Amino acid residues critical to cAMP signaling by V2a-type vasopressin/vasotocin receptor: an evolutionary perspective [0.03%]
从进化角度探究V2a型血管加压素/血管紧张素受体cAMP信号转导的关键氨基酸残基
Yoko Yamaguchi
Yoko Yamaguchi
Vasopressin (VP) and its non-mammalian homolog vasotocin (VT) are secreted from the posterior pituitary to control various physiological phenomena via G protein-coupled receptors. The six known subtypes of VP/VT receptor family (V1a/bR and ...
Non-peptidic natural products that target and modulate oxytocin and arginine vasopressin receptors: Opportunities and challenges [0.03%]
非肽类天然产物作用于和调节催产素和血管加压素受体的机会与挑战
Dane Tregeagle,Catherine Doherty,Timothy Callis et al.
Dane Tregeagle et al.
The ability to target the oxytocin and vasopressin receptors is of high therapeutic value due to their clinical relevance in wide range of neuropsychiatric conditions spanning from anxiety to schizophrenia. Despite the massive therapeutic p...
Correction: Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy [0.03%]
关于血管加压素受体type-2作为肾细胞癌治疗靶点的更正研究论文
Sonali Sinha,Nidhi Dwivedi,Shixin Tao et al.
Sonali Sinha et al.
Published Erratum
Oncogene. 2025 Jan 27. DOI:10.1038/s41388-025-03279-2 2025
Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice [0.03%]
血管加压素受体缺陷小鼠肠道丁酸介导的肠激素分泌和脂质代谢紊乱
Kazuki Harada,Eiji Wada,Yuri Osuga et al.
Kazuki Harada et al.
Objectives: Arginine vasopressin (AVP), known as an antidiuretic hormone, is also crucial in metabolic homeostasis. Although AVP receptor-deficient mice exhibit various abnormalities in glucose and lipid metabolism, the m...
Correlation analysis of AVPR1a and AVPR2 with abnormal water and sodium and potassium metabolism in rats [0.03%]
AVPR1a和AVPR2与大鼠水钠钾代谢紊乱的相关性分析研究
Kun Sun,Yingzhu Qiu,Yao Sun
Kun Sun
In clinical practice, an increasing number of patients exhibit concurrent cardiac and renal dysfunction, known as "cardiorenal syndrome," where each condition exacerbates the other, resulting in poorer patient prognosis. Fluid and sodium re...
Parenthood and gene expression of oxytocin receptors and vasopressin receptors in sensory cortices of the male California mouse (Peromyscus californicus) [0.03%]
父性行为与加州鼠雄性的感觉皮层催产素受体和血管加压素受体基因表达的关系研究
Kerianne M Wilson,Tjien Dwyer,Alison V Ramirez et al.
Kerianne M Wilson et al.
The onset of parental care is associated with shifts in parents' perception of sensory stimuli from infants, mediated by neural plasticity in sensory systems. In new mothers, changes in auditory and olfactory processing have been linked to ...
Implication of vasopressin receptor genes (AVPR1A and AVPR1B) in the susceptibility to polycystic ovary syndrome [0.03%]
血管加压素受体基因（AVPR1A和AVPR1B）在多囊卵巢综合征易感性中的作用
Pruthvi Goparaju,Claudia Gragnoli
Pruthvi Goparaju
Background: Polycystic ovary syndrome (PCOS) is a complex heterogenous disorder manifesting with various reproductive, endocrine, and metabolic derangements such as insulin resistance and hyperglycemia. The arginine vasop...
Activation of arginine vasopressin receptor 1a reduces inhibitory synaptic currents at reciprocal synapses in the mouse accessory olfactory bulb [0.03%]
血管加压素受体1a的激活减少小鼠副嗅球互反突触的抑制性突触电流
Mutsuo Taniguchi,Yoshihiro Murata,Masahiro Yamaguchi et al.
Mutsuo Taniguchi et al.
Central arginine vasopressin (AVP) facilitates social recognition and modulates many complex social behaviors in mammals that, in many cases, recognize each other based on olfactory and/or pheromonal signals. AVP neurons are present in the ...
Dopamine, norepinephrine, and vasopressin accelerate particle transport velocity in murine tracheal epithelium via substance-specific receptor pathways: dependency on intra- and extracellular Ca2+ sources [0.03%]
多巴胺、去甲肾上腺素和血管加压素通过特定物质的受体通路加速小鼠气管上皮颗粒运输速度：依赖于细胞内和细胞外钙离子来源
Götz Schmidt,Isabelle Greif,Sabrina Müller et al.
Götz Schmidt et al.
Background: The unique ability of the respiratory tract to protect the integrity of the airways by removing potentially harmful substances is defined as mucociliary clearance. This complex physiological mechanism protects...
The Vasopressin Receptor Antagonist Tolvaptan Counteracts Tumor Growth in a Murine Xenograft Model of Small Cell Lung Cancer [0.03%]
血管加压素受体拮抗剂托伐普坦在小细胞肺癌异种移植模型中具有抑制肿瘤生长的作用
Laura Naldi,Benedetta Fibbi,Simone Polvani et al.
Laura Naldi et al.
We have previously demonstrated that the vasopressin type 2 receptor (AVPR2) antagonist tolvaptan reduces cell proliferation and invasion and triggers apoptosis in different human cancer cell lines. To study this effect in vivo, a xenograft...
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