Modulating lipid metabolism for enhancement of coenzyme Q10 production in Rhodobacter sphaeroides [0.03%]
调节类脂代谢以提高Rhodobacter sphaeroides中辅酶Q10的产量
Xinru Bao,Jie Zhong,Zikang Huang et al.
Xinru Bao et al.
Coenzyme Q10 (CoQ10), a lipid-soluble isoprenylated benzoquinone essential for electron transfer, is synthesized in the inner mitochondrial membrane of eukaryotes and plasma membrane of prokaryotes like Rhodobacter sphaeroides. Despite its ...
Effects of coenzyme Q10 administration on blood pressure and heart rate in adults: A systematic review and meta-analysis of randomized controlled trials [0.03%]
辅酶Q10对成人血压和心率影响的系统评价和meta分析：随机对照试验
Mehdi Karimi,Samira Pirzad,Farnaz Hooshmand et al.
Mehdi Karimi et al.
Background and objective: Coenzyme Q10 is a naturally occurring antioxidant that has been suggested to improve cardiovascular health. Studies examining the effects of Q10 on blood pressure (BP) and heart rate (HR) have fo...
Antineovascular Effects of Coenzyme Q10 and Vitamin E Combination in Corneal Neovascularization: A Pilot Study [0.03%]
辅酶Q10和维生素E联合应用对角膜新生血管的抗血管生成作用：一项初步研究
Armağan Özgür,Mehmet Cüneyt Özmen,Duygu Yalınbaş Yeter et al.
Armağan Özgür et al.
Purpose: To evaluate and compare the effects of subconjunctival injection of coenzyme Q10 (CoQ10) and vitamin E (Vit E) ophthalmic solution (Coqun®) with subconjunctival bevacizumab in a suture-induced corneal neovascularization (CoNV) rab...
Enhanced solubility and bioavailability of coenzyme Q10 via co-amorphous system using stevioside [0.03%]
利用 Stevioside 构建 Co-Q10 共无定形系统提升其溶解度和生物利用度
Yingting Luo,Yuxin Li,Xuening Song et al.
Yingting Luo et al.
Coenzyme Q10 (CoQ10) plays a vital role in aerobic respiration and cardiovascular diseases; however, its application is limited owing to poor water solubility. In this study, equimolar CoQ10 and stevioside (STE) formed a co-amorphous (CM) s...
Blended Phenotypes of Sexual Development Disorder and Coenzyme Q10 Deficiency, Together with a Sibling with Homozygous Variants in the AHI1 Gene [0.03%]
AHI1基因纯合变异的兄弟姐妹合并性发育障碍和辅酶Q10缺乏的混合表型
Rumeysa Atasay,Leyla Nur Yilmaz,Ayten Gulec et al.
Rumeysa Atasay et al.
Introduction: In consanguineous marriages, different homozygous variants in a single gene may occur in the same family. This may lead to blended phenotypes. This study presents a family in which different rare mechanisms ...
Case Reports
Molecular syndromology. 2025 May;16(3):271-277. DOI:10.1159/000541717 2025
Combined treatment with IGF1, CoQ10 and melatonin improves the quality of bovine oocytes and heat-shocked blastocysts† [0.03%]
IGF1，CoQ10和褪黑激素联合治疗可改善牛卵母细胞和热应激囊胚的质量
Hang Zhang,Baigao Yang,Peipei Zhang et al.
Hang Zhang et al.
Heat stress significantly impairs cattle fertility, particularly affecting oocytes and developing blastocysts. Developing strategies to improve embryonic development under heat stress is crucial for advancing the cattle breeding industry. T...
Success of Coenzyme Q10 in Treating Steroid-Resistant Nephrotic Syndrome in Jordan: A Case Series [0.03%]
辅酶Q10治疗约旦肾病综合征患者糖皮质激素抵抗型病例系列研究的初步成功报告
Mahdi Q Frehat Sr,Aghadir Alhadidi,Abdallah Almhairat et al.
Mahdi Q Frehat Sr et al.
Focal segmental glomerulosclerosis (FSGS) is one of the leading causes of primary end-stage kidney disease in the pediatric age group. It is commonly associated with steroid-resistant nephrotic syndrome (SRNS), which ultimately leads to imp...
Case Reports
Cureus. 2025 Apr 30;17(4):e83231. DOI:10.7759/cureus.83231 2025
Protective role of coenzyme Q10 against trihexyphenidyl-induced pulmonary toxicity in Wistar rats [0.03%]
辅酶Q10对减少Wistar大鼠Trihexyphenidyl致肺毒性的保护作用研究
Joseph Gbenga Omole,Lydia Oluwatoyin Ajayi,Itunuoluwa Rachael Ajewole et al.
Joseph Gbenga Omole et al.
Background: Trihexyphenidyl (THP), an anticholinergic drug used to manage Parkinson's disease and dystonia, has been associated with oxidative stress and metabolic disturbances, particularly affecting pulmonary function. ...
Biochemical, histological, and immunohistochemical study on the therapeutic effects and mechanism of coenzyme Q10 in type 2 diabetes mellitus [0.03%]
辅酶Q10治疗2型糖尿病疗效及机制的生化、组织病理和免疫组化研究
Manal Ismaeil Khalil,Ali Louei Monfared,Hussein Bashar Mahmood
Manal Ismaeil Khalil
Background and purpose: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by β-cell dysfunction, insulin resistance, and elevated blood sugar levels. Several studies have explored the therapeutic pote...
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