A multicenter prospective clinical cohort study of pulmonary cryptococcosis in adult non-HIV-infected patients in a southeastern province of China [0.03%]
中国东南部多中心成人非艾滋病感染者肺隐球病临床队列研究
Meiyan Chen,Shuyang Chen,Meng Wang et al.
Meiyan Chen et al.
Background: This study investigates the clinical presentations, diagnostic approaches, and treatment outcomes of pulmonary cryptococcosis (PC) in non-HIV patients in Fujian Province, and explores the correlation between i...
Multicenter Study
Respiratory research. 2025 Jun 13;26(1):216. DOI:10.1186/s12931-025-03283-w 2025
Pulmonary cryptococcosis in immunocompetent children presenting with chest pain: Three case reports [0.03%]
胸痛免疫健全儿童肺隐球菌病的病例报告一篇文献回顾及三例报道
Xiao-Nan Li,Jie-Hua Chen,Zhi-Wei Lu
Xiao-Nan Li
Background: Cryptococcus is a systemic opportunistic pathogenic fungus that can cause infections in both immunocompromised and immunocompetent hosts, with diverse clinical manifestations, ranging from asymptomatic pulmona...
Diagnostic performance of an in-house real-time polymerase chain reaction (PCR) assay and antigen detection from respiratory samples for the diagnosis of pulmonary cryptococcosis [0.03%]
一套针对肺隐球病诊断的实时聚合酶链式反应和抗原检测试验的性能评估
Karthick Kumar,Hansraj Choudhary,Haseen Ahmad et al.
Karthick Kumar et al.
Introduction: The currently available diagnostic tests lack sensitivity to diagnose pulmonary cryptococcosis. In the current study, we developed and standardized an in-house real-time PCR assay and evaluated the antigen d...
Lateral flow assay as radiological prognosis factor of pulmonary cryptococcosis: a single center retrospective study in China [0.03%]
中国单中心回顾性研究：侧向流检测作为肺隐球病的放射学预后因素
Jiejun Shi,Jianhua Chen,Qianjiang Ding et al.
Jiejun Shi et al.
Background: Lateral flow assay (LFA) has demonstrated high sensitivity and specificity for diagnosing cryptococcosis. However, its role in predicting therapeutic efficacy for pulmonary cryptococcosis (PC) remains underexp...
Pulmonary cryptococcosis associated with Cryptococcus neoformans in an immunocompetent child [0.03%]
一名免疫功能正常的儿童出现新型隐球菌引起的肺隐球病
Jiying Xiao,Jie Chen,Junsong Chen et al.
Jiying Xiao et al.
We report a pediatric case of pulmonary cryptococcosis caused by Cryptococcus neoformans in an immunocompetent child. Although the patient presented with mild clinical symptoms, pulmonary imaging revealed severe abnormalities. The diagnosis...
Dose Optimization of Fluconazole After Initial Treatment Failure in Pulmonary Cryptococcosis in an Obese Patient with Type 2 Diabetes and Cirrhosis: A Case Report [0.03%]
用于治疗二型糖尿病和肝硬化且初始治疗失败的肥胖肺隐球病患者的氟康唑剂量优化：病例报告
Yang Yang,Jin Shang,Shuyun Xu et al.
Yang Yang et al.
Background: Pulmonary cryptococcosis is a fungal infection of the lungs, particularly challenging to treat in patients with multiple comorbidities such as obesity, type 2 diabetes, and cirrhosis. Fluconazole is a first-li...
Clinical characteristics of pulmonary cryptococcosis patients with different immune statuses: A 10-year multicenter retrospective study in China [0.03%]
中国不同免疫状态肺隐球病患者临床特征分析——一项多中心回顾性研究（2009-2018年）
Hansheng Wang,Wenya Han,Chengqing Yang et al.
Hansheng Wang et al.
Background and objective: We aimed to evaluate clinical characteristics and therapeutic efficacy of pulmonary cryptococcosis (PC) in patients with different immune status in a large multicenter population to support appro...
Multicenter Study
Respiratory medicine. 2024 Dec:235:107866. DOI:10.1016/j.rmed.2024.107866 2024
A rare case of disseminated pulmonary cryptococcosis in an immunocompetent patient [0.03%]
免疫功能正常的患者的播散性肺隐球菌病一例
Hafisatu Gbadamosi,Jane Sandra Afriyie-Mensah,Emmanuel Nyamekye Ansah et al.
Hafisatu Gbadamosi et al.
Pulmonary cryptococcosis is an uncommon invasive fungal infection of the lungs seen in immunocompromised individuals but increasingly reported among the immunocompetent. We report a rare case of pulmonary cryptococcosis in an immunocompeten...
LincR-PPP2R5C deficiency enhancing the fungicidal activity of neutrophils in pulmonary cryptococcosis is linked to the upregulation of IL-4 [0.03%]
肺隐球菌病中LincR-PPP2R5C缺乏通过上调IL-4增强中性粒细胞的杀菌活性
Chen Yang,Ying Gong,Shan Liu et al.
Chen Yang et al.
Pulmonary cryptococcosis is a common complication in immunocompromised patients. In a mouse model of pulmonary cryptococcosis, Cryptococcus neoformans induces a type 2 immune response that is detrimental to host protection. Long non-coding ...
The relationship between lung CT features and serum cryptococcal antigen titers in localized pulmonary cryptococcosis patients [0.03%]
局部肺隐球病患者胸部CT表现与隐球菌血清学滴度的相关性研究
Chunmei Dai,Dongyu Bai,Chunbei Lin et al.
Chunmei Dai et al.
Background: To explore the associations of computed tomography (CT) image features with the serum cryptococcal antigen (CrAg) titers measured by the lateral flow assay (LFA) in localized pulmonary cryptococcosis patients....
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