Hypoxanthine activates PI3K/AKT pathway and lipid metabolism, hallmarks in breast cancer metastasis [0.03%]
次黄嘌呤通过激活磷脂酰肌醇三磷酸激酶/蛋白激酶B信号途径和脂质代谢，促进乳腺癌的转移
Sarra B Shakartalla,Amal Bouzid,Alaa M Altaie et al.
Sarra B Shakartalla et al.
Metastasis is the primary cause of death in women with breast cancer, which ranks among the most prevalent malignant diseases. Recently, we identified the significant metastatic role of hypoxanthine (HYP) in cancer cells. HYP is a naturally...
Identification of lipid metabolism-related marker genes in colorectal cancer [0.03%]
结直肠癌中与脂质代谢相关的标记基因识别
Bo Gao,Jitao Hu,Hao Wu et al.
Bo Gao et al.
Objective: To identify lipid metabolism associated biomarkers in colorectal cancer (CRC). Methods: To refine our list of candidate gene...
The analysis of distinctive lipid metabolism characteristics in dry-cured beef during processing [0.03%]
干腌肉制品加工过程中脂质代谢特征分析
Huihui Fu,Jiaxin Jin,Sheng Xiao et al.
Huihui Fu et al.
Dry-cured beef (DB), CG (control group), FG (fermented group), RG (ripened group) stages were selected to analyse the key lipid metabolites using the lipid metabolism approach based on UPLC-MS/MS. We identified 301 metabolites from 13 subcl...
Dysregulated lipid metabolism in late preterm low birth weight neonates: A case-control study on maternal lipid levels and early metabolic programming implications [0.03%]
极低体重晚产新生儿脂质代谢紊乱：一项关于母亲脂质水平和早期代谢程序影响的病例对照研究
Jing Liu,Lijuan Tang,Qi Sun et al.
Jing Liu et al.
Objectives: While low birth weight (LBW) is a recognized risk factor for adult metabolic syndrome, the unique lipid metabolic phenotype of late preterm low birth weight (LPTB-LBW) neonates-who experience dual exposures to...
Impact of concurrent aerobic and resistance training on body composition, lipid metabolism and physical function in patients with type 2 diabetes and overweight/obesity: a systematic review and meta-analysis [0.03%]
有氧运动和抗阻训练对2型糖尿病合并超重肥胖患者的体成分、脂代谢及身体功能影响的系统评价和Meta分析
Sameer Badri Al-Mhanna,Abdullah F Alghannam,Nouf H Alkhamees et al.
Sameer Badri Al-Mhanna et al.
Background: The potential advantages of concurrent aerobic and resistance training (CART) for enhancing cardiometabolic health-related outcomes appear to surpass the outcomes of engaging in aerobic or resistance training ...
Meta-Analysis
PeerJ. 2025 Jun 11:13:e19537. DOI:10.7717/peerj.19537 2025
Enhanced resistance to Listeria infection in mice surviving sepsis: the role of lipid metabolism and myeloid cell reprogramming [0.03%]
Surviving脓毒症小鼠感染李斯特菌的抗性增强：脂质代谢和髓系细胞重编程的作用
Haruki Watanabe,Tengfei Song,Jaewoo Choi et al.
Haruki Watanabe et al.
Introduction: Immune resilience is the capacity of the immune system to recover from sepsis-induced organ injury and reestablish host defense. While sepsis survivors are often viewed as immunocompromised, recent studies s...
Non-esterified fatty acids disrupt hepatic lipid metabolism and mitochondrial function via TLR4/MyD88/IRAK2 signaling in bovine hepatocytes [0.03%]
非酯化脂肪酸通过TLR4/MyD88/IRAK2信号干扰牛肝细胞的肝脏脂质代谢和线粒体功能
Yongqiang Wen,Yazhou Wang,Juan J Loor et al.
Yongqiang Wen et al.
Excessive non-esterified fatty acids (NEFA) in the blood often lead to ketosis and fatty liver in peripartal cows. The integrity of mitochondrial structure and function plays a key role in the development of lipid metabolism imbalance and i...
Colonic xanthomas in an adult with skeletal anomalies and dyslipidemia: Colonoscopic findings of NSDHL-related CHILD syndrome due to NSDHL haploinsufficiency [0.03%]
成人骨骼畸形和脂质代谢异常结肠黄色瘤的结肠镜检查发现NSDHL功能缺失导致CHILD综合征
Bukola A Olarewaju,Judy B Tejon,Misha B Asif et al.
Bukola A Olarewaju et al.
Integrated metabolomics and network pharmacology reveal the PI3K/Akt-mediated therapeutic mechanism of Abrus cantoniensis in lipid metabolism disorders [0.03%]
整合代谢组学和网络药理学揭示了 Cantoni 苦豆子通过PI3K/AKT介导的治疗机制改善脂质代谢紊乱
Xue Wang,Mingjuan Huang,Yixiang Lu et al.
Xue Wang et al.
Background: Abrus cantoniensis (AC), a hepatoprotective herb, shows therapeutic potential for lipid metabolism disorders (LMDs), yet its mechanisms remain unclear. ...
Comprehensive lipid metabolites-pyroptosis profiling uncovers the therapeutic efficacy of Mailuo Shutong pill against Thromboangiitis obliterans [0.03%]
血脂代谢物-焦亡谱型联合分析探讨脉络舒通丸治疗血栓闭塞性脉管炎的疗效
Chenhan He,Peipei Zhou,Zhibo Zhang et al.
Chenhan He et al.
Ethnopharmacological relevance: Thromboangiitis obliterans (TAO) is a necrotic lesion with complex inflammatory changes in the vessel wall. Mailuo Shutong pill (MLSTP), a traditional Chinese medicine formula (TCM) clinica...
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