How Do Surface Properties of Nanoparticles Influence Their Diffusion in the Extracellular Matrix? A Model Study in Matrigel Using Polymer-Grafted Nanoparticles [0.03%]
纳米粒子的表面特性如何影响其在细胞外基质中的扩散?一项使用接枝聚合物的纳米颗粒在Matrigel中进行的模型研究
Marine Le Goas,Fabienne Testard,Olivier Taché et al.
Marine Le Goas et al.
Diffusion of nanomedicines inside the extracellular matrix (ECM) has been identified as a key factor to achieve homogeneous distribution and therefore therapeutic efficacy. Here, we sought to determine the impact of nanoparticles' (NPs) sur...
Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro [0.03%]
纳米颗粒的表面特性决定了其在体外人血脑屏障内皮细胞中的亚细胞定位及处理方式
Julia V Georgieva,Dharamdajal Kalicharan,Pierre-Olivier Couraud et al.
Julia V Georgieva et al.
A polarized layer of endothelial cells that comprises the blood-brain barrier (BBB) precludes access of systemically administered medicines to brain tissue. Consequently, there is a need for drug delivery vehicles that mediate transendothel...
Organic-inorganic hybrid nanoparticles: surface characteristics and interactions with a polyester resin [0.03%]
有机-无机杂化纳米颗粒的表面特性及与聚酯树脂的相互作用
David A Jesson,Marie-Laure Abel,John N Hay et al.
David A Jesson et al.
Organic-inorganic hybrid nanoparticles, derived from silica precursors with different organic functionalities (methyl, ethyl, vinyl, and phenyl) synthesized via a modified Stöber method have been investigated. These particles are intended ...
Surface characterization and properties of ordered arrays of CeO2 nanoparticles embedded in thin layers of SiO2 [0.03%]
嵌入超薄硅 dioxide层的有序排列的二氧化铈纳米颗粒的表面特性及性能研究
J Y Chane-Ching,M Airiau,A Sahibed-dine et al.
J Y Chane-Ching et al.
We demonstrated the surface composite character down to the nanometer scale of SiO(2)-CeO(2) composite high surface area materials, prepared using 5 nm colloidal CeO(2) nanoparticle building blocks. These materials are made of a homogeneous...