojeshvi Ethiraj et al.
Ramesh Bellamkonda et al.
Background: There is a robust link between chronic alcohol intake and the development of alcohol-associated liver disease (ALD). Over 90% of excessive alcohol drinkers develop hepatic steatosis that can progress to an adv...
Richard Parker,Juan P Arab,Jeffrey V Lazarus et al.
Richard Parker et al.
Alcohol-related liver disease (ALD) is a major cause of morbidity and premature mortality around the world, with a substantial cost to individuals and to health-care systems. The incidence of ALD is closely associated with alcohol intake, a...
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