A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease [0.03%]
负责介导celiac疾病中组织转谷氨酰胺酶2依赖性免疫反应的树突细胞群
Fu-Chen Yang,Harrison A Besser,Hye Rin Chun et al.
Fu-Chen Yang et al.
In celiac disease (CeD), a gluten-dependent autoimmune disorder, transglutaminase 2 (TG2) deamidates selected glutamine residues in gluten peptides, while HLA-DQ2 presents deamidated antigens to inflammatory T cells. The cellular sources of...
Interactions among secretory immunoglobulin A, CD71, and transglutaminase-2 affect permeability of intestinal epithelial cells to gliadin peptides [0.03%]
分泌型免疫球蛋白A、转谷氨酰胺酶-2和CD71的相互作用影响胶质纤维酸性蛋白肽透过肠上皮细胞的通透性
Corinne Lebreton,Sandrine Ménard,Juliette Abed et al.
Corinne Lebreton et al.
Background & aims: The transferrin receptor (CD71) is up-regulated in duodenal biopsy samples from patients with active celiac disease and promotes retrotransport of secretory immunoglobulin A (SIgA)-gliadin complexes. We...
Expression of the integrin coreceptor transglutaminase-2 in the RPE in vivo and in culture [0.03%]
透析性玻璃膜剥脱症视网膜色素上皮中的整合素辅助受体δ钙调神经磷酸酶β的影响及其机制研究
Linda Ruggiero,Silvia C Finnemann
Linda Ruggiero